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Key Knowledge Gaps for Plasmodium vivax Control and Elimination

There is inadequate understanding of the biology, pathology, transmission, and control of Plasmodium vivax, the geographically most widespread cause of human malaria. During the last decades, study of this species was neglected, in part due to the erroneous belief that it is intrinsically benign. In addition, many technical challenges in culturing the parasite also hampered ...

Traffic-related air pollution and spectacles use in schoolchildren

, China, 9 IMIM-Parc Salut Mar , Spain - OPEN ACCESS Funding: The research leading to these results has received funding from the European Research Council under the ERC Grant Agreement number 268479 ... and the BREATHE project was approved (No. 2010/41221/I) by the Clinical Research Ethical Committee of the Parc de Salut MAR, Barcelona, Spain. Outcome and covariate data We considered the use of

A guide to performing a peer review of randomised controlled trials

that only emerges after a detailed read or © 2015 Del Mar and Hoffmann. Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http

Malaria incidence in Myanmar 2005–2014: steady but fragile progress towards elimination

Myat Phone Kyaw 4 Chit Soe 3 Mar Mar Kyi 6 Josh Hanson 5 6 7 0 Myanmar Medical Association , Yangon , Myanmar 1 Department of Medical Care, Ministry of Health , Nay Pyi Taw , Myanmar 2 Department of

Educational interventions to improve people’s understanding of key concepts in assessing the effects of health interventions: a systematic review protocol

study . Integr Cancer Ther . 2007 ; 6 : 345 - 53 . doi: 10 .1177/1534735407309482. 17. Hoffmann TC , Del Mar C. Patients' expectations of the benefits and harms of treatments, screening, and tests . JAMA

Parents’ beliefs and knowledge about the management of acute otitis media: a qualitative study

provided by the Australian Government Department of Health. Tammy C Hoffmann and Chris Del Mar are chief investigators at the Centre for Research Excellence in Minimising Antibiotic Resistance from Acute ... Respiratory Infections (NHMRC grant 1044904). 1. Venekamp RP , Sanders S , Glasziou PP , Del Mar CB , Rovers MM . Antibiotics for acute otitis media in children . Cochrane Database Syst Rev . 2013 ; 1

The Safety of a Conservative Fluid Replacement Strategy in Adults Hospitalised with Malaria

Background A conservative approach to fluid resuscitation improves survival in children with severe malaria; however, this strategy has not been formally evaluated in adults with the disease. Methods Adults hospitalised with malaria at two tertiary referral hospitals in Myanmar received intravenous fluid replacement with isotonic saline, administered at a maintenance rate using a ...

Comparison of the glidescope®, flexible fibreoptic intubating bronchoscope, iPhone modified bronchoscope, and the Macintosh laryngoscope in normal and difficult airways: a manikin study

manikin study Adrian Langley 0 Gabriel Mar Fan 0 0 Equal contributors Department of Anaesthesia and Pain Management, QE II Jubilee Hospital , Metro South HHN, Coopers Plain, QLD 4108 , Australia

The impact of health literacy and life style risk factors on health-related quality of life of Australian patients

Australia; Professor Grant Russell (Chief investigator) Monash University Australia; Professor Chris Del Mar (Associate Investigator) Bond University Australia; Dr Jane Lloyd (Associate Investigator ... . Optimal health literacy measurement for the clinical setting: a systematic review . Patient Educ Couns . 2015 ; 98 : 1295 - 307 . 42. Joshi C , Jayasinghe UW , Parker S , Del Mar C , Russell G , Lloyd J

General Practitioner Antimicrobial Stewardship Programme Study (GAPS): protocol for a cluster randomised controlled trial

. 2011 ; 52 Suppl 5 : S397 - 428 . 11. Mc Kenzie D , Rawlins MD , Del Mar C. Antimicrobial stewardship: what's it all about? Aust Prescr . 2013 ; 36 : 116 - 20 . 12. Antibiotic resistance: a problem for ... rates for acute respiratory-tract infections: a multinational, cluster, randomised, factorial, controlled trial . Lancet . 2013 ; 382 ( 9899 ): 1175 - 82 . 20. Spurling GK , Del Mar CB , Dooley L , Foxlee

