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32 papers found.
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Giant graviton interactions and M2-branes ending on multiple M5-branes

AbstractWe study splitting and joining interactions of giant gravitons with angular momenta N 1/2 ≪ J ≪ N in the type IIB string theory on AdS5 × S5 by describing them as instantons in the tiny graviton matrix model introduced by Sheikh-Jabbari. At large J the instanton equation can be mapped to the four-dimensional Laplace equation and the Coulomb potential for m point charges...

Resident fibroblasts in the kidney: a major driver of fibrosis and inflammation

Background Chronic kidney disease (CKD) is a leading cause of end stage renal disease (ESRD) and cardiovascular morbidity and mortality worldwide, resulting in a growing social and economic burden. The prevalence and burden of CKD is anticipated to further increase over the next decades as a result of aging. Main body of abstract In the pathogenesis of CKD, irrespective of the...

Year-Round Performance of a Passive Sulfate-Reducing Bioreactor that Uses Rice Bran as an Organic Carbon Source to Treat Acid Mine Drainage

The development of compact and cost-effective passive treatment systems is of critical importance for acid mine drainage (AMD) remediation in Japan. The purpose of this study was to construct an AMD treatment system comprising a sulfate-reducing bioreactor using rice bran as a carbon source for sulfate-reducing bacteria (SRB) and to demonstrate its stable operation for at least a...

Hydraulic retention time and pH affect the performance and microbial communities of passive bioreactors for treatment of acid mine drainage

For acceleration of removing toxic metals from acid mine drainage (AMD), the effects of hydraulic retention time (HRT) and pH on the reactor performance and microbial community structure in the depth direction of a laboratory-scale packed-bed bioreactor containing rice bran as waste organic material were investigated. The HRT was shortened stepwise from 25 to 12 h, 8 h, and 6 to...

Constraint algebra of general relativity from a formal continuum limit of canonical tensor model

Canonical tensor model (CTM for short below) is a rank-three tensor model formulated as a totally constrained system in the canonical formalism. In the classical case, the constraints form a first-class constraint Poisson algebra with structures similar to that of the ADM formalism of general relativity, qualifying CTM as a possible discrete formalism for quantum gravity. In this...

Baseline serum syndecan-4 predicts prognosis after the onset of acute exacerbation of idiopathic interstitial pneumonia

Background Patients with idiopathic interstitial pneumonia can experience acute respiratory worsening, also known as acute exacerbation, with a large deterioration on prognosis. The precise mechanism remains unclear; however, syndecan-4 may be involved. Syndecan-4, a transmembrane heparan sulfate proteoglycan expressed in a variety of cells (e.g., epithelial cells, macrophages...

Renormalization procedure for random tensor networks and the canonical tensor model

We discuss a renormalization procedure for random tensor networks, and show that the corresponding renormalization-group flow is given by the Hamiltonian vector flow of the canonical tensor model, which is a discretized model of quantum gravity. The result is a generalization of the previous one concerning the relation between the Ising model on random networks and the canonical...

On membrane interactions and a three-dimensional analog of Riemann surfaces

Membranes in M-theory are expected to interact via splitting and joining processes. We study these effects in the pp-wave matrix model, in which they are associated with transitions between states in sectors built on vacua with different numbers of membranes. Transition amplitudes between such states receive contributions from BPS instanton configurations interpolating between...

Ising model on random networks and the canonical tensor model

We introduce a statistical system on random networks of trivalent vertices for the purpose of studying the canonical tensor model, which is a rank-three tensor model in the canonical formalism. The partition function of the statistical system has a concise expression in terms of integrals, and has the same symmetries as the kinematical ones of the canonical tensor model. We...

Characteristics and Prognostic Impact of Pneumonitis during Systemic Anti-Cancer Therapy in Patients with Advanced Non-Small-Cell Lung Cancer

Background Data on characteristics, outcomes, and prognosis of advanced non-small-cell lung cancer (NSCLC) patients who develop pneumonitis during systemic anti-cancer therapy (pneumonitis) are currently lacking. Methods We conducted a retrospective cohort study of 910 consecutive patients diagnosed with advanced NSCLC between January 2004 and January 2014. Of these, 140 patients...

