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Molecular basis of binding between the global post-transcriptional regulator CsrA and the T3SS chaperone CesT

Collaborative Innovation Center of Biotherapy, Chengdu, Sichuan, 610041, ChinaFei Ye, Fanli Yang, Ruijie Yu, Xi Lin, Zhujun Chen, Yu Cao, Yuquan Wei & Guangwen LuCAS Key Laboratory of Pathogenic Microbiology and ... in:Nature Research journals • PubMed • Google Scholar Search for Yu Cao in:Nature Research journals • PubMed • Google Scholar Search for Yuquan Wei in:Nature Research journals • PubMed • Google Scholar

A mitochondria-targeting artemisinin derivative with sharply increased antitumor but depressed anti-yeast and anti-malaria activities

was supported by grants from the National Science Foundation of China (31123004) and the National Basic Research Program of China (2013CB910700). Author information Author notesChen Sun & Yu Cao ... These authors contributed equally to this work. AffiliationsState Key Laboratory of Membrane Biology, School of Life Sciences, Tsinghua University, Beijing 100084, ChinaChen Sun, Yu Cao, Pan Zhu & Bing

Minimising efficiency roll-off in high-brightness perovskite light-emitting diodes

, Nana Wang, Yu Cao, Yanfeng Miao, Mengmeng Xu, Qiang Guo, Li Zhang, Chang Yi, Jianpu Wang & Wei HuangSchool of Physical Science and Information Technology, Liaocheng University, Liaocheng, 252059 ... Research journals • PubMed • Google Scholar Search for Yu Cao in:Nature Research journals • PubMed • Google Scholar Search for Yanfeng Miao in:Nature Research journals • PubMed • Google Scholar Search for

Effect of adherence on daytime sleepiness, fatigue, depression and sleep quality in the obstructive sleep apnea/hypopnea syndrome patients undertaking nasal continuous positive airway pressure therapy

therapy Yeying Wang,1,2 Li Ai,1 Jiahong Luo,2 Ran Li,1 Yanlin Chai,1 Xiaojie He,1 Yu Cao,1 Yongxia Li1 1Department of Respiratory Medicine, The Second Affiliated Hospital of Kunming Medical University

SFRP2 enhances the osteogenic differentiation of apical papilla stem cells by antagonizing the canonical WNT pathway

Background Exploring the molecular mechanisms underlying directed differentiation is helpful in the development of clinical applications of mesenchymal stem cells (MSCs). Our previous study on dental tissue-derived MSCs demonstrated that secreted frizzled-related protein 2 (SFRP2), a Wnt inhibitor, could enhance osteogenic differentiation in stem cells from the apical papilla...

Fscn1 is required for the trafficking of TGF-β family type I receptors during endoderm formation

100101, ChinaZhaoting Liu, Guozhu Ning, Ranran Xu, Yu Cao & Qiang WangTsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, ChinaAnming MengSavaid Medical ... Research journals • PubMed • Google ScholarSearch for Ranran Xu in:Nature Research journals • PubMed • Google ScholarSearch for Yu Cao in:Nature Research journals • PubMed • Google ScholarSearch for Anming

L-Arginine supplementation inhibits the growth of breast cancer by enhancing innate and adaptive immune responses mediated by suppression of MDSCs in vivo

Background L-Arg is involved in many biological activities, including the activation of T cells. In breast cancer patients, L-Arg is depleted by nitric oxide synthase 2 (NOS2) and arginase 1 (ARG-1) produced by myeloid-derived suppressor cells (MDSCs). Our aim was to test whether L-Arg supplementation could enhance antitumor immune response and improve survivorship in a rodent...

Diagnostic accuracy of the postoperative ratio of C-reactive protein to albumin for complications after colorectal surgery

Background The ratio of C-reactive protein to albumin, as a novel inflammation-based prognostic score, is associated with outcomes in cancer and septic patients. The diagnostic accuracy of the CRP/albumin ratio has not been assessed in colorectal surgery for postoperative complications. Methods A total of 359 patients undergoing major colorectal surgery between 2012 and 2015 were...

Reproductive Allocation in Three Macrophyte Species from Different Lakes with Variable Eutrophic Conditions

Reproductive allocation is a key process in the plant life cycle and aquatic plants exhibit great diversity in their reproductive systems. In the present study, we conduct a field investigation of three aquatic macrophytes: Stuckenia pectinata, Myriophyllum spicatum, and Potamogeton perfoliatus. Our results showed that widespread species, including S. pectinata and M. spicatum...

