Conceptualization: Linghang Wang, Yonghong Zhang, Keyi Xu, Tao Dong, Sarah Rowland Jones, Louis-Marie Yindom. Data curation: Linghang Wang, Louis-Marie Yindom. Formal analysis: Linghang Wang, Yonghong Zhang, Tao ... Dong, Louis-Marie Yindom. Funding acquisition: Keyi Xu, Tao Dong, Sarah Rowland-Jones. Investigation: Linghang Wang, Yonghong Zhang, Louis-Marie Yindom. Methodology: Linghang Wang, Yonghong Zhang
Morales. Methodology: Benxu Cheng. Project administration: Benxu Cheng. Resources: Benxu Cheng, Yonghong Zhang, Shizue Mito. Supervision: Benxu Cheng. Validation: Benxu Cheng. Visualization: Benxu ... Cheng, Liza Doreen Morales. Writing ± original draft: Benxu Cheng. Writing ± review & editing: Benxu Cheng, Liza Doreen Morales, Yonghong Zhang, Shizue Mito, Andrew Tsin. 15 / 18 States. Clin Cancer
sequence of the EU_6_A1 isolate for assembly of its mitochondrial genome. Conceptualization: Frank N. Martin, David E. L. Cooke, Mike D. Coffey. Data curation: Frank N. Martin, Yonghong Zhang, David E. L ... . Cooke. Formal analysis: Frank N. Martin, David E. L. Cooke, Niklaus J. Gru?nwald. Investigation: Frank N. Martin, Yonghong Zhang, David E. L. Cooke, William E. Fry. Methodology: Frank N. Martin, David E
Natural Science Foundation of China (31590823 to HS), National Natural Science Foundation of China (31260198 to HYJ), National Natural Science Foundation of China (31460050 Dr. Yonghong Zhang), Academic and
Glycerol metabolism has been well studied biochemically. However, the means by which glycerol functions in plant development is not well understood. This study aimed to investigate the mechanism underlying the effects of glycerol on root development in Arabidopsis thaliana. Exogenous glycerol inhibited primary root growth and altered lateral root development in wild-type plants...
Over 95% of CD4 cell death occurs by Caspase-1-mediated pyroptosis during HIV infection. Caspase-3-mediated apoptosis accounts for the death in a small proportion of infected CD4 cells. To date, there have been no reports on the dynamics of Caspase-1 and Caspase-3 and their relationship with disease progression in acute HIV-1 infection. In this study, two distinct HIV-1 patient...
roots of WT and hy5 mutants, related to S6D and S6E Fig. (XLSX) 12 / 15 Author Contributions Conceptualization: Chen Li, Guodong Wang, Lanlan Zheng. Data curation: Yonghong Zhang, Jiajing Wang ... , Jingwei Yang, Guodong Wang. Funding acquisition: Yonghong Zhang, Chen Li, Guodong Wang, Lanlan Zheng. Investigation: Yonghong Zhang, Guodong Wang, Lanlan Zheng. Methodology: Chen Li, Jiajing Wang, Guodong
Hongmei Li 0 Mingzhi Zhang 0 Yonghong Zhang 0 Masaru Katoh, National Cancer Center, Japan 0 Department of Epidemiology, School of Public Health, Medical College of Soochow University , Suzhou , China
Objective We aimed to evaluate the controversial association between human urotensin II and essential hypertension in untreated hypertensive cases and normotensive controls. Methods 197 newly diagnosed hypertensive patients and 197 age- and sex-matched normotensive controls were studied. Plasma urotensin II, nitric oxide metabolites, and other traditional biomarkers were examined...
Objective This study aims to examine the association between inflammatory biomarkers and dyslipidemia and its components among Mongolians in China. Methods Data were obtained from 2544 Mongolians via standard questionnaires and blood samples in Inner Mongolia, China. High sensitivity C-reactive protein (hsCRP), soluble intercellular adhesion molecule-1 (sICAM-1) and soluble E...
Background Association between vitamin D insufficiency and hyperuricemia has not been reported so far. We aimed to study the association of vitamin D insufficiency with elevated serum uric acid among middle-aged and elderly Chinese Han women. Methods We collected data from participants residing in Jinchang district of Suzhou from January to May, 2010. Serum uric acid, 25-hydroxy...
Elucidating protective immunity against HCV is important for the development of a preventative vaccine. We hypothesize that spontaneous resolution of acute HCV infection offers clue to protective immune responses, and that DAA therapy affects the quality and quantity of HCV-specific T cell responses. To test these hypotheses, we performed T cell epitope mapping in 111 HCV...
The homeobox gene (HOXA13) codes for a transcription factor protein that binds to AT-rich DNA sequences and controls expression of genes during embryonic morphogenesis. Here we present the NMR structure of HOXA13 homeodomain (A13DBD) bound to an 11-mer DNA duplex. A13DBD forms a dimer that binds to DNA with a dissociation constant of 7.5 nM. The A13DBD/DNA complex has a molar...
Heading date and grain weight are two determining agronomic traits of crop yield. To date, molecular factors controlling both heading date and grain weight have not been identified. Here we report the isolation of a hemizygous mutation, heading and grain weight (hgw), which delays heading and reduces grain weight in rice. Analysis of hgw mutant phenotypes indicate that the...
DNA methylation is known to play an important role in regulating gene expression during biological development and tissue differentiation in eukaryotes. In this study, we used the fluorescence-labeled methylation-sensitive amplified polymorphism (F-MSAP) method to assess the extent and pattern of cytosine methylation in muscle, heart, liver, spleen, lung, kidney and stomach from...
A major challenge to developing a successful HIV vaccine is the vast diversity of viral sequences, yet it is generally assumed that an epitope conserved between different strains will be recognised by responding T-cells. We examined whether an invariant HLA-B8 restricted Nef90–97 epitope FL8 shared between five high titre viruses and eight recombinant vaccinia viruses expressing...