Variability of Gene Expression Identifies Transcriptional Regulators of Early Human Embryonic Development

; 15 ( 10 ): 1388 - 92 . doi: 10.1101/gr.3820805 PMID: 16204192; PubMed Central PMCID: PMC1240081. 4. Mar JC , Rubio R , Quackenbush J. Inferring steady state single-cell gene expression distributions ... the United States of America . 1997 ; 94 ( 3 ): 814 - 9 . PMID: 9023339 ; PubMed Central PMCID : PMC19596 . 13. Mar JC , Matigian NA , Mackay-Sim A , Mellick GD , Sue CM , Silburn PA , et al. Variance

What is the effect of a formalised trauma tertiary survey procedure on missed injury rates in multi-trauma patients? Study protocol for a randomised controlled trial

; 39 : 107 - 14 . 2. Keijzers GB , Giannakopolous GF , Del Mar C , Bakker FC , Geeraedts Jr LM . The effect of tertiary surveys on missed injuries in trauma: a systematic review . Scand J Trauma Resusc

The prognostic utility of bedside assessment of adults hospitalized with malaria in Myanmar: a retrospective analysis

Background Data collected in clinical trials have been used to develop scoring systems that identify adults with malaria at greatest risk of death. One of these, the RCAM score, can be simply determined by measuring a patient’s Glasgow Coma Score and respiratory rate on admission to hospital. However the safety of using the RCAM score to define high-risk patients has not been ...

Application of Gene Expression Trajectories Initiated from ErbB Receptor Activation Highlights the Dynamics of Divergent Promoter Usage

Jessica C. Mar 0 1 Ramani Ramchandran, Medical College of Wisconsin, UNITED STATES 0 1 Department of Systems and Computational Biology, Albert Einstein College of Medicine , Bronx, NY , United States of ... : 545 . doi: 10 .1186/ 1471 -2164-10-545 PMID: 19925682; PubMed Central PMCID : PMC2785842 . 11. Mar JC , Quackenbush J . Decomposition of gene expression state space trajectories . PLoS Comput Biol

New investments in primary care in Australia

There is a crisis in primary care health workforce shortages in Australia. Its government has attempted to fix this by role-substitution (replacing medical work with nursing instead). This was not completely successful. Obstacles included entrenched social roles (leading to doctors 'checking' their nurse role-substituted work) and structures (nurses subservient to doctors) - both ...

Urinary tract infections in healthy women: a revolution in management?

Chris Del Mar 0 0 School of Medicine, Faculty of Health Sciences, Bond University , Queensland 4229 , Australia Background: Urinary infection in otherwise healthy women has largely been a

The Imperative to Share Clinical Study Reports: Recommendations from the Tamiflu Experience

/WarningLettersandNoticeofVio lationLetterstoPharmaceuticalCompanies/UCM 166329.pdf. Accessed 6 March 2012 . 11. Jefferson T , Jones MA , Doshi P , Del Mar CB , Heneghan CJ , et al. ( 2012 ) Neuraminidase inhibitors for

Do you think it's a disease? a survey of medical students

Background The management of medical conditions is influenced by whether clinicians regard them as "disease" or "not a disease". The aim of the survey was to determine how medical students classify a range of conditions they might encounter in their professional lives and whether a different name for a condition would influence their decision in the categorisation of the condition ...

Global Transcriptome Analysis of Lactococcus garvieae Strains in Response to Temperature

Lactococcus garvieae is an important fish and an opportunistic human pathogen. The genomic sequences of several L. garvieae strains have been recently published, opening the possibility of global studies on the biology of this pathogen. In this study, a whole genome DNA microarray of two strains of L. garvieae was designed and validated. This DNA microarray was used to investigate ...

Patients’ expectations of acute low back pain management: implications for evidence uptake

Background In many countries, general practitioner (GP) care of acute low back pain often does not adhere to evidence-based clinical guidelines. There has been little exploration of this deviation from evidence-based care from the patients’ perspective, particularly in relation to patients’ care expectations. The aim of this study was to explore the care expectations in patients ...