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Increased Overall Survival and Decreased Cancer-Specific Mortality in Patients with Hepatocellular Carcinoma Treated by Transarterial Chemoembolization and Human Adenovirus Type-5 Combination Therapy: a Competing Risk Analysis

tumor, and HBsAg-positivity. Hepatocellular carcinoma; Transarterial chemoembolization; Human type-5 adenovirus; Competing risk analysis; Cancer-specific mortality - Chaobin He and Yu Zhang contributed ... . Xiangming Lao from the Department of Hepatopancreatobiliary Oncology in Sun Yat-sen University Cancer Center for reviewing the manuscript. Author’s Contributions Chaobin He, Yu Zhang, and Xiaojun Lin were

Effect of panel shape on hydrodynamic performances of vertical v-shaped double- slotted cambered otter-board

The effect of panel shape on hydrodynamic performances of a vertical v-shaped double-slotted cambered otter-board was investigated using engineering models in a wind tunnel. Three different shape panels (rhomboid, left trapezoid and isosceles trapezoid) were evaluated at a wind speed of 28 m/s. Parameters measured included: drag coefficient Cx, lift coefficient Cy, pitch moment...

Transmission completion time minimization in digital network coding assisted two-way relay OFDM networks

This paper investigates the two-way relay transmission over orthogonal frequency division multiplexing (OFDM) channels using digital network coding. For a given amount of data to be transmitted, we formulate an optimization problem to minimize the total transmission completion time by jointly allocating the power and assigning the subcarriers under individual power constraints...

Chlorophyll, carotenoid and vitamin C metabolism regulation in Actinidia chinensis 'Hongyang' outer pericarp during fruit development

China (NSFC) (31401854) and the Natural Science Foundation of Jiangsu Province (grant no. BK20140760). Author Contributions Data curation: Ji-Yu Zhang, De-Lin Pan, Zhan-Hui Jia. Funding acquisition: Ji ... -Yu Zhang, Zhong-Ren Guo. Investigation: Tao Wang. Methodology: De-Lin Pan, Zhan-Hui Jia, Tao Wang, Gang Wang. Project administration: Ji-Yu Zhang. Supervision: Ji-Yu Zhang, Zhong-Ren Guo

MRHCA: a nonparametric statistics based method for hub and co-expression module identification in large gene co-expression network

), which is supported by National Science Foundation grant ( No. ACI-1548562). COMPLIANCE WITH ETHICS GUIDELINES The authors Yu Zhang, Sha Cao, Jing Zhao, Burair Alsaihati, Qin Ma and Chi Zhang declare that

Culture-based study on the development of antibiotic resistance in a biological wastewater system treating stepwise increasing doses of streptomycin

The effects of streptomycin (STM) on the development of antibiotic resistance in an aerobic-biofilm reactor was explored by stepwise increases in STM doses (0–50 mg L−1), over a period of 618 days. Totally 191 bacterial isolates affiliated with 90 different species were harvested from the reactor exposed to six STM exposures. Gammaproteobacteria (20–31.8%), Bacilli (20–35.7...

MicroRNA-19a and microRNA-19b promote the malignancy of clear cell renal cell carcinoma through targeting the tumor suppressor RhoB

Conceptualization: Xufeng Chen, Xu Zhang. Data curation: Shaoxi Niu. Formal analysis: Shaoxi Niu. Funding acquisition: Xin Ma. Methodology: Yu Zhang. Project administration: Xu Zhang. Resources: Xu Zhang ... . Software: Yen-Nien Liu, Kan Liu. Supervision: Yu Zhang. Validation: Huijie Gong, Yuanxin Yao. Visualization: Kan Liu. Writing ± original draft: Shaoxi Niu. Writing ± review & editing: Yen-Nien Liu

Microbial community response reveals underlying mechanism of industrial-scale manganese sand biofilters used for the simultaneous removal of iron, manganese and ammonia from groundwater

Most studies have employed aeration–biofiltration process for the simultaneous removal of iron, manganese and ammonia in groundwater. However, what’s inside the “black box”, i.e., the potential contribution of functional microorganisms behavior and interactions have seldom been investigated. Moreover, little attention has been paid to the correlations between environmental...

Genome-wide analysis of day/night DNA methylation differences in Populus nigra

set lower because of the complicated relationship between DNA methylation and gene expression. Author Contributions Conceptualization: Bing-Yu Zhang. Data curation: Chang-Jun Ding, Li-Xiong Liang ... , Shu Diao. Formal analysis: Chang-Jun Ding, Li-Xiong Liang, Bing-Yu Zhang. Investigation: Chang-Jun Ding, Li-Xiong Liang. Project administration: Bing-Yu Zhang. Resources: Shu Diao, Xiao-Hua Su

Solid-State Heating Synthesis of Poly (3,4-Ethylenedioxythiophene)/Gold/Graphene Composite and Its Application for Amperometric Determination of Nitrite and Iodate

A ternary composite of poly (3,4-ethylenedioxythiophene)/gold/graphene (PEDOT/Au/GO) for promising electrochemical sensor was synthesized by solid-state heating method. The interaction between the PEDOT, Au, and GO explored for detection of nitrite and iodate. It was found that the PEDOT/Au/GO composite had shale-like morphology with a uniform distribution of gold nanoparticles...

