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63 papers found.
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A feed-forward regulation of endothelin receptors by c-Jun in human non-pigmented ciliary epithelial cells and retinal ganglion cells

: Shaoqing He. Data curation: Junming Wang, Hai-Ying Ma, Shaoqing He. Formal analysis: Junming Wang, Shaoqing He. Funding acquisition: Raghu R. Krishnamoorthy. Investigation: Junming Wang. Methodology ... : Junming Wang. Project administration: Hai-Ying Ma. Resources: Hai-Ying Ma, Thomas Yorio. Software: Shaoqing He. Supervision: Raghu R. Krishnamoorthy, Thomas Yorio. Validation: Junming Wang

Effects of Cu addition on microstructure and mechanical properties of as-cast Mg-6Zn magnesium alloy

The application of Mg-Zn binary alloys is restricted due to their developed dendritic microstructure and poor mechanical properties. In this study, an alloying method was used to improve the mechanical properties of Mg-Zn alloy. The Mg-6Zn magnesium alloys microalloyed with varying Cu content (0, 0.8, 1.5, 2.0 and 2.5wt.%) were fabricated by permanent mould casting, and the...

Laser-Assisted Reduction of Highly Conductive Circuits Based on Copper Nitrate for Flexible Printed Sensors

Stretchable electronic sensing devices are defining the path toward wearable electronics. High-performance flexible strain sensors attached on clothing or human skin are required for potential applications in the entertainment, health monitoring, and medical care sectors. In this work, conducting copper electrodes were fabricated on polydimethylsiloxane as sensitive stretchable...

Solidification behavior and rheo-diecasting microstructure of A356 aluminum alloy prepared by self-inoculation method

Semisolid slurry of A356 aluminum alloy was prepared by self-inoculation method, and the microstructure and solidification behavior during rheo-diecasting process were investigated. The results indicate that the semisolid slurry of A356 aluminum alloy can be prepared by self-inoculation method at 600 °C. Primary α-Al particles with fine and spherical morphologies are uniformly...

Clinical and survival analysis of 36 cases of primary fallopian tube carcinoma

Ying Ma 1 Wei Duan 0 0 Oncology Department, Beijing Obstetrics and Gynecology Hospital, Capital Medical University , 251, Yaojiayuan Street, Chaoyang District, Beijing 100026 , China 1 Obstetrical

Human papillomavirus genotypes associated with cervical precancerous lesions and cancer in the highest area of cervical cancer mortality, Longnan, China

Background The mortality of cervical cancer in Longnan is as high as 39/10 million, ranking first in China. Methods Between 2012 to 2016, 329 samples with cervicitis, cervical intraepithelial neoplasia grade 1 to 3 (CINI to III), and invasive squamous cell carcinoma (SCC) were collected. HPV genotypes were examined with a validated kit for 23 different HPV subtypes. Results...

Characterization of Fosfomycin Resistance Gene, fosB, in Methicillin-Resistant Staphylococcus aureus Isolates

To investigate the prevalence, location and genetic environments of fosfomycin-resistance (fos) genes in methicillin-resistant Staphylococcus aureus (MRSA) clinical strains, 67 fosfomycin-resistant MRSA strains were isolated from the blood and cerebrospinal fluid samples at a teaching hospital in Shanghai. The presence of fos genes in these clinical strains was detected by PCR...

Balancing selection and recombination as evolutionary forces caused population genetic variations in golden pheasant MHC class I genes

Background The major histocompatibility complex (MHC) genes are vital partners in the acquired immune processes of vertebrates. MHC diversity may be directly associated with population resistance to infectious pathogens. Here, we screened for polymorphisms in exons 2 and 3 of the IA1 and IA2 genes in 12 golden pheasant populations across the Chinese mainland to characterize their...

Carbon Isotope Composition of Nighttime Leaf-Respired CO2 in the Agricultural-Pastoral Zone of the Songnen Plain, Northeast China

Variations in the carbon isotope signature of leaf dark-respired CO2 (δ13CR) within a single night is a widely observed phenomenon. However, it is unclear whether there are plant functional type differences with regard to the amplitude of the nighttime variation in δ13CR. These differences, if present, would be important for interpreting the short-term variations in the stable...

