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31 papers found.
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Identification and cytochemical immunolocalization of acetyl-CoA acetyltransferase involved in the terpenoid mevalonate pathway in Euphorbia helioscopia laticifers

Background Terpenoids, the largest class of natural products in the plant kingdom, have been widely used in medicine. The precursors of terpenoids, isoprene phosphate (IPP) and dimethylallyl pyrophosphate (DMAPP), were synthesized from a mevalonate (MVA) pathway and a 2-C-methyl-d-erythritol-4-phosphate (MEP) pathway respectively. The acetyl-CoA acetyltransferase (AACT) is the...

Green material selection for sustainability: A hybrid MCDM approach

Green material selection is a crucial step for the material industry to comprehensively improve material properties and promote sustainable development. However, because of the subjectivity and conflicting evaluation criteria in its process, green material selection, as a multi-criteria decision making (MCDM) problem, has been a widespread concern to the relevant experts. Thus...

Flow and fracture behavior of aluminum alloy 6082-T6 at different tensile strain rates and triaxialities

triaxiality. Data curation: Xuanzhen Chen, Shan Peng, Ping Xu. Formal analysis: Xuanzhen Chen, Song Yao, Chao Chen. Funding acquisition: Yong Peng. Investigation: Xuanzhen Chen, Yong Peng, Shan Peng, Song ... Yao, Chao Chen, Ping Xu. Methodology: Yong Peng. Project administration: Yong Peng. Resources: Shan Peng, Chao Chen. Software: Xuanzhen Chen, Shan Peng, Song Yao, Chao Chen. Supervision: Yong Peng

Identification of odorant binding proteins and chemosensory proteins in Microplitis mediator as well as functional characterization of chemosensory protein 3

Editing Services. Author Contributions Conceptualization: Rui-Jun Li, Yong-Jun Zhang, Yu-Yuan Guo. Data curation: Yong Peng, Shan-Ning Wang, Ke-Ming Li, Jing-Tao Liu, Yao Zheng, Shuang Shan, Ye-Qing ... Yang, Rui-Jun Li, Yong-Jun Zhang. Formal analysis: Yong Peng, Shan-Ning Wang, Yong-Jun Zhang. Funding acquisition: Yong-Jun Zhang, Yu-Yuan Guo. Investigation: Yong Peng, Shan-Ning Wang, Ke-Ming Li

Supplement of levosimendan to epinephrine improves initial resuscitation outcomes from asphyxial cardiac arrest

Background Levosimendan exerted favorable effects on the initial outcome in the treatment of ventricular fibrillation cardiac arrest. This study investigated the efficacy of levosimendan in the treatment of asphyxia-induced cardiac arrest in rats. Methods Animals underwent asphyxial cardiac arrest/cardiopulmonary resuscitation, randomized to three treatment groups: epinephrine...

Clinicopathological and prognostic significance of mTOR and phosphorylated mTOR expression in patients with esophageal squamous cell carcinoma: a systematic review and meta-analysis

Background Mammalian target of rapamycin (mTOR) is a serine/threonine protein kinase responsible for regulating ribosomal biogenesis and protein synthesis. Dysregulation of mTOR contributes to tumorigenesis, angiogenesis, cellular growth and metastasis but its roles in esophageal squamous cell carcinoma (ESCC) are controversial. Therefore, the objective of this study is to...

Realization of III–V Semiconductor Periodic Nanostructures by Laser Direct Writing Technique

-qiang Ning Yong Peng Zi-yang Zhang 0 0 Key Laboratory of Nanodevices and Applications, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences , 215123 Suzhou , People's Republic of

Elevated Cellular PD1/PD-L1 Expression Confers Acquired Resistance to Cisplatin in Small Cell Lung Cancer Cells

Although small cell lung cancer (SCLC) is highly responsive to chemotherapies (e.g., cisplatin-etoposide doublet), virtually almost all responsive SCLC patients experience disease recurrence characterized by drug resistance. The mechanisms underlying cisplatin resistance remain elusive. Here we report that cell-intrinsic expression of PD1 and PD-L1, two immune checkpoints, is...

Why is population information crucial for taxonomy? A case study involving a hybrid swarm and related varieties

Hybridization has become a focal topic in evolutionary biology, and many taxonomists are aware that the process occurs more frequently than previously assumed. Nonetheless many species and varieties are still described without explicitly considering the possibility of hybridization, especially in countries that have relatively short scientific histories, but which often possess...

