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Apatinib-treated advanced medullary thyroid carcinoma: a case report

Apatinib-treated advanced medullary thyroid carcinoma: a case report Kan Chen, Yun Gao, Fei Shi, Guangqiang Cao, Jiandong Bao Key Laboratory of Nuclear Medicine, Ministry of Health, Jiangsu Key

Single-cell RNA-seq uncovers dynamic processes and critical regulators in mouse spermatogenesis

equally: Yao Chen, Yuxuan Zheng, Yun Gao, Zhen Lin, Suming Yang. AffiliationsState Key Laboratory of Molecular Biology, Shanghai Key Laboratory of Molecular Andrology, CAS Center for Excellence in Molecular ... University, Beijing, 100871, ChinaYuxuan Zheng, Yun Gao & Fuchou TangMinistry of Education Key Laboratory of Cell Proliferation and Differentiation, Beijing, 100871, ChinaYuxuan Zheng, Yun Gao & Fuchou

Vitamin D and Incidence of Prediabetes or Type 2 Diabetes: A Four-Year Follow-Up Community-Based Study

January 2018; Published 18 March 2018 Academic Editor: Hubertus Himmerich Copyright © 2018 Yun Gao et al. This is an open access article distributed under the Creative Commons Attribution License, which ... ’ Contributions Yun Gao and Tianpeng Zheng performed the statistical analysis and prepared the manuscript. Haoming Tian was responsible for the study design and coordination, guided the statistical analysis, and

Antimicrobial mechanism of theaflavins: They target 1-deoxy-D-xylulose 5-phosphate reductoisomerase, the key enzyme of the MEP terpenoid biosynthetic pathway

, Dan-Dan Zhang, Heng Li, Shao-Qing Yang & Wen-Yun Gao AuthorsSearch for Xian Hui in:Nature Research journals • PubMed • Google ScholarSearch for Qiao Yue in:Nature Research journals • PubMed • Google ... • PubMed • Google ScholarSearch for Wen-Yun Gao in:Nature Research journals • PubMed • Google Scholar Contributions X.H., Q.Y., and H.L. measured inhibitory activities of the theaflavins against DXR and

Toughness Condition for a Graph to Be a Fractional -Critical Deleted Graph

Copyright © 2014 Wei Gao and Yun Gao. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium

Influence of Concrete Properties on Molten Core-Concrete Interaction: A Simulation Study

In a severe nuclear power plant accident, the molten core can be released into the reactor pit and interact with sacrificial concrete. In this paper, a simulation study is presented that aims to address the influence of sacrificial concrete properties on molten core-concrete interaction (MCCI). In particular, based on the MELCOR Code, the ferrosiliceous concrete used in European...

Factors affecting the yield of bio-oil from the pyrolysis of coconut shell

Coconut is a high-quality agricultural product of the Asia–Pacific region. In this paper, coconut shell which mainly composed of cellulose, hemicellulose, lignin was used as a raw material for coconut shell oil from coconut shell pyrolysis. The influence of the pyrolysis temperature, heating rate and particle size on coconut oil yield was investigated, and the effect of heating...

On Jacobsthal and Jacobsthal-Lucas Circulant Type Matrices

Circulant type matrices have become an important tool in solving fractional order differential equations. In this paper, we consider the circulant and left circulant and -circulant matrices with the Jacobsthal and Jacobsthal-Lucas numbers. First, we discuss the invertibility of the circulant matrix and present the determinant and the inverse matrix. Furthermore, the invertibility...

Establishment of a γ-H2AX foci-based assay to determine biological dose of radon to red bone marrow in rats

Wang, Defang Ding, Yun Gao, Xuxia Zhang, Qiang Li & Honghong ChenDepartment of Radiology, Ningbo Medical Center, Lihuili Eastern Hospital, Ningbo 315100, Zhejiang, ChinaJing WangDivision of Ionizing ... Defang Ding in:Nature Research journals • PubMed • Google ScholarSearch for Xufei Wang in:Nature Research journals • PubMed • Google ScholarSearch for Yun Gao in:Nature Research journals • PubMed • Google

The Role of miR-34a in the Hepatoprotective Effect of Hydrogen Sulfide on Ischemia/Reperfusion Injury in Young and Old Rats

Hydrogen sulfide (H2S) can protect the liver against ischemia-reperfusion (I/R) injury. However, it is unknown whether H2S plays a role in the protection of hepatic I/R injury in both young and old patients. This study compared the protective effects of H2S in a rat model (young and old animals) of I/R injury and the mechanism underlying its effects. Young and old rats were...

