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19 papers found.
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Thyroid hormones associate with risk of incident chronic kidney disease and rapid decline in renal function: a prospective investigation

Background Thyroid hormones have been associated with renal dysfunction in cross-sectional studies. However, prospective studies exploring the effect of thyroid hormones on renal function decline were sparse and got contradictive results. We aimed to prospectively explore the associations of thyroid hormones with incident chronic kidney disease (CKD) and rapid decline in...

Thyroid hormones associate with risk of incident chronic kidney disease and rapid decline in renal function: a prospective investigation

Background Thyroid hormones have been associated with renal dysfunction in cross-sectional studies. However, prospective studies exploring the effect of thyroid hormones on renal function decline were sparse and got contradictive results. We aimed to prospectively explore the associations of thyroid hormones with incident chronic kidney disease (CKD) and rapid decline in...

Geographical Variation in Diabetes Prevalence and Detection in China: Multilevel Spatial Analysis of 98,058 Adults

OBJECTIVE To investigate the geographic variation in diabetes prevalence and detection in China.

Association between carotid intima-media thickness and index of central fat distribution in middle-aged and elderly Chinese

Background Evidence has demonstrated that central fat distribution produces the most profound metabolic abnormalities and is associated with an increased risk of atherosclerotic cardiovascular diseases. We aimed to investigate whether the indexes of central fat distribution, including waist-to-height ratio (WHtR) and visceral fat area (VFA), were stronger risk factors of...

Overexpression of PtSOS2 Enhances Salt Tolerance in Transgenic Poplars

Jie Zhou Jingjing Wang Yufang Bi Like Wang Luozhong Tang Xiang Yu Misato Ohtani Taku Demura Qiang Zhuge 0 ) Key Laboratory of Forest Genetics & Biotechnology , Ministry of Education, Nanjing

Awareness, treatment and control of cardiometabolic disorders in Chinese adults with diabetes: a national representative population study

Background The diagnosis of diabetes has important clinic implications for the prevention and management of cardiometabolic disorders. We aimed to investigate the awareness, treatment and control of hypertension and dyslipidemia in previously-diagnosed and newly-diagnosed diabetes in Chinese adult population. Methods We conducted a cross-sectional survey in a nationally...

Low-Grade Albuminuria Is Associated with Metabolic Syndrome and Its Components in Middle-Aged and Elderly Chinese Population

Background Micro-albuminuria has been well established as one of the risk factors of metabolic syndrome (MetS). However, the association of MetS and its components with low-grade albuminuria among those with normal urinary albumin excretion has not been clearly elucidated in Chinese population. Methodology and Findings A cross-sectional study was conducted among 9,579...

Eosinophil Inversely Associates with Type 2 Diabetes and Insulin Resistance in Chinese Adults

Context Limited population-based study focused on relationship between eosinophil and type 2 diabetes (T2D). Objectives We aimed to evaluate the relationship between peripheral eosinophil percentage and glucose metabolism and insulin resistance in a large sample size of Chinese population aged 40 and older. Design and Methods A cross-sectional study was performed among 9,111...

Circulating Prolactin Associates With Diabetes and Impaired Glucose Regulation: A population-based study

OBJECTIVE Prolactin is a major stimulus for the β-cell adaptation during gestation and guards postpartum women against gestational diabetes. Most studies of the role of prolactin on glucose metabolism have been conducted in humans and animals during pregnancy. However, little is known concerning the association between circulating prolactin and glucose metabolism outside...

Significant Coronary Stenosis in Asymptomatic Chinese With Different Glycemic Status

YU XU YUFANG BI MIAN LI TIANGE WANG KUN SUN MIN XU JIELI LU YI YU XIAOYING LI PHD SHENGHAN LAI WEIQING WANG GUANG NING PHD C a r d i o v a s c u l a r OBJECTIVEd To evaluate coronary artery

Impaired Lung Function Is Associated with Increased Carotid Intima-Media Thickness in Middle-Aged and Elderly Chinese

Background Impairment of lung function was reported to be associated with cardiovascular disease (CVD). The aim of the present study is to evaluate the relationship between lung function and carotid intima-media thickness (cIMT) in participants without chronic pulmonary disease. Methodology and Principal Findings A total of 6,423 participants aged 40 years and above were...

Autonomic Test by EZSCAN in the Screening for Prediabetes and Diabetes

Liu Min Xu Yufang Bi Weiqing Wang Andranik Andrew Aprikyan, Institute for Nanotechnology and Stem Cell Biology, United States of America Background: Autonomic neuropathy is common in diabetics and may

Both Serum Apolipoprotein B and the Apolipoprotein B/Apolipoprotein A-I Ratio Are Associated with Carotid Intima-Media Thickness

Background Previous studies indicated that apolipoprotein measurements predicted cardiovascular disease (CVD) risk; however, associations between apolipoproteins and carotid intima-media thickness (CIMT) were less explored. Methodology and Principal Findings The cross-sectional study included 6069 participants aged 40 years or older with NGT from Shanghai, China. Serum fasting...

Associations of Green Tea and Rock Tea Consumption with Risk of Impaired Fasting Glucose and Impaired Glucose Tolerance in Chinese Men and Women

Objective To explore the associations of green tea and rock tea consumption with risk of impaired fasting glucose (IFG) and impaired glucose tolerance (IGT). Methods A multistage, stratified, cluster, random-sampling method was used to select a representative sample from Fujian Province in China. In total, 4808 subjects without cardiovascular disease, hypertension, cancer, or...

Association Between Higher Serum Fetuin-A Concentrations and Abnormal Albuminuria in Middle-Aged and Elderly Chinese With Normal Glucose Tolerance

OBJECTIVE To study the association of serum fetuin-A as a potential risk factor with abnormal albuminuria in Chinese individuals with normal glucose tolerance (NGT).

Accessing Autonomic Function Can Early Screen Metabolic Syndrome

Background Clinical diagnosis of the metabolic syndrome is time-consuming and invasive. Convenient instruments that do not require laboratory or physical investigation would be useful in early screening individuals at high risk of metabolic syndrome. Examination of the autonomic function can be taken as a directly reference and screening indicator for predicting metabolic...

Serum Fetuin-A Associates with Type 2 Diabetes and Insulin Resistance in Chinese Adults

Background Previous studies have demonstrated that fetuin-A is related to insulin resistance among subjects with normal glucose tolerance but not patients with type 2 diabetes. There are limited data available concerning fetuin-A and insulin resistance in Chinese. We aimed to study the association of feuin-A with insulin resistance among participants with or without type 2...

Combined Effects of 19 Common Variations on Type 2 Diabetes in Chinese: Results from Two Community-Based Studies

Background Many susceptible loci for type 2 diabetes mellitus (T2DM) have recently been identified from Caucasians through genome wide association studies (GWAS). We aimed to determine the association of 11 known loci with T2DM and impaired glucose regulation (IGR), individually and in combination, in Chinese. Methods/Principal Findings Subjects were enrolled in: (1) a case...

A Genome-Wide Association Study Confirms Previously Reported Loci for Type 2 Diabetes in Han Chinese

Background Genome-wide association study (GWAS) has identified more than 30 loci associated with type 2 diabetes (T2D) in Caucasians. However, genomic understanding of T2D in Asians, especially Han Chinese, is still limited. Methods and Principal Findings A two-stage GWAS was performed in Han Chinese from Mainland China. The discovery stage included 793 T2D cases and 806 healthy...