Why is population information crucial for taxonomy? A case study involving a hybrid swarm and related varieties

Hybridization has become a focal topic in evolutionary biology, and many taxonomists are aware that the process occurs more frequently than previously assumed. Nonetheless many species and varieties are still described without explicitly considering the possibility of hybridization, especially in countries that have relatively short scientific histories, but which often possess...

Identification, characterization, and utilization of single copy genes in 29 angiosperm genomes

Background Single copy genes are common across angiosperm genomes. With the sufficiently high quality sequenced genomes, the identification of large-scale single copy genes among multiple species is possible. Although some characteristics have been reported, our study provides novel insights into single copy genes. Results We identified single copy genes across 29 angiosperm...

The influence of body composition on renal function in patients with coronary artery disease and its prognostic significance: a retrospective cohort study

Objective We try to analyse the effect of renal functions on death in CAD patients with different body compositions. Methods A retrospective analysis was conducted in 2989 consecutive patients with CAD confirmed by coronary angiography were enrolled and were grouped into two categories: basically preserved renal function (PRF) (eGFR ≥60 ml/min) and obviously reduced renal...

Natural hybridization and asymmetric introgression at the distribution margin of two Buddleja species with a large overlap

Background Natural hybridization in plants is universal and plays an important role in evolution. Based on morphology it has been presumed that hybridization occurred in the genus Buddleja, though genetic studies confirming this assumption have not been conducted to date. The two species B. crispa and B. officinalis overlap in their distributions over a wide range in South-West...

Chemical and biological research of Clematis medicinal resources

Clematis is a botanical source for various pharmaceutically active components, which has long been used in conventional medicine since the beginning of Chinese civilization. Increasing interest in Clematis medicinal resources has led to additional discoveries of triterpenoid saponins, flavonoids, coumarins, alkaloids and many other compounds in various Clematis species, and to...

Immunocytochemical localization of saikosaponin-d in vegetative organs of Bupleurum scorzonerifolium Willd

Xueyan Zhao 0 Li Zheng 0 Jingjing Si Yan Miao Yong Peng Xia Cai 0 Equal contributors Key Laboratory of Resource Biology and Biotechnology in western China, (Northwest University) , Ministry of

Evaluation of the content variation of anthraquinone glycosides in rhubarb by UPLC-PDA

Background Rhubarb is an important Chinese medicinal herb with a long history of over 2000 years and has been commonly used as a laxative. It is the radix and rhizome of Rheum officinale Baill., R. palmatum L. and R. tanguticum Maxim, all of which are mainly distributed in a broad region in the Tibetan plateau. Anthraquinone glycosides are a series of major active ingredients...

CT Image Sequence Restoration Based on Sparse and Low-Rank Decomposition

Blurry organ boundaries and soft tissue structures present a major challenge in biomedical image restoration. In this paper, we propose a low-rank decomposition-based method for computed tomography (CT) image sequence restoration, where the CT image sequence is decomposed into a sparse component and a low-rank component. A new point spread function of Weiner filter is employed to...

The influence of body composition on the N-terminal pro-B-type natriuretic peptide level and its prognostic performance in patients with acute coronary syndrome: a cohort study

Background Whether body composition is associated with the N-terminal pro-B-type natriuretic peptide (NT-proBNP) level and its prognostic performance in acute coronary syndrome (ACS) remains unknown. We aimed to investigate the influence of body composition on the NT-proBNP level and its prognostic performance among ACS patients. Methods In total, 1623 ACS patients with NT-proBNP...

The large-leaved Kudingcha (Ilex latifolia Thunb and Ilex kudingcha C.J. Tseng): a traditional Chinese tea with plentiful secondary metabolites and potential biological activities

In China, Kudingcha has been used for almost 2,000 years as a tea to quench thirst, remove phlegm, refresh the mind, and improve eyesight. The group of large-leaved Kudingcha is coveted for its potential effects on lipid metabolism, which are attributed to the presence of characteristic ingredients. This contribution reviews studies from the past few decades regarding the plant...

PreDNA: accurate prediction of DNA-binding sites in proteins by integrating sequence and geometric structure information

Motivation: Protein–DNA interactions often take part in various crucial processes, which are essential for cellular function. The identification of DNA-binding sites in proteins is important for understanding the molecular mechanisms of protein–DNA interaction. Thus, we have developed an improved method to predict DNA-binding sites by integrating structural alignment algorithm...