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Association between serum aluminum levels and cardiothoracic ratio in patients on chronic hemodialysis

the study. (XLSX) Acknowledgments We thank our patients for contributing the dataset to this study. Author Contributions Conceptualization: Yu-Wei Fang. Data curation: Tzu-Lin Wang, Ming-Hsien Tsai ... . Formal analysis: Ming-Hsien Tsai. Investigation: Ming-Hsien Tsai. Methodology: Jyh-Gang Leu, Ming-Hsien Tsai. Supervision: Ming-Hsien Tsai. Validation: Tzu-Lin Wang, Yu-Wei Fang, Ming-Hsien Tsai

SPAK Deficiency Corrects Pseudohypoaldosteronism II Caused by WNK4 Mutation

Stimulation of the OSR1 (Oxidative stress-responsive kinase-1)/SPAK [STE20 (sterile 20)/SPS1-related proline/alanine-rich kinase]-NCC (Na+-Cl− cotransporter) signaling cascade plays an important role in the WNK [With-No-Lysine (K)] kinase 4 D561A knock-in mouse model of pseudohypoaldosteronism type II (PHA II) characterized by salt-sensitive hypertension and hyperkalemia. The aim ...