Physical states in the canonical tensor model from the perspective of random tensor networks

Tensor models, generalization of matrix models, are studied aiming for quantum gravity in dimensions larger than two. Among them, the canonical tensor model is formulated as a totally constrained system with first-class constraints, the algebra of which resembles the Dirac algebra of general relativity. When quantized, the physical states are defined to be vanished by the...

Membranes from monopole operators in ABJM theory: Large angular momentum and M-theoretic AdS4/CFT3

We study the duality between M-theory in AdS$_4 \times S^7/\mathbb {Z}_k$ and the ABJM $\mathcal {N}=6$ Chern–Simons-matter theory with gauge group U($N) \times \hbox {U}(N$) and level $k$, taking $N$ large and $k$ of order 1. In this M-theoretic regime the lack of an explicit formulation of M-theory in AdS$_4 \times S^7/\mathbb {Z}_k$ makes the gravity side difficult, while the...

The prognostic value of serum CA 19-9 for patients with advanced lung adenocarcinoma

Background This study aimed to assess the prognostic accuracy of serum CA 19-9 in patients with advanced lung adenocarcinoma. Methods We retrospectively reviewed data of 246 patients who were diagnosed at our institute with advanced (stage IIIB or IV) lung adenocarcinoma between March 2006 and December 2012. We excluded patients who received no chemotherapy, or for whom we had no...

Bio-Augmentation of Cupriavidus sp. CY-1 into 2,4-D Contaminated Soil: Microbial Community Analysis by Culture Dependent and Independent Techniques

In the present study, a 2,4-dichlorophenoxyacetic acid (2,4-D) degrading bacterial strain CY-1 was isolated from the forest soil. Based on physiological, biochemical and 16S rRNA gene sequence analysis it was identified as Cupriavidus sp. CY-1. Further 2,4-D degradation experiments at different concentrations (200 to 800 mg l-1) were carried out using CY-1. Effect of NaCl and...

Thioredoxin-Interacting Protein Gene Expression via MondoA Is Rapidly and Transiently Suppressed during Inflammatory Responses

Whereas accumulating evidence indicates that a number of inflammatory genes are induced by activation of nuclear factor-κB and other transcription factors, less is known about genes that are suppressed by proinflammatory stimuli. Here we show that expression of thioredoxin-interacting protein (Txnip) is dramatically suppressed both in mRNA and protein levels upon stimulation with...

Serum Syndecan-4 as a Possible Biomarker in Patients With Acute Pneumonia

Background. Syndecan-4 is a transmembrane heparan sulfate proteoglycan expressed in a variety of cells, and glycosaminoglycan side chains of syndecan-4 bind to several proteins, suggesting several biological functions. However, the role of syndecan-4 in acute bacterial pneumonia has not yet been elucidated. Methods. Serum syndecan-4 levels were measured in patients with acute...

Airway obstruction by a retropharyngeal hematoma secondary to thoracic aortic aneurysm rupture

Background Retropharyngeal hematoma is a rare form of pharyngeal pathology and can present as acute airway obstruction. Among the many causes of retropharyngeal hematoma, thoracic aortic rupture is extremely rare. Methods and results A 78-year-old female with airway obstruction by a retropharyngeal hematoma secondary to thoracic aortic aneurysm rupture was successfully treated by...

Inhibitory Effects of Azelnidipine Tablets on Morning Hypertension

Background Morning hypertension is a risk factor for cardiovascular and cerebrovascular events. Furthermore, it is a useful measure for definitive diagnosis of hypertension, and patients who self-assess their own blood pressure (BP) in the morning tend to exhibit better compliance with antihypertensive medication than those who do not. Objective The objective of this analysis was...