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Molecular characterization of the malaria vector Anopheles barbirostris van der Wulp in Sri Lanka

Background Anopheles barbirostris is a vector of malaria in Sri Lanka. The taxon exists as a species complex in the Southeast Asian region. Previous studies using molecular markers suggest that there are more than 4 distinct clades within the An. barbirostris complex in Southeast Asia. The present study characterizes Sri Lankan An. barbirostris using mtDNA cytochrome oxidase ...

Detection of 1014F kdr mutation in four major Anopheline malaria vectors in Indonesia

Din Syafruddin 0 Anggi PN Hidayati 0 Puji BS Asih 0 William A Hawley Supratman Sukowati Neil F Lobo 0 Eijkman Institute for Molecular Biology , Jalan Diponegoro, 69, Jakarta 10430 , Indonesia

Progress towards malaria elimination in Sabang Municipality, Aceh, Indonesia

Background Indonesia has set 2030 as its deadline for elimination of malaria transmission in the archipelago, with regional deadlines established according to present levels of malaria endemicity and strength of health infrastructure. The Municipality of Sabang which historically had one of the highest levels of malaria in Aceh province aims to achieve elimination by the end of ...

Existence of the rdl mutant alleles among the anopheles malaria vector in Indonesia

Background The gamma-aminobutyric acid (GABA) receptor-chloride channel complex is known to be the target site of dieldrin, a cyclodiene insecticide. GABA-receptors, with a naturally occurring amino acid substitution, A302S/G in the putative ion-channel lining region, confer resistance to cyclodiene insecticides that includes aldrin, chlordane, dieldrin, heptachlor, endrin and ...

The baseline distribution of malaria in the initial phase of elimination in Sabang Municipality, Aceh Province, Indonesia

Background Sabang Municipality, in Aceh Province, Indonesia, plans to initiate a malaria elimination programme in 2013. A baseline survey of the distribution of malaria in the municipality was conducted to lay the foundations for an evidence-based programme and to assess the island’s readiness to begin the elimination process. Methods The entire population of the municipality was ...

Malaria prevalence in Nias District, North Sumatra Province, Indonesia

Background The Nias district of the North Sumatra Province of Indonesia has long been known to be endemic for malaria. Following the economic crisis at the end of 1998 and the subsequent tsunami and earthquake, in December 2004 and March 2005, respectively, the malaria control programme in the area deteriorated. The present study aims to provide baseline data for the establishment ...