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An iterative approach for the global estimation of sentence similarity

Measuring the similarity between two sentences is often difficult due to their small lexical overlap. Instead of focusing on the sets of features in two given sentences between which we must measure similarity, we propose a sentence similarity method that considers two types of constraints that must be satisfied by all pairs of sentences in a given corpus. Namely, (a) if two ...

Coverage centralities for temporal networks

similar way. tion (http://konect.uni-koblenz.de/). The authors thank Algorithm 3 is an approximate method for computDr. James Cheng for valuable discussions. Yuichi Yoshida ing the centrality value. The

Novel three-sinus enlargement technique for supravalvular aortic stenosis without aortic transection

Background Although repair of a supravalvular aortic stenosis (SVAS) can be performed with low mortality rates, surgery for the complex form of SVAS continues to be associated with a high incidence of residual stenosis. Case presentation The patient was referred to our hospital at 1 month of age and was diagnosed with aortic valve stenosis (AS) by using echocardiography. Cardiac ...

Lipid overloading during liver regeneration causes delayed hepatocyte DNA replication by increasing ER stress in mice with simple hepatic steatosis

Background and aim Impaired fatty liver regeneration has already been reported in many genetic modification models. However, in diet-induced simple hepatic steatosis, which showed similar phenotype with clinical pathology, whether liver regeneration is impaired or not remains unclear. In this study, we evaluated liver regeneration in mice with diet-induced simple hepatic steatosis, ...

N-Acetylglucosaminyltransferase V regulates TGF-β response in hepatic stellate cells and the progression of steatohepatitis

N-Acetylglucosaminyltransferase V (GnT-V), catalyzing β1-6 branching in asparagine-linked oligosaccharides, is one of the most important glycosyltransferases involved in tumor metastasis and carcinogenesis. Although the expression of GnT-V is induced in chronic liver diseases, the biological meaning of GnT-V in the diseases remains unknown. The aim of this study was to investigate ...

Serum Fucosylated Haptoglobin as a Novel Diagnostic Biomarker for Predicting Hepatocyte Ballooning and Nonalcoholic Steatohepatitis

Nonalcoholic fatty liver disease (NAFLD) is a growing medical problem around the world. NAFLD patients with nonalcoholic steatohepatitis (NASH) can develop cirrhosis and hepatocellular carcinoma. The ability to distinguish NASH from simple steatosis would be of great clinical significance. Ballooning hepatocytes are characteristic of typical pathological NASH; here, the polarized ...

Anaemia

Introduction and Aims: Peginesatide is a PEGylated, investigational, peptide-based erythropoiesis stimulating agent that is designed to specifically stimulate the EPOR and is currently being developed for the treatment of anemia of chronic kidney disease in dialysis patients. The peginesatide peptide has a unique structure with no sequence similarity to erythropoietin. This study ...