This study aimed to verify the accuracy of intraoperative femurofibular angle combined with tibiofibular angle (FFA–TFA) measurement and compare it with traditional alignment line methods in open-wedge high tibial osteotomy (OWHTO). A total of 174 knees of 122 patients undergoing OWHTO and using an alignment line or FFA–TFA measurement as an index of optimal correction were...
The aim of this study was to assess the accuracy and test-retest reliability of a wearable inertial measurement unit (IMU) system for gait analysis in healthy female compared to a gold-standard optoelectronic motion capture (OMC) system. In our study, we collected data from 5 healthy young females. Participants were attached with markers from both the OMC system and the IMU...
HER2-positive (HER2+) metastatic breast cancer (mBC) is highly aggressive and a major threat to human health. Despite the significant improvement in patients’ prognosis given the drug development efforts during the past several decades, many clinical questions still remain to be addressed such as efficacy when combining different therapeutic modalities, best treatment sequences...
Mushrooms have been utilized by humans for thousands of years due to their medicinal and nutritional properties. They are a crucial natural source of bioactive secondary metabolites, and recent advancements have led to the isolation of several alkynyl-containing compounds with potential medicinal uses. Despite their relatively low abundance, naturally occurring alkynyl compounds...
Buffer overflow poses a serious threat to the memory security of modern operating systems. It overwrites the contents of other memory areas by breaking through the buffer capacity limit, destroys the system execution environment, and provides implementation space for various system attacks such as program control flow hijacking. That makes it a wide range of harms. A variety of...
Organosilanes possessing an enantioenriched stereogenic silicon center are important in many branches of chemistry, yet they remain challenging to synthesize in a practical and scalable way. Here we report a dynamic kinetic silyletherification process of racemic chlorosilanes with (S)-lactates using 4-aminopyridine as a Lewis base catalyst. This enantioconvergent approach...
experimental support. Author Contributions Conceptualization: Abdallah Ghonimy, Jian Li. Data curation: Zhao Chen. Funding acquisition: Jian Li. Investigation: Abdallah Ghonimy. Methodology: Abdallah
Lung ischemia/reperfusion injury (LIRI) is a complex pathophysiological process, with the histopathological hallmark of neutrophils migrating into the lungs. Neutrophil extracellular traps (NETs) have been suggested to exert a critical role in the pathogenesis of inflammation and infection in humans and animals, while the exact functions and underlying mechanisms of NETs in LIRI...
The hippocampus plays major roles in learning and memory, and its formation requires precise coordination of patterning, cell proliferation, differentiation, and migration. Here we removed the chromatin-association capability of KDM2B in the progenitors of developing dorsal telencephalon (Kdm2b∆CxxC) to discover that Kdm2b∆CxxC hippocampus, particularly the dentate gyrus, became...
Lu). We will also record the reasons for excluding irrelevant RCTs. Any disagreements will be settled by a third researcher (Zhao Chen). Fig 1 illustrates the study selection process. Risk of bias ... ) Supporting information Author Contributions Conceptualization: Rui Cao, Zhao Chen. Investigation: Rui Cao, Jiaxing Lu. Supervision: Zhao Chen. Writing – original draft: Rui Cao. Writing – review
Previous studies reported mixed findings on autistic individuals’ pitch perception relative to neurotypical (NT) individuals. We investigated whether this may be partly due to individual differences in cognitive abilities by comparing their performance on various pitch perception tasks on a large sample (n = 164) of autistic and NT children and adults. Our findings revealed that...
Deep learning (DL) has attracted tremendous interest in various fields in last few years. Convolutional neural networks (CNNs) based DL architectures have been successfully applied in computer vision, medical image processing, remote sensing, and many other fields. A recent work has proved that CNNs based models can also be used to handle geophysical problems. Due to noises in...
projection; Risk factor; Adverse events; Safety; Ribavirin; Age; Severity; Herb-drug interaction - †Rui Zheng and Zhao Chen are Co-first authors Introduction Xiyanping injection (XYP) is a commonly used
We aim to introduce a method using confocal scanning laser ophthalmoscopy (cSLO) images for measuring retinal vascular geometry, including vessel branch angle (BA), vessel diameter, vessel tortuosity, and fractal dimension (Df), and to elucidate the relationship between hypertension and these metrics. A total of 119 participants (119 eyes) were enrolled, among which 72 were...
Orbital [99mTc]TcDTPA orbital single-photon emission computed tomography (SPECT)/CT is an important method for assessing inflammatory activity in patients with Graves’ orbitopathy (GO). However, interpreting the results requires substantial physician workload. We aim to propose an automated method called GO-Net to detect inflammatory activity in patients with GO. GO-Net had two...
Introducing oxygen-vacancy into the surface of the non-enzymatic sensor is supposed to be an effective way to improve inherently low catalytic activity and specificity of non-enzymatic sensors. In this work, CuO/C was synthesized at different temperatures using metal-organic frameworks as sacrificial templates to receive additional content of oxygen-vacancy. The product with the...
The diagnosis of periprosthetic joint infection (PJI) remains a challenge in clinical practice. Many novel serum and joint fluid biomarkers have important implications for the diagnosis of PJI. The presented study evaluated the value of joint fluid interleukin-6 (IL-6) combined with the neutral polymorphonuclear leukocyte (PMN%) ratio for chronic PJI diagnosis after arthroplasty...
Psoralea corylifolia is a medicinal leguminous plant that has long been used to treat various diseases. Psoralidin (PSO) is the main extract compound of P. corylifolia and exhibits antibacterial, antitumor, anti-inflammatory, antioxidant, and other pharmacological activities. PSO has demonstrated inhibitory effects in several cancers; however, its inhibitory effect on...
