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6 papers found.
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Determination of an effective scoring function for RNA–RNA interactions with a physics-based double-iterative method

RNA–RNA interactions play fundamental roles in gene and cell regulation. Therefore, accurate prediction of RNA–RNA interactions is critical to determine their complex structures and understand the molecular mechanism of the interactions. Here, we have developed a physics-based double-iterative strategy to determine the effective potentials for RNA–RNA interactions based on a...

Optimization on the Law of Variable-Pitch Vertical-Axis Tidal Current Turbine

In order to improve the hydrodynamic performance of the vertical-axis variable-pitch current turbine, with analyzing on the existing design mentality of blade control mechanism, an optimized law of variable-pitch vertical-axis tidal current turbine was given in terms of the instantaneous moment coefficient of the blade. A method for solving the lift - drag coefficient of Blade by...

Adiponectin Exerts Neurotrophic Effects on Dendritic Arborization, Spinogenesis, and Neurogenesis of the Dentate Gyrus of Male Mice

The hippocampus, a brain region critical for learning, memory and emotional processing, maintains its capacity to undergo structural plasticity throughout life. Hippocampal structural plasticity can be modulated by a number of intrinsic and extrinsic factors. This study investigated the effects of adiponectin, an adipocyte-derived hormone, on dendritic growth, arborization, and...

Mitogen-Activated Protein Kinase 8 (MAP3K8) Mediates the Signaling Pathway of Estradiol Stimulating Progesterone Production Through G Protein-Coupled Receptor 30 (GPR30) in Mouse Corpus Luteum

The corpus luteum (CL) is a transient endocrine gland developed from the ovulated follicles, and the most important function is to synthesize and secrete progesterone (P4), a key hormone to maintain normal pregnancy and estrous cycle in most mammals. It is known that estrogen has a vital role in stimulating P4 synthesis in CL, but it still remains unclear about the mechanism of...

Expression of delta-catenin is associated with progression of human astrocytoma

Background δ-Catenin (CTNND2), which encodes a scaffold protein in humans, has been found in a few malignancies. However, the expression pattern and contribution of δ-catenin to astrocytoma progression are unclear. Methods We investigated δ-catenin expression in human astrocytoma samples and its function in astrocytoma cell lines using immunohistochemistry, siRNA knockdown...