DEC205-DC targeted DNA vaccine against CX3CR1 protects against atherogenesis in mice

. Investigation: Jimmy Jianheng Zhou. Methodology: Jimmy Jianheng Zhou, Yuan Min Wang, Geoff Yu Zhang, Heather Medbury, Helen Williams, Ya Wang, Thian Kui Tan, Stephen I. Alexander, Anne M. Durkan. Project

Diet-derived microRNAs: unicorn or silver bullet?

that otherwise regulation-relevant levels could be reached. Chen-Yu Zhang responds The mobility of small RNA molecules (siRNAs and miRNAs) from one species to another is a newly discovered mechanism for ... experimental functional studies of exogenous miRNA and the most significant challenges to addressing them successfully? Chen-Yu Zhang answers There are two types of “exogenous miRNAs,” including absorbed

Cultivable anaerobic and aerobic bacterial communities in the fermentation chambers of Holotrichia parallela (coleoptera: scarabaeidae) larvae

nutrition and digestion. Author Contributions Data curation: Zhen-yu Zhang, Yongshun Zhao. Formal analysis: Zhen-yu Zhang, Yimin Yuan. Funding acquisition: Hongyu Zhang. Investigation: Tao Peng, Yongshun ... Zhao. Methodology: Yimin Yuan, Yongshun Zhao. Project administration: Yongshun Zhao. Resources: Yimin Yuan, Yongshun Zhao. Software: Zhen-yu Zhang, Wei Peng, Yongshun Zhao. Supervision: Hongyu Zhang

Electrophysiological characteristics of pressure overload-induced cardiac hypertrophy and its influence on ventricular arrhythmias

. Investigation: Weifeng Jiang, Yu Zhang. Resources: Xiaowei Chen, Mu Qin, Weifeng Jiang, Yu Zhang. Supervision: Xu Liu. Writing ± original draft: Xiaowei Chen, Mu Qin. Writing ± review & editing: Xiaowei Chen

Circular RNAs: emerging cancer biomarkers and targets

CircRNAs are a class of RNA molecules that structurally form closed loops. CircRNAs are abundant in eukaryotic transcripts and show certain levels of tissue and cell specificity. CircRNAs have been suggested to regulate gene expression at transcriptional, post-transcriptional, and translational levels. An increasing number of studies have shown that circRNAs play important roles...

The implications of ritual practices and ritual plant uses on nature conservation: a case study among the Naxi in Yunnan Province, Southwest China

Conservation of biodiversity is primary important of today’s critically vulnerable environment. Efficient conservation can be possible only with the long-term participation and understanding of the communities. Ritual beliefs of the indigenous people are one of the important tools to understand the local communities and aid the nature conservation. In this paper, we documented...

Selective medial soft tissue release combined with tibial reduction osteotomy in total knee arthroplasty

To obtain the correct coronal alignment and balancing in flexion and extension, we established a selective medial release technique and investigated the effectiveness and safety of the technique during primary total knee arthroplasty (TKA). Four hundred sixty-six primary TKAs with varus deformity were prospectively evaluated between June 2013 and June 2015. A knee joint position...

Transcriptome analysis of sheep oral mucosa response to Orf virus infection

form of salary for authors Leilei Zhan, Yu Zhang, Yaxun Wei, and Yi Zhang, as well as financial support in the form of research materials. The specific roles of these authors are Introduction ... the members of ABLife Inc for their helpful discussions and critical reading of the manuscript. Author Contributions Data curation: Xiaobing He, Guohua Chen. Formal analysis: Yu Zhang, Yuan Feng

重建歷史想象 : 周穎芳及其彈詞小説《精忠傳》考評

本文從家國危機與女性意識關係的角度考察晚清女作家周穎芳所著長篇彈詞《精忠傳》。通過搜索有關資料、對彈詞文本的解讀及與其他岳飛叙事的比較,考證周穎芳生平及文本中的自我呈現。周以另闢空間的方式在文本中建構了一種對歷史的不同想象,包括從女性視角對岳飛故事的改寫和對傳統家庭角色的重新思考與願景。通過對周穎芳《精忠傳》的重現與解讀,文章重申了對於明清女性文學,尤其女作家創作的叙事文學作品在文學史上的再認識、再探討的重要性。