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Special issue on resilience in steel structures

Structures”. Guest Editors Wei Wang Professor, Tongji University, China E-mail: Tak-Ming Chan Assistant Professor, The Hong Kong Polytechnic University, Hong Kong SAR, China Yunfeng Zhang Professor, University

A Novel Canine Model of Acute Vertebral Artery Occlusion

Background The extended time window and theoretic reduction in hemorrhage make mechanical strategies an attractive approach for the treatment of patients with ischemic stroke. However, a limited availability of suitable animal models of cerebrovascular thrombosis has hampered the study of novel endovascular interventions. The aim of the present study was to develop a new technique ...

The Downregulation of MiR-182 Is Associated with the Growth and Invasion of Osteosarcoma Cells through the Regulation of TIAM1 Expression

Background Osteosarcoma is the most common primary bone malignancy in children and young adults. Increasing results suggest that discovery of microRNAs (miRNAs) might provide a novel therapeutical target for osteosarcoma. Methods MiR-182 expression level in osteosarcoma cell lines and tissues were assayed by qRT-PCR. MiRNA mimics or inhibitor were transfected for up-regulation or ...

Mode-of-disparities error correction of eye-tracking data

Yunfeng Zhang Anthony J. Hornof In eye-tracking research, there is almost always a disparity between a person's actual gaze location and the location recorded by the eye tracker. Disparities that

Zinc reverses glycine-dependent inactivation of NMDARs in cultured rat hippocampal neurons

In the presence of glutamate and co-agonists, e.g., glycine, the N-methyl-D-aspartate receptor (NMDAR) plays an important role in physiological and pathophysiological brain processes. Previous studies indicate glycine could inhibit NMDAR responses induced by high concentration of NMDA in hippocampal neurons. The mechanism underlying this inhibitory impact, however, has been ...

Fabrication of a proton exchange membrane via blended sulfonimide functionalized polyamide

A novel linear non-fluorinated sulfonimide functionalized polyamide (SPA) polymer electrolyte was successfully synthesized via an aromatic sulfonimide monomer with superior thermal stability and superacidity. The aromatic sulfonimide remains stable below 220 °C. To fabricate membranes with strong mechanical strength and dimensional stability, the polymer was blended with various ...

Corticothalamic Feedback for Sound-Specific Plasticity of Auditory Thalamic Neurons Elicited by Tones Paired with Basal Forebrain Stimulation

Recent studies have revealed that the auditory cortex (AC) plays a crucial role in the plastic changes in the physiological properties of subcortical auditory neurons through corticofugal projections. In this study with the C57 mouse, we investigated the receptive field plasticity of the ventral division of the medial geniculate body (MGBv) of the thalamus and the impact of the ...

Design and implementation of the first nationwide, web-based Chinese Renal Data System (CNRDS)

Background In April 2010, with an endorsement from the Ministry of Health of the People's Republic of China, the Chinese Society of Nephrology launched the first nationwide, web-based prospective renal data registration platform, the Chinese Renal Data System (CNRDS), to collect structured demographic, clinical, and laboratory data for dialysis cases, as well as to establish a ...

Multiparametric Changes in the Receptive Field of Cortical Auditory Neurons Induced by Thalamic Activation in the Mouse

The functional organization of the sensory cortex is constructed to process sensory information based on experience and learning. Importantly, it is plastic so that it can quickly adapt to environmental changes. Because the thalamus gates all ascending information, it is critical to understand how the thalamocortical system contributes to the plasticity of the sensory cortex. We ...

Decreased Input-Specific Plasticity of the Auditory Cortex in Mice Lacking M1 Muscarinic Acetylcholine Receptors

Muscarinic acetylcholine receptors are extensively involved in cortical cognition and learning-induced or experience-dependent cortical plasticity. The most abundant muscarinic receptor subtype in the cerebral cortex is the M1 receptor, but little is known about its contribution to experience-dependent plasticity of the adult auditory cortex. We have examined the role of the M1 ...