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Different Antibody Response against the Coxsackievirus A16 VP1 Capsid Protein: Specific or Non-Specific

Coxsackievirus A16 (CA16) is one of the major causative agents of hand, foot, and mouth disease worldwide. The non-neutralizing antibody response that targets CA16 VP1 remains poorly elucidated. In the present study, antibody responses against CA16 VP1 in Shanghai blood donors and Shanxi individuals were analyzed by ELISA and inhibitory ELISA using five CA16 VP1 antigens: VP11...

High Prevalence of HIV Infection and Bisexual Networks among a Sample of Men Who Have Sex with Men in Eastern China

Objective To examine homosexual and heterosexual behaviors, behavioral networks and HIV infection among men who have sex with men (MSM) in Eastern China. Methods A cross-sectional survey was conducted among MSM in 2013 in a rural prefecture of Zhejiang province. Participants were interviewed for their sexual behaviors and sexual networks and were tested for HIV infection. Results...

Illicit Heroin and Methamphetamine Use among Methadone Maintenance Treatment Patients in Dehong Prefecture of Yunnan Province, China

(grant no. 2012ZX10001001-004 to Na He) and Shanghai Municipal Health Bureau (grant no. XBR2011043 to Na He; KBF201232 to Yingying Ding) and the Junior Faculty Award of Fudan University , grant no ... . JJF201016 to Yingying Ding 1 Editor: Wenzhe Ho, Temple University School of Medicine, UNITED STATES 2 1 Department of Epidemiology, School of Public Health, Fudan University , Shanghai , China , 2 The Key

Expression of ezrin, CD44, and VEGF in giant cell tumor of bone and its significance

Background This research aimed to study the role of ezrin, CD44, and VEGF in invasion, metastasis, recurrence, and prognosis of giant cell tumor of bone (GCTB) and its association with the clinical and pathological features of GCTB. Methods Expression status of ezrin, CD44, and VEGF in 80 GCTB tissues and its adjacent noncancerous tissue samples were measured with...

Motivations for sexual risk behaviors among older men in Shanghai, China: a qualitative study

. JJF201016 to Yingying Ding). 1. Goodroad BK : HIV and AIDS in people older than 50: a continuing concern . J Gerontol Nurs 2003 , 29 : 18 - 24 . 2. China Ministry of Health: 2012 China AIDS Response Progress

Abdominal obesity and its association with health-related quality of life in adults: a population-based study in five Chinese cities

Background This study aimed to investigate the prevalence of abdominal obesity and its association with the health-related quality of life (HRQOL) in a randomly selected Chinese sample. Methods A population-based sample of 3,600 residents aged 18–80 years was selected randomly from 5 Chinese cities. Demographic information, and waist and hip circumference measurements were...

Alcohol Use and Subsequent Sex among HIV-Infected Patients in an Ethnic Minority Area of Yunnan Province, China

Objective To examine alcohol use and subsequent HIV risky behaviors among a sample of predominately ethnic minority people living with HIV/AIDS (PLWHA) in a rural community in Yunnan Province, China. Method A cross-sectional study with a face-to-face questionnaire interview was conducted among eligible participants. Results In total, 455 (94.4%) out of 482 eligible HIV patients...

Changes in Sexual Behaviors among HIV-Infected Individuals after Their HIV Diagnosis in a Rural Prefecture of Eastern China

Objective To describe changes in sexual behaviors among HIV-infected individuals after their HIV diagnosis. Methods All HIV-infected individuals diagnosed by the end of 2009 in Taizhou Prefecture were invited to participate in this 12-month prospective study. Assessments including the total number and types of sexual contacts, and condom use details for up to their most familiar...

Behavioral and Molecular Tracing of Risky Sexual Contacts in a Sample of Chinese HIV-infected Men Who Have Sex With Men

Haijiang Lin Na He Sujuan Zhou Yingying Ding Danhong Qiu Tiejun Zhang Frank Y. Wong Contact tracing, coupled with molecular epidemiologic investigation, is especially useful for identifying an ... China. ACKNOWLEDGMENTS Author affiliations: Department of Epidemiology, School of Public Health, Fudan University, Shanghai, China (Haijiang Lin, Na He, Sujuan Zhou, Yingying Ding, Tiejun Zhang); Key

Tracing sexual contacts of HIV-infected individuals in a rural prefecture, Eastern China

BackgroundContact tracing is especially useful for identifying an infection with few cases in the population, such as HIV in China. Little such research is available in China.MethodsEvery newly diagnosed HIV case from 2008–2010 in Taizhou Prefecture, Zhejiang Province in China, was invited to participate as an “index case” in a contact tracing survey by providing contact...

Community Based Promotion on VCT Acceptance among Rural Migrants in Shanghai, China

Objective Voluntary counseling and testing (VCT) plays an important integral role in response to the HIV/AIDS epidemic. However, VCT service has not been effectively utilized among rural migrants, a high risk group in China. In this study, we developed a community based intervention to examine if community mobilization with comprehensive VCT is more effective than current HIV...

Characterization of Tat Antibody Responses in Chinese Individuals Infected with HIV-1

HIV-1 Tat is an important regulatory protein involved in AIDS pathogenesis. However, the immunoprofiles of anti-Tat responses remain unclear. We analysed the immunoprofiles of the anti-Tat antibody responses and the neutralizing activities. Out of 326 HIV-1-seropositive individuals, 12.9% were positive for anti-Tat antibodies. We found six different immunological profiles of anti...

Antiretroviral Therapy Reduces HIV Transmission in Discordant Couples in Rural Yunnan, China

), Keming Rou (NCAIDS, China CDC), Na He (Fudan University), and Haiying Fan (NCAIDS, China CDC) served as the Coordination Team. Na He (Fudan University), Zhuohua Fu (Fudan University), Yingying Ding (Fudan