Genome-Wide De Novo Prediction of Cis-Regulatory Binding Sites in Mycobacterium tuberculosis H37Rv

The transcription regulatory system of Mycobacterium tuberculosis (M. tb) remains incompletely understood. In this study, we have applied the eGLECLUBS algorithm to a group of related prokaryotic genomes for de novo genome-wide prediction of cis-regulatory binding sites (CRBSs) in M. tb H37Rv. The top 250 clusters from our prediction recovered 83.3% (50/60) of all known CRBSs in...

Silibinin down-regulates FAT10 and modulate TNF-α/IFN-γ-induced chromosomal instability and apoptosis sensitivity

Pleiotropic pro-inflammatory cytokines, TNF-α and IFN-γ (TI), play important yet diverse roles in cell survival, proliferation, and death. Recent evidence highlights FAT10 as a downstream molecule in the pathway of inflammation-induced tumorigenesis through mediating the effect of cytokines in causing numerical CIN and protecting cells from cytokines-induced cell death. cDNA...

Synthesis and Characteristics of FePt Nanoparticle Films Under In Situ-Applied Magnetic Field

In situ external magnetic field was applied during the synthesis of FePt nanoparticles via a chemical solution method. FePt nanoparticle films were prepared on Si by a drop-coating method with and without a magnetic field. Annealing at 700 °C in reductive atmosphere was explored to obtain ferromagnetic FePt L10 phase. The effect of in situ-applied magnetic field on the structure...

Wiener Index of Graphs and Their Line Graphs

Xiaohai Su Ligong Wang Yun Gao The Wiener index W (G) of a graph G is a distance-based topological index defined as the sum of distances between all pairs of vertices in G. It is shown that for

Genetic variations associated with six-white-point coat pigmentation in Diannan small-ear pigs

, Xu-Man Han, Yun-Fei Ma, David M. Irwin, Yun Gao, Jia-Kun Deng, Adeniyi C. Adeola, Hai-Bing Xie & Ya-Ping ZhangKunming College of Life Science, University of Chinese Academy of Sciences, Kunming ... journals • PubMed • Google ScholarSearch for Yun-Fei Ma in:Nature Research journals • PubMed • Google ScholarSearch for David M. Irwin in:Nature Research journals • PubMed • Google ScholarSearch for Yun Gao

Inhibition of MTA1 by ERα contributes to protection hepatocellular carcinoma from tumor proliferation and metastasis

Background Although expression of MTA1 inversely correlates with the nuclear localization of ERα, the effect and molecular mechanism of ERα regulation of MTA1 remain unknown. Methods Quantitative real-time PCR and western blot analyses were used to measure levels of MTA1. The effect on HCC cell proliferation and invasion was assessed by EdU incorporation assays and Transwell...

Novel germline mutations and unclassified variants of BRCA1 and BRCA2 genes in Chinese women with familial breast/ovarian cancer

Background Germline mutations in the BRCA1 and BRCA2 genes greatly increase a woman’s risk of developing breast and/or ovarian cancer. The prevalence and distribution of such mutations differ across races/ethnicities. Several studies have investigated Chinese women with high-risk breast cancer, but the full spectrum of the mutations in these two genes remains unclear. Methods In...

The clinical pathological characteristics and prognosis of FGFR1 gene amplification in non-small-cell lung cancer: a meta-analysis

The clinical pathological characteristics and prognosis of FGFR1 gene amplification in non-small-cell lung cancer: a meta-analysis Fa-Jun Xie,1,2 Hong-Yang Lu,1,3 Qiu-Qing Zheng,3 Jing Qin,1,3 Yun