Etoposide Induces Apoptosis in Activated Human Hepatic Stellate Cells via ER Stress

Hospital, Medical School of Nanjing University, Nanjing, ChinaChen Wang, Feng Zhang, Yu Cao, Mingming Zhang, Aixiu Wang, Min Su, Ming Zhang & Yuzheng ZhugeDepartment of Gastroenterology, Affiliated Drum ... Research journals • PubMed • Google ScholarSearch for Yu Cao in:Nature Research journals • PubMed • Google ScholarSearch for Mingming Zhang in:Nature Research journals • PubMed • Google ScholarSearch for

Tumor Necrosis Factor-Like Weak Inducer of Apoptosis Promotes Hepatic Stellate Cells Migration via Canonical NF-κB/MMP9 Pathway

In the liver, the signal and function of tumor necrosis factor-like weak inducer of apoptosis (TWEAK) have mainly been assessed in association with liver regeneration. However, the effects of TWEAK on liver fibrosis have not been fully elucidated. To investigate the effects of TWEAK on human hepatic stellate cells (HSCs) and to explore the relevant potential mechanisms, human...

The octanol/water distribution coefficients of ardipusilloside-I and its metabolites, and their permeation characteristics across Caco-2 cell monolayer

BackgroundArdipusilloside-I (ADS-I) is a triterpenoid saponin extracted from Chinese medicinal herb Ardisiapusill A. DC. Previous studies have demonstrated the potent anti-tumor activities of ADS-I both in vitro and in vivo, and its main metabolites (M1 and M2) from human intestinal bacteria. However, the physicochemical properties and intestinal permeation rate of ADS-I and its...

Horizontal Transfer of a Novel Soil Agarase Gene from Marine Bacteria to Soil Bacteria via Human Microbiota

Key Laboratory of Sichuan Province, College of Life Sciences, Sichuan University, Chengdu, 610065, P. R. ChinaTao Song, Hui Xu, Congchong Wei, Tengfei Jiang, Shishang Qin, Weijia Zhang, Yu Cao, Chao Hu ... ScholarSearch for Yu Cao in:Nature Research journals • PubMed • Google ScholarSearch for Chao Hu in:Nature Research journals • PubMed • Google ScholarSearch for Fan Zhang in:Nature Research journals • PubMed

Periodontal regeneration in swine after cell injection and cell sheet transplantation of human dental pulp stem cells following good manufacturing practice

Background Periodontitis, one of the most prevalent infectious diseases in humans, results in the destruction of tooth-supporting tissues. The purpose of the present study is to evaluate the effect of cell injection and cell sheet transplantation on periodontal regeneration in a swine model. Methods In the present study, human dental pulp stem cells (hDPSCs) were transplanted...

A Sustainable Financing Credit Rating Model for China’s Small- and Medium-Sized Enterprises

, Hunan 410004, China Received 26 December 2013; Revised 20 February 2014; Accepted 23 February 2014; Published 31 March 2014 Academic Editor: Fenghua Wen Copyright © 2014 Yu Cao and Shouyao Xiong

Aspirin promotes bone marrow mesenchymal stem cell-based calvarial bone regeneration in mini swine

Introduction Stem cells have great therapeutic potential due to their capacity for self-renewal and their potential for differentiating into multiple cell lineages. It has been recently shown that the host immune system has fundamental effects on the fate of transplanted mesenchymal stem cells during bone repair, where the topical administration of aspirin is capable of improving...

Oxidative Stress and Carbonyl Lesions in Ulcerative Colitis and Associated Colorectal Cancer

. Authors’ Contribution Zhiqi Wang wrote draft. Sai Li draw figures. Duan-Fang Liao, Yu Cao, Xuefei Tian, and Rong Zeng contributed to literature search and discussion. Deliang Cao revised the paper. All

Oxidative Stress and Carbonyl Lesions in Ulcerative Colitis and Associated Colorectal Cancer

. Authors’ Contribution Zhiqi Wang wrote draft. Sai Li draw figures. Duan-Fang Liao, Yu Cao, Xuefei Tian, and Rong Zeng contributed to literature search and discussion. Deliang Cao revised the paper. All

Effect of Urinary Protease Inhibitor (Ulinastatin) on Cardiopulmonary Bypass: A Meta-Analysis for China and Japan

Objectives A meta-analysis was conducted to investigate the effects of ulinastatin treatment on adult patients undergoing cardiac surgery under cardiopulmonary bypass (CPB). Methods Seven electronic databases were searched for reports of randomized, controlled trials conducted up to February 2014 in which patients undergoing cardiac surgery with CPB were administered ulinastatin...