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118 SNPs of folate-related genes and risks of spina bifida and conotruncal heart defects

Background Folic acid taken in early pregnancy reduces risks for delivering offspring with several congenital anomalies. The mechanism by which folic acid reduces risk is unknown. Investigations into genetic variation that influences transport and metabolism of folate will help fill this data gap. We focused on 118 SNPs involved in folate transport and metabolism. Methods Using ...

18-tägige Schmerzen waren Zoster-Vorboten

einseitigen en (dermatomalen) Schmerzen nach drei Tam kag gen noch keine vesikulären Hautveränder e ,zB rungen zu beobachten seien. l .cSuh BS ■ H © Für die Gesundheit ist es durchaus riskant, Frau zu sein. Als

A Model for Interprofessional Health Disparities Education: Student-Led Curriculum on Chronic Hepatitis B Infection

BACKGROUND Although health disparities are commonly addressed in preclinical didactic curricula, direct patient care activities with affected communities are more limited. PURPOSE To address this problem, health professional students designed a preclinical service-learning curriculum on hepatitis B viral (HBV) infection, a major health disparity affecting the Asian/Pacific Islander ...

A Retrospective Comparison of Bovine Pericardium and Polytetrafluoroethylene Patch for Closure of Ventricular Septal Defects

This retrospective study compared the immediate post-operative (first month) and mid-term (up to 5 years post-operation) results of 22 patients with isolated ventricular septal defects who underwent surgical correction with bovine pericardium with 57 similar patients who received a polytetrafluoroethylene (PTFE) patch. There were no cases of early (in the first month) mortality in ...

A Systematic Review of Approaches for Engaging Patients for Research on Rare Diseases

BACKGROUND Patients with rare diseases have limited access to useful information to guide treatment decisions. Engagement of patients and other stakeholders in clinical research may help to ensure that research efforts in rare diseases address relevant clinical questions and patient-centered health outcomes. Rare disease organizations may provide an effective means to facilitate ...

A biosegmentation benchmark for evaluation of bioimage analysis methods

Background We present a biosegmentation benchmark that includes infrastructure, datasets with associated ground truth, and validation methods for biological image analysis. The primary motivation for creating this resource comes from the fact that it is very difficult, if not impossible, for an end-user to choose from a wide range of segmentation methods available in the literature ...

A closed-circuit anesthesia ventilator facilitates significant reduction in sevoflurane consumption in clinical practice

Rashiq 0 BS . Ban C. H. Tsui 0 0 T. O ̈ zelsel, MD (&) S. H. Kim, RPh S. Rashiq, BM BS B. C. H. Tsui, MD Department of Anesthesiology and Pain Medicine, University of Alberta , Edmonton, AB , Canada - To

A novel intra-operative, high-resolution atrial mapping approach

Purpose A new technique is demonstrated for extensive high-resolution intra-operative atrial mapping that will facilitate the localization of atrial fibrillation (AF) sources and identification of the substrate perpetuating AF. Methods Prior to the start of extra-corporal circulation, a 8 × 24-electrode array (2-mm inter-electrode distance) is placed subsequently on all the right ...

A randomized, double-blind, placebo-controlled study assessing the safety and tolerability of regadenoson in subjects with asthma or chronic obstructive pulmonary disease

Bruce M. Prenner Stan Bukofzer MBBCh MMed (Int) Sarah Behm BS Kathleen Feaheny MS Bruce E. McNutt MD Background. Adenosine receptor stress agents for myocardial perfusion imaging (MPI) may cause

Accuracy of Race, Ethnicity, and Language Preference in an Electronic Health Record

BACKGROUND Collection of data on race, ethnicity, and language preference is required as part of the “meaningful use” of electronic health records (EHRs). These data serve as a foundation for interventions to reduce health disparities. OBJECTIVE Our aim was to compare the accuracy of EHR-recorded data on race, ethnicity, and language preference to that reported directly by ...

Adipose-derived Mesenchymal Stem Cells Are Phenotypically Superior for Regeneration in the Setting of Osteonecrosis of the Femoral Head

able to evaluate the efficacy of these cellular therapies side-by-side in patients with bilateral early-stage disease. Acknowledgments We thank Lois A. Rowe BS (Mayo Clinic Center for Regenerative

Adipositas schmälert Impfschutz

Übergewicht durch eine Stimulation mit den In¥uenzaimpfstämmen in geringerem Maß aktiviert werden. ■ bs

Agriculture and the promotion of insect pests: rice cultivation in river floodplains and malaria vectors in The Gambia

Background Anthropogenic modification of natural habitats can create conditions in which pest species associated with humans can thrive. In order to mitigate for these changes, it is necessary to determine which aspects of human management are associated with the promotion of those pests. Anopheles gambiae, the main Africa malaria vector, often breeds in rice fields. Here the ...

Akuter Husten hat oft eine chronische Ursache

% der über 40-Jährigen betroffen sind. bs ■ Große regionale Unterschiede Daraus ergibt sich ein sehr heterogenes Bild. So schneiden zwar Länder wie Frankreich, Slowenien und Deutschland, gemessen an den

Akuter Husten ist oft nicht harmlos!

Atemwegsobstruktion wurden, je nach Bewertungsmaßstab, bei bis zu 10% der Patienten entdeckt. (bs)

Alkalisch oder sauer duschen?

Nasensekret enthaltene Lysozym, das der Abwehr von Bakterien dient, in alkalischem Milieu inaktiviert wird. Dies gelte es bei nicht allergisch bedingten Rhinosinusitiden zu bedenken. (bs) Chusakul S et al