The association between social capital and quality of life among type 2 diabetes patients in Anhui province, China: a cross-sectional study

Fuyong Hu and Li Niu carried out the study, participated in the survey and drafted the manuscript. Ren Chen and Ying Ma participated in the design of the study and performed the statistical analysis. Zhi

Antagonistic Interplay between MicroRNA-155 and IL-10 during Lyme Carditis and Arthritis

MicroRNA-155 has been shown to play a role in immune activation and inflammation, and is suppressed by IL-10, an important anti-inflammatory cytokine. The established involvement of IL-10 in the murine model of Borrelia burgdorferi-induced Lyme arthritis and carditis allowed us to assess the interplay between IL-10 and miR-155 in vivo. As reported previously, Mir155 was highly...

IL-33/ST2 Correlates with Severity of Haemorrhagic Fever with Renal Syndrome and Regulates the Inflammatory Response in Hantaan Virus-Infected Endothelial Cells

Background Hantaan virus (HTNV) causes a severe lethal haemorrhagic fever with renal syndrome (HFRS) in humans. Despite a limited understanding of the pathogenesis of HFRS, the importance of the abundant production of pro-inflammatory cytokines has been widely recognized. Interleukin 33 (IL-33) has been demonstrated to play an important role in physiological and pathological...

Surface-enhanced Raman spectra of medicines with large-scale self-assembled silver nanoparticle films based on the modified coffee ring effect

We report here a simple and innovative method to prepare large-scale silver nanoparticle films based on the controlled coffee ring effect. It is demonstrated that the films can be used as surface-enhanced Raman scattering probes to detect low-concentration medicines. Silver nanoparticles with the average size about 70 nm were prepared by reduction of silver nitride. In our...

Effect of Zn, Cu and Ni addition on microstructure and mechanical properties of as-cast Mg-Dy alloys

This paper presents some research information on the effects of Zn, Cu and Ni on the microstructure and mechanical properties of as-cast Mg-2Dy (at.%) alloys. The Mg-2Dy alloy is composed of α-Mg and Mg24Dy5 phases. With the addition of 0.5at.%Zn, 0.5at.%Cu and 0.5at.%Ni, respectively, besides α-Mg, the long period stacking order (LPSO) phases containing Zn, Cu, and Ni...

Associations between Social Support and Condom Use among Commercial Sex Workers in China: A Cross-Sectional Study

Objective The aim of this study was to investigate the association between social support and AIDS high-risk behaviors in commercial sex workers (CSWs) in China. Methods A cross-sectional study was performed based on a convenience sample. Data were collected through questionnaire interviews including information about social demographic characteristics, the Social Support Rating...

Electronic medical record-based multicondition models to predict the risk of 30 day readmission or death among adult medicine patients: validation and comparison to existing models

Background There is increasing interest in using prediction models to identify patients at risk of readmission or death after hospital discharge, but existing models have significant limitations. Electronic medical record (EMR) based models that can be used to predict risk on multiple disease conditions among a wide range of patient demographics early in the hospitalization are...

Investigation of possible molecular mechanisms underlying the regulation of adhesion in Vibrio alginolyticus with comparative transcriptome analysis

Adhesion capability to fish mucus, which can be affected by environmental conditions, is considered to be a key virulence factor of Vibrio alginolyticus although the molecular mechanism is still unclear. In the present study, V. alginolyticus was treated with stress conditions including Cu2+ (50 mg/L), Pb2+ (100 mg/L), Hg2+ (50 mg/L) and low pH (pH 5). We found these stress...

Albendazole and Corticosteroids for the Treatment of Solitary Cysticercus Granuloma: A Network Meta-analysis

Background Solitary cysticercus granuloma (SCG) is the commonest form of neurocysticercosis in the Indian subcontinent and in travelers. Several different treatment options exist for SCG. We conducted a Bayesian network meta-analysis of randomized clinical trials (RCTs) to identify the best treatment option to prevent seizure recurrence and promote lesion resolution for patients...

Validation of a Novel Clinical Prediction Score for Severe Coronary Artery Diseases before Elective Coronary Angiography

Objectives Coronary artery disease (CAD) severity is associated with patient prognosis. However, few efficient scoring systems have been developed to screen severe CAD in patients with stable angina and suspected CAD before coronary angiography. Here, we present a novel scoring system for CAD severity before elective coronary angiography. Methods Five hundred fifty-one patients...