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Surgical Downstaging in an Open-Label Phase II Trial of Denosumab in Patients with Giant Cell Tumor of Bone

Background Surgical resection with curative intent for giant cell tumor of bone (GCTB) may be associated with severe morbidity. This interim analysis evaluated reduction in surgical invasiveness after denosumab treatment in patients with resectable GCTB. Methods Patients with primary or recurrent GCTB, for whom the initially planned surgery was associated with functional...

Identification des indicateurs de dégradation de la forêt de tapia (Uapaca bojeri) par une analyse sylvicole

Identification of Degradation Indicators of Tapia Forest (Uapaca bojeri) by Sylvicultural Analysis. Une étude des effets de lisière sur les sex-ratios de six espèces de rongeurs a été abordée dans la Réserve de Masako à 15 km de Kisangani en RDC. Une collection de 1789 individus capturés durant deux ans a permis d'analyser les sex-ratios dans la jachère, la forêt secondaire et la...

Analysis of the presence of cutaneous and mucosal papillomavirus types in ductal lavage fluid, milk and colostrum to evaluate its role in breast carcinogenesis