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Search: authors:"Yunhui Li"

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CDK-mediated RNF4 phosphorylation regulates homologous recombination in S-phase

There are the two major pathways responsible for the repair of DNA double-strand breaks (DSBs): non-homologous end-joining (NHEJ) and homologous recombination (HR). NHEJ operates throughout the cell-cycle, while HR is primarily active in the S/G2 phases suggesting that there are cell cycle-specific mechanisms that regulate the balance between NHEJ and HR. Here we reported that...

Association between IL-10 Gene Polymorphisms and Susceptibility of Tuberculosis: Evidence Based on a Meta-Analysis

Background A number of observational studies have been conducted to investigate the association of IL-10 gene polymorphisms with tuberculosis (TB) susceptibility. However, the results of different studies were inconsistent. The aim of this study was to investigate the relationship between IL-10 -1082G/A, -819T/C, and -592A/C polymorphisms and TB risk by meta-analysis. Methods A...

Serum Vascular Endothelial Growth Factor (VEGF-C) as a Diagnostic and Prognostic Marker in Patients with Ovarian Cancer

VEGF-C is regarded as one of the most efficient factors in regulating lymphangiogenesis. The aim of this study was to better understand the role of VEGF-C in the progression of ovarian cancer and to assess its diagnostic and prognostic significance. A total of 109 patients with ovarian cancer, 76 patients with benign ovarian diseases, and 50 healthy controls were recruited in...

Prognostic value of serum paraoxonase and arylesterase activity in patients with sepsis

Objective To determine whether serum paraoxonase (PON) and arylesterase (ARE) activity might predict sepsis mortality.

HERC2-USP20 axis regulates DNA damage checkpoint through Claspin

The DNA damage response triggers cell-cycle checkpoints, DNA repair and apoptosis using multiple post-translational modifications as molecular switches. However, how ubiquitination regulates ATR signaling in response to replication stress and single-strand break is still unclear. Here, we identified the deubiquitination enzyme (DUB) USP20 as a pivotal regulator of ATR-related DDR...

Positive solutions of boundary value problem for singular positone and semi-positone third-order difference equations

This article studies the boundary value problems for the third-order nonlinear singular difference equations satisfying five kinds of different boundary value conditions. This article shows the existence of positive solutions for positone and semi-positone type. The nonlinear term may be singular. Two examples are also given to illustrate the main results. The arguments are based...

Positive solutions of boundary value problem for singular positone and semi-positone third-order difference equations

This article studies the boundary value problems for the third-order nonlinear singular difference equations Δ 3 u ( i - 2 ) + λ a ( i ) f ( i , u ( i ) ) = 0 , i ∈ [ 2 , T + 2 ] , satisfying five kinds of different boundary value conditions. This article shows the existence of positive solutions for positone and semi-positone type. The nonlinear term may be singular. Two...

ABO Blood Group and Incidence of Skin Cancer

Background Previous studies have examined the association between ABO blood group and the risk of some malignancies. However, no prospective cohort study to date has examined the association between ABO blood group and the risk of skin cancer. Methodology/Principal Findings Using two large cohorts in the US, we examined ABO blood type and incidence of skin cancer, including...

Transcriptional regulation of ethylene receptor and CTR genes involved in ethylene-induced flower opening in cut rose (Rosa hybrida) cv. Samantha

In this work, the effect of ethylene on flower opening of cut rose (Rosa hybrida) cv. Samantha was studied. However, although ethylene hastened the process of flower opening, 1-MCP (1-methylcyclopropene), an ethylene action inhibitor, impeded it. Ethylene promoted ethylene production in petals, but 1-MCP did not inhibit this process. Of the four ethylene biosynthetic genes tested...