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Search: authors:"Zhenwang Jie"

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Large-scale ex vivo generation of human neutrophils from cord blood CD34+ cells

Conventional high-dose chemotherapy frequently leads to severe neutropenia, during which patients experience a high risk of infection. Although support care with donor’s neutrophils is possible this choice is largely hampered by the limited availability of matched donors. To overcome this problem, we explored a large-scale ex vivo production of neutrophils from hematopoietic stem...