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Is exclusion of leukocytes from platelet-rich plasma (PRP) a better choice for early intervertebral disc regeneration?

BackgroundPlatelet-rich plasma (PRP) is becoming a promising strategy to treat early intervertebral disc degeneration (IDD) in clinics. Pure PRP without leukocytes (P-PRP) may decrease the catabolic and inflammatory changes in the early degenerated intervertebral discs. The aim of this study was to investigate the effects of P-PRP on nucleus pulposus-derived stem cells (NPSCs...

Is there a problem with quantum models of psychological measurements?

and AFOSR FA9550-15-10343. Author Contributions Conceptualization: Jerome Busemeyer, Zheng Wang. Data curation: Zheng Wang. Formal analysis: Jerome Busemeyer. Funding acquisition: Jerome Busemeyer ... , Zheng Wang. Methodology: Zheng Wang. Writing ± original draft: Jerome Busemeyer, Zheng Wang. Writing ± review & editing: Zheng Wang. 1. Gudder S. P. Quantum Probability . Academic Press, 1988 . 2

The Evaluation Method for Operation Efficiency of Equipment System Based on Data Farming and Mining

Through process data and results data resulted from operation efficiency simulation of equipment system, based on information measure criteria, data farming and mining method is used. Final simulation results are provided against specific models and verification is carried out on the internal relationships of equipment system and the effectiveness of equipment tactics capability...

Examining drivers of the emissions embodied in trade

Emissions embodied in provincial trade (EEPT) have important effects on provinces’ responsibilities for carbon emission reductions. Based on a multi-regional input-output model, we calculated EEPT for China’s 30 provinces in 2002, 2007 and 2010, and we attempted to determine the drivers of EEPT. The results showed that, during this period, the ratio of EEPT to production-based...

Cognitive Fusion of Thermal and Visible Imagery for Effective Detection and Tracking of Pedestrians in Videos

In this paper, we present an efficient framework to cognitively detect and track salient objects from videos. In general, colored visible image in red-green-blue (RGB) has better distinguishability in human visual perception, yet it suffers from the effect of illumination noise and shadows. On the contrary, the thermal image is less sensitive to these noise effects though its...

A cross-sectional study of inpatients with late stage of dementia in Southeast China and the associations between biochemical parameters and apolipoprotein E genotypes

,3,* Mei-Fang Chen,3 Zheng Wang,3 Ming-Xue Zhao,3 Bin-Hua Chen,3 Hong-Lei Li1 1Department of Neurology and Research Center of Neurology, The Second Affiliated Hospital of Zhejiang University School of

Application of JC1 for non-toxic isolation of cells with MDR transporter activity by flow cytometry

The DNA intercalating dye Hoechst 33342 or its close analog DCV are actively removed from cells by the multidrug resistance transporter ABCG2, a protein overexpressed in metastatic cells and somatic stem cells. In bivariate blue-red flow cytometry fluorescent plots active Hoechst or DCV efflux combined with a concentration dependent bathochromic shifts of these nuclear dyes leads...

First experience of robotic spleen-preserving distal pancreatectomy in a child with insulinoma

An insulinoma is a functional neuroendocrine pancreatic tumor, and surgical resection is indicated. Robot-assisted laparoscopic surgeries have been shown to be generally safe and feasible for treatment of pediatric cases of urologic and digestive disease. In July 2016, a 9-year-old girl (24 kg, 120 cm) was admitted with a pancreatic tail insulinoma and underwent robot-assisted...

Serum exosomal miR-125b is a novel prognostic marker for hepatocellular carcinoma

Serum exosomal miR-125b is a novel prognostic marker for hepatocellular carcinoma Weifeng Liu,1–3,* Jie Hu,1,2,* Kaiqian Zhou,1,2,* Feiyu Chen,1,2 Zheng Wang,1,2 Boyi Liao,1,2 Zhi Dai,1,2 Ya Cao,4

Association between time of discharge from ICU and hospital mortality: a systematic review and meta-analysis

Background Epidemiological studies have provided inconsistent results on whether intensive care unit (ICU) discharge at night and on weekends is associated with an increased risk of mortality. This systematic review and meta-analysis aimed to determine whether ICU discharge time was associated with hospital mortality. Methods The PubMed, Embase, and Scopus databases were searched...

Patient-specific core decompression surgery for early-stage ischemic necrosis of the femoral head

Introduction Core decompression is an efficient treatment for early stage ischemic necrosis of the femoral head. In conventional procedures, the pre-operative X-ray only shows one plane of the ischemic area, which often results in inaccurate drilling. This paper introduces a new method that uses computer-assisted technology and rapid prototyping to enhance drilling accuracy...

The theoretical analysis and numerical simulation of the metal jet incoherence

By the analysis of the classic jet theory and literature, the regions of no-jet, convergent jet and incoherent jet are given in convergent point coordinate system. The theoretical analysis of metal jet incoherence formation explains Walker's jet incoherence theory which is based on experiment, and it's proved that in the supersonic portion of the metal jet, both the incoherence...

Retrospection-Simulation-Revision: Approach to the Analysis of the Composition and Characteristics of Medical Waste at a Disaster Relief Site

A large amount of medical waste is produced during disaster relief, posing a potential hazard to the habitat and the environment. A comprehensive understanding of the composition and characteristics of medical waste that requires management is one of the most basic steps in the development of a plan for medical waste management. Unfortunately, limited reliable information is...

Fluid–Structure Interaction-Based Biomechanical Perception Model for Tactile Sensing

The reproduced tactile sensation of haptic interfaces usually selectively reproduces a certain object attribute, such as the object's material reflected by vibration and its surface shape by a pneumatic nozzle array. Tactile biomechanics investigates the relation between responses to an external load stimulus and tactile perception and guides the design of haptic interface...

PCP-ML: Protein characterization package for machine learning

Background Machine Learning (ML) has a number of demonstrated applications in protein prediction tasks such as protein structure prediction. To speed further development of machine learning based tools and their release to the community, we have developed a package which characterizes several aspects of a protein commonly used for protein prediction tasks with machine learning...

Tissue Distribution of trans-Resveratrol and Its Metabolites after Oral Administration in Human Eyes

experiment, analyzed the data, and prepared the manuscript. Zheng Wang, Shuo Yang, Tiemei Yin, Yaoli Zhang, and Yuanjun Qin assisted in conducting the experiment. Robert N. Weinreb assisted in the study design

Modeling and Computation of Transboundary Industrial Pollution with Emission Permits Trading by Stochastic Differential Game

Transboundary industrial pollution requires international actions to control its formation and effects. In this paper, we present a stochastic differential game to model the transboundary industrial pollution problems with emission permits trading. More generally, the process of emission permits price is assumed to be stochastic and to follow a geometric Brownian motion (GBM). We...

A soft stretchable bending sensor and data glove applications

Soft sensors are required to accommodate the flexible and deformable natures of the human body in wearable device applications. They are also suitable for integration with soft robotic devices to monitor the performance status and provide references for feedback control. However, the choices for bending sensors are still highly limited. In this paper, a soft bending sensor is...