Advanced search    

Search: authors:"Yuan Yang"

133 papers found.
Use AND, OR, NOT, +word, -word, "long phrase", (parentheses) to fine-tune your search.

A dynamic and multi-responsive porous flexible metal–organic material

. Author information AffiliationsDepartment of Chemical Sciences, Bernal Institute, University of Limerick, Limerick, V94 T9PX, IrelandMohana Shivanna, Qing-Yuan Yang, Alankriti Bajpai, Ewa Patyk-Kazmierczak ...  & Michael J. Zaworotko AuthorsSearch for Mohana Shivanna in:Nature Research journals • PubMed • Google Scholar Search for Qing-Yuan Yang in:Nature Research journals • PubMed • Google Scholar Search for

Optimization of Visual Information Presentation for Visual Prosthesis

, Xi’an 710048, China Correspondence should be addressed to Yuan Yang; moc.qq@1077539 Received 10 November 2017; Revised 26 January 2018; Accepted 7 February 2018; Published 14 March 2018 Academic Editor

A Biologically Inspired Approach to Frequency Domain Feature Extraction for EEG Classification

Classification of electroencephalogram (EEG) signal is important in mental decoding for brain-computer interfaces (BCI). We introduced a feature extraction approach based on frequency domain analysis to improve the classification performance on different mental tasks using single-channel EEG. This biologically inspired method extracts the most discriminative spectral features...

AID/APOBEC-like cytidine deaminases are ancient innate immune mediators in invertebrates

Biomedical Sciences, Chang Gung University, 259 Wenhua 1st Rd, Kwei-Shan District, Tao-Yuan, 333, TaiwanMei-Chen Liu, Wen-Yun Liao, Shu Yuan Yang & Sebastian D. FugmannBiological Sciences, Sunnybrook Research ... Research journals • PubMed • Google Scholar Search for Shu Yuan Yang in:Nature Research journals • PubMed • Google Scholar Search for Jonathan P. Rast in:Nature Research journals • PubMed • Google Scholar

The Role of TLR4 on PGC-1α-Mediated Oxidative Stress in Tubular Cell in Diabetic Kidney Disease

The role and precise mechanism of TLR4 in mitochondria-related oxidative damage and apoptosis of renal tubules in diabetic kidney disease (DKD) remain unclear. We examined the expression of TLR4 in renal biopsy tissues. Db/db diabetic mice and HK-2 cells cultured under high glucose (HG) were used as in vivo and vitro models. Real-time RT-PCR, Western blot, and...

Exosomes secreted by stem cells from human exfoliated deciduous teeth contribute to functional recovery after traumatic brain injury by shifting microglia M1/M2 polarization in rats

Background Traumatic brain injury (TBI) is one of the major causes of mortality and disability for all ages worldwide. Mesenchymal stem cells (MSCs)-originated exosomes have provided therapeutic effects. However, as an indispensable component of MSCs, whether odontogenic stem cell-generated exosomes could benefit TBI is still unclear. Thus we aimed to explore the potential of...

miR-148a-mediated estrogen-induced cholestasis in intrahepatic cholestasis of pregnancy: Role of PXR/MRP3

Intrahepatic cholestasis of pregnancy (ICP) is an idiopathic liver disease while the biochemical characteristic is the elevated level of total bile acid (TBA). The present study investigated whether miR-148a mediates the induced effect of estrogen on the development of ICP and the proper mechanism: PXR/MRP3 signal pathway. mRNA expression was detected by qPCR, protein expression...

Optogenetic Inhibition of Striatal Neuronal Activity Improves the Survival of Transplanted Neural Stem Cells and Neurological Outcomes after Ischemic Stroke in Mice

Meijie Qu,2 Yaying Song,2 Xiaosong He,3 Zhijun Zhang,1 Guo-Yuan Yang,1,2 and Yongting Wang1,4 1Neuroscience and Neuroengineering Research Center, Med-X Research Institute and School of Biomedical ... , Guangzhou Medical University, Guangzhou 510182, China 4Brain Science and Technology Research Center, Shanghai Jiao Tong University, Shanghai, China Correspondence should be addressed to Guo-Yuan Yang; moc

A novel p.Val244Leu mutation in MFN2 leads to Charcot-Marie-Tooth disease type 2

Background Charcot-Marie-Tooth (CMT) disease is one of the most common hereditary peripheral neuropathy. The major clinical features of CMT are progressive muscle weakness of distal extremities and sensory loss. MFN2 encodes a GTPase dynamin-like protein mitofusin 2 and plays an essential role in mitochondrial functions. In previous studies, MFN2 mutations have been linked to...

