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256 papers found.
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A survey of deep learning-based 3D shape generation

media learning, 3D reconstruction, and 3D understanding. Yong-Liang Yang is a senior lecturer in the Department of Computer Science at the University of Bath, UK. He received his B.S. and Ph.D. degrees

Spatiotemporal transcriptomic atlas reveals the dynamic characteristics and key regulators of planarian regeneration

Province, School of Life Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences , Hangzhou 310024, Zhou, Jun Cai, Shihua Zhang, Yun-Gui Yang 10 Yong-Liang Zhao Whole-body

Structural insights into cyanobacterial RuBisCO assembly coordinated by two chaperones Raf1 and RbcX

RuBisCO is the most abundant enzyme in nature, catalyzing the fixation of CO2 in photosynthesis. Its common form consists of eight RbcL and eight RbcS subunits, the assembly of which requires a series of chaperones that include RbcX and RuBisCO accumulation factor 1 (Raf1). To understand how these RuBisCO-specific chaperones function during cyanobacterial RbcL8RbcS8 (L8S8...

MEX3A promotes nasopharyngeal carcinoma progression via the miR-3163/SCIN axis by regulating NF-κB signaling pathway

Mex-3 RNA Binding Family Member A (MEX3A) is an RNA-binding protein that plays complex and diverse roles in the development of various malignancies. However, its role and mechanism in nasopharyngeal carcinoma (NPC) remain undefined and were therefore evaluated in this study. By analyzing Gene Expression Omnibus data and using tissue microarrays, we found that MEX3A is...

Multichannel adaptive signal detection: basic theory and literature review

Multichannel adaptive signal detection uses test and training data jointly to form an adaptive detector to determine whether a target exists. The resulting adaptive detectors typically possess constant false alarm rate (CFAR) properties; thus, no additional CFAR processing is required. In addition, a filtering process is also not required because the filtering function is...

B3GALT4 remodels the tumor microenvironment through GD2-mediated lipid raft formation and the c-met/AKT/mTOR/IRF-1 axis in neuroblastoma

Beta-1,3-galactosyltransferase-4 (B3GALT4) plays a critical regulatory role in tumor biology. However, the role of B3GALT4 in modulating the tumor microenvironment (TME) of neuroblastoma (NB) remains unknown. Public datasets and clinical NB samples were collected to evaluate the expression and clinical significance of GD2 and B3GALT4 in NB patients. CCK-8, colony formation, and...

Unusual shrinkage and reshaping of Earth’s magnetosphere under a strong northward interplanetary magnetic field

The Earth’s magnetosphere is the region of space where plasma behavior is dominated by the geomagnetic field. It has a long tail typically extending hundreds of Earth radii (RE) with plentiful open magnetic fluxes threading the magnetopause associated with magnetic reconnection and momentum transfer from the solar wind. The open-flux is greatly reduced when the interplanetary...

Nsun2 coupling with RoRγt shapes the fate of Th17 cells and promotes colitis

T helper 17 (Th17) cells are a subset of CD4+ T helper cells involved in the inflammatory response in autoimmunity. Th17 cells secrete Th17 specific cytokines, such as IL-17A and IL17-F, which are governed by the master transcription factor RoRγt. However, the epigenetic mechanism regulating Th17 cell function is still not fully understood. Here, we reveal that deletion of RNA 5...

Association of genetic polymorphisms of PCSK9 with type 2 diabetes in Uygur Chinese population

PCSK9 gene expression is associated with biological processes such as lipid metabolism, glucose metabolism, and inflammation. In the present study, our primary objective was to assess the association between the single-nucleotide polymorphisms in the PCSK9 gene and type 2 diabetes in Uygur subjects, in Xinjiang, China. We designed a case–control study including 662 patients...