The effect of early versus late initiation of renal replacement therapy in patients with acute kidney injury: A meta-analysis with trial sequential analysis of randomized controlled trials

Background The optimal timing for initiating renal replacement therapy (RRT) in patients with acute kidney injury (AKI) remains controversial. Methods We conducted a meta-analysis with trial sequential analysis (TSA) of randomized controlled trials (RCTs) using PUBMED, Cochrane Library databases, and Web of Science (from January 1, 1985, to August 21, 2016). Adult patients with...

DEPTOR-mTOR Signaling Is Critical for Lipid Metabolism and Inflammation Homeostasis of Lymphocytes in Human PBMC Culture

Abnormal immune response of the body against substances and tissues causes autoimmune diseases, such as polymyositis, dermatomyositis, and rheumatoid arthritis. Irregular lipid metabolism and inflammation may be a significant cause of autoimmune diseases. Although much progress has been made, mechanisms of initiation and proceeding of metabolic and inflammatory regulation in...

A soft decoding algorithm and hardware implementation for the visual prosthesis based on high order soft demodulation

Background High order modulation and demodulation technology can solve the frequency requirement between the wireless energy transmission and data communication. In order to achieve reliable wireless data communication based on high order modulation technology for visual prosthesis, this work proposed a Reed–Solomon (RS) error correcting code (ECC) circuit on the basis of...

PD-1 blockade restores impaired function of ex vivo expanded CD8+ T cells and enhances apoptosis in mismatch repair deficient EpCAM+PD-L1+ cancer cells

Li,2 Jun Wang,1 Yuan Yang,1,2 Hui-Xin Ge,4 Ping-Sheng Hu,1,2 Jin Xiu1,2 1Clinical Research Centre, The Affiliated Hospital of Guizhou Medical University, Guiyang, People’s Republic of China; 2Cancer

Identification of Palmitoleic Acid Controlled by mTOR Signaling as a Biomarker of Polymyositis

Polymyositis (PM) is a chronic disease characterized by muscle pain, weakness, and increase in muscle-related enzymes, accompanied with inflammations in lymphocytes. However, it is not well understood how the molecular alternations in lymphocytes contribute to the development of polymyositis. The mechanistic target of rapamycin (mTOR) signaling is the central regulator of...

Endothelial progenitor cells transplantation attenuated blood-brain barrier damage after ischemia in diabetic mice via HIF-1α

Background Blood-brain barrier impairment is a major indicator of endothelial dysfunction in diabetes. Studies showed that endothelial progenitor cell (EPC) transplantation promoted angiogenesis and improved function recovery after hind limb ischemia in diabetic mice. The effect of EPC transplantation on blood-brain barrier integrity after cerebral ischemia in diabetic animals is...

A novel fibrillin-1 gene missense mutation associated with neonatal Marfan syndrome: a case report and review of the mutation spectrum

Background Marfan syndrome (MFS) is a heritable disorder of connective tissue resulting from pathogenic variants of the fibrillin-1 gene (FBN1). Neonatal Marfan syndrome (nMFS) is rare and the most severe form of MFS, involving rapidly progressive cardiovascular dysfunction leading to death during early childhood. The constant enrichment of the nMFS mutation spectrum is helpful...

A Novel 3-Input AND/XOR Gate Circuit for Reed-Muller Logic Applications

3-input AND/XOR is the basic complex gate of Reed-Muller logic. Low energy consumption is important for Reed-Muller logic circuit implementation. Against the drawbacks of the published gate-level and transistor-level 3-input AND/XOR gate design in power and power delay product (PDP), a low energy consumption 3-input AND/XOR gate is proposed by employing multi-rails and hybrid...

Development of a Prediction Model Based on RBF Neural Network for Sheet Metal Fixture Locating Layout Design and Optimization

Fixture plays an important part in constraining excessive sheet metal part deformation at machining, assembly, and measuring stages during the whole manufacturing process. However, it is still a difficult and nontrivial task to design and optimize sheet metal fixture locating layout at present because there is always no direct and explicit expression describing sheet metal...