Mesencephalic astrocyte-derived neurotrophic factor reprograms macrophages to ameliorate acetaminophen-induced acute liver injury via p38 MAPK pathway

Acetaminophen (APAP)-induced liver injury (AILI) is the most frequent cause of acute liver failure; but the underlying mechanisms still remain obscure. Macrophages and endoplasmic reticulum (ER) stress play an important role in the pathogenesis of AILI. Mesencephalic astrocyte-derived neurotrophic factor (MANF) is a newly identified 18-kDa soluble protein, whose expression and...

Deep learning based solder joint defect detection on industrial printed circuit board X-ray images

With the improvement of electronic circuit production methods, such as reduction of component size and the increase of component density, the risk of defects is increasing in the production line. Many techniques have been incorporated to check for failed solder joints, such as X-ray imaging, optical imaging and thermal imaging, among which X-ray imaging can inspect external and...

Structures of cyanobacterial bicarbonate transporter SbtA and its complex with PII-like SbtB

-Liang Jiang 0 Cong-Zhao Zhou 0 0 Hefei National Laboratory for Physical Sciences at the Microscale and School of Life Sciences, University of Science and Technology of China , Hefei, Anhui , China Dear

Study on the Antibody Level Differences of PED IgG and IgA, TGE IgG and PoR IgG After Immunization with Different Porcine Viral Diarrhea Vaccine Combinations

To prevent porcine viral diarrhea, a vaccine combination that can provide good antibody levels needs to be determined. In this study, we screened 30 pregnant sows divided into six experimental groups, namely, five immunized groups and one control group, to investigate the antibody level differences of different vaccine combinations on porcine epidemic diarrhea (PED), porcine...

Interactive modeling of lofted shapes from a single image

Tsinghua University in 2018. He is currently a Ph.D. candidate in computer science in Tsinghua University. His research interests include computer vision and computer graphics. Yong-Liang Yang received his

Genetic Characterization of Porcine Parvovirus 7 (PPV7) Isolates in Fujian, China

In this study, we sequenced and analyzed the complete genomes of the porcine parvovirus 7 (PPV7) isolated in Fujian, Southeast China. Genomic comparison revealed that PPV7 isolates in Fujian shared higher (more than 98.5%) nucleotide homology and closer relationship with other PPV7 strains. Phylogenetic analysis based on NS indicated that PPV7 formed a distinct cluster (proposed...

Calcium/calmodulin-dependent protein kinase IV promotes imiquimod-induced psoriatic inflammation via macrophages and keratinocytes in mice

CaMK4 has an important function in autoimmune diseases, and the contribution of CaMK4 in psoriasis remains obscure. Here, we show that CaMK4 expression is significantly increased in psoriatic lesional skin from psoriasis patients compared to healthy human skin as well as inflamed skin from an imiquimod (IMQ)-induced mouse model of psoriasis compared to healthy mouse skin. Camk4...

Mild Traumatic Brain Injury Causes Nociceptive Sensitization through Spinal Chemokine Upregulation

High rates of acute and chronic pain are associated with traumatic brain injury (TBI), but mechanisms responsible for the association remain elusive. Recent data suggest dysregulated descending pain modulation circuitry could be involved. Based on these and other observations, we hypothesized that serotonin (5-HT)-dependent activation of spinal CXC Motif Chemokine Receptor 2...

MiR-125b-2 knockout increases high-fat diet-induced fat accumulation and insulin resistance

‑Jie Sun 0 Qian‑Yun Xi 0 YongLiang Zhang 0 0 Guangdong Provincial Key Laboratory of Agro-Animal Genomics and Molecular Breeding, Guangdong Provincial Key Laboratory of Animal Nutrition Control, South

3D computational modeling and perceptual analysis of kinetic depth effects

( ), Miao Wang2 , Yong-Liang Yang3 , Yu-Kun Lai4 , and Paul L. Rosin4 c The Author(s) 2020. Abstract Humans have the ability to perceive kinetic depth effects, i.e., to perceived 3D shapes from 2D ... University. His research interests lie in virtual reality and computer graphics, with a particular focus on content creation for virtual reality. Yong-Liang Yang received his Ph.D. degree in computer science