Advanced search    

Search: authors:"mar"

596 papers found.
Use AND, OR, NOT, +word, -word, "long phrase", (parentheses) to fine-tune your search.

Identification and validation of uterine stimulant methylergometrine as a potential inhibitor of caspase-1 activation

Inflammasomes are intracellular multiprotein complexes of the innate immune system. Upon an inflammatory insult, such as infection or intracellular damage, a nucleotide-binding oligomerization domain-like receptor (NLR) sensor protein and the adaptor protein ASC (apoptosis-associated speck-like protein containing a caspase activation and recruitment domain) are assembled to ...

Team Creative Environment as a Mediator Between CWX and R&D Team Performance and Moderating Boundary Conditions

Purpose The purpose of this study was to investigate how high-quality dyadic co-worker relationships (CWXs) favour or hinder team performance. Specifically, we examine the role played by CWX, team creative environment, job complexity and task interdependence to achieve higher levels of team performance. Design/Methodology/Approach We analyse data from 410 individuals belonging to ...

BMP type II receptor as a therapeutic target in pulmonary arterial hypertension

Pulmonary arterial hypertension (PAH) is a chronic disease characterized by a progressive elevation in mean pulmonary arterial pressure. This occurs due to abnormal remodeling of small peripheral lung vasculature resulting in progressive occlusion of the artery lumen that eventually causes right heart failure and death. The most common cause of PAH is inactivating mutations in the ...

MAM-E17 rat model impairments on a novel continuous performance task: effects of potential cognitive enhancing drugs

cm) modified to include a touch-sensitive monitor (Elo Touch Solutions, Inc., Milpitas, CA, USA; see Mar et al. 2013; Oomen et al. 2013) controlled through in-house software (Visual Basic 2010 ... antinociceptive agent acting vianeuronal nicotinic acetylcholine receptors: II. In vivo characterization . J Pharmacol Exp Ther 285 : 787 - 794 . doi: 10 .1002/(ISSN) 2052 - 1707 Bari A , Eagle DM , Mar AC et al

Environmental factors influencing the spatio-temporal distribution of Carybdea marsupialis (Lineo, 1978, Cubozoa) in South-Western Mediterranean coasts

ValparaÂõso, ValparaÂõso, Chile, 2 Marine Biology and Oceanography Department, Institut de Ciències del Mar, Consejo Superior de Investigaciones CientÂõficas , Barcelona , Spain , 3 Dipartimento di Scienze ... ( 15 mm) individuals. The Spanish Ministry of the Environment (DireccioÂn General de Sostenibilidad de la Costa y el Mar) and the regional environmental authority (DireccioÂn General del Agua) supported

Ethnicity and the first diagnosis of a wide range of cardiovascular diseases: Associations in a linked electronic health record cohort of 1 million patients

Background While the association of ethnic group with individual cardiovascular diseases has been studied, little is known about ethnic differences in the initial lifetime presentation of clinical cardiovascular disease in contemporary populations. Methods and results We studied 1,068,318 people, aged ≥30 years and free from diagnosed CVD at baseline (90.9% White, 3.6% South Asian ...

PREditOR: a synthetic biology approach to removing heterochromatin from cells

It is widely accepted that heterochromatin is necessary to maintain genomic stability. However, direct experimental evidence supporting this is slim. Previous studies using either enzyme inhibitors, gene knockout or knockdown studies all are subject to the caveat that drugs may have off-target effects and enzymes that modify chromatin proteins to support heterochromatin formation ...

PREditOR: a synthetic biology approach to removing heterochromatin from cells

It is widely accepted that heterochromatin is necessary to maintain genomic stability. However, direct experimental evidence supporting this is slim. Previous studies using either enzyme inhibitors, gene knockout or knockdown studies all are subject to the caveat that drugs may have off-target effects and enzymes that modify chromatin proteins to support heterochromatin formation ...

Leveraging workflow control patterns in the domain of clinical practice guidelines

Background Clinical practice guidelines (CPGs) include recommendations describing appropriate care for the management of patients with a specific clinical condition. A number of representation languages have been developed to support executable CPGs, with associated authoring/editing tools. Even with tool assistance, authoring of CPG models is a labor-intensive task. We aim at ...

Traffic-related air pollution and spectacles use in schoolchildren

, China, 9 IMIM-Parc Salut Mar , Spain - OPEN ACCESS Funding: The research leading to these results has received funding from the European Research Council under the ERC Grant Agreement number 268479 ... and the BREATHE project was approved (No. 2010/41221/I) by the Clinical Research Ethical Committee of the Parc de Salut MAR, Barcelona, Spain. Outcome and covariate data We considered the use of

Body image satisfaction and weight concerns among a Mediterranean adult population

Background People tend to underestimate their current weight and overestimate their height minimizing health risk factors. The aim of this study was to assess body weight satisfaction, acceptance of body image, weight concern and dieting habits among a Mediterranean adult population. Methods Cross-sectional survey was carried out (2009–2010) in the Balearic Islands, Spain. A random ...

Key Knowledge Gaps for Plasmodium vivax Control and Elimination

There is inadequate understanding of the biology, pathology, transmission, and control of Plasmodium vivax, the geographically most widespread cause of human malaria. During the last decades, study of this species was neglected, in part due to the erroneous belief that it is intrinsically benign. In addition, many technical challenges in culturing the parasite also hampered ...

Executive Functioning in Men with Schizophrenia and Substance Use Disorders. Influence of Lifetime Suicide Attempts

Background Lifetime suicide attempts in patients with comorbidity between psychotic disorders and Substance Use Disorder (SUD), known as dual diagnosis, was associated with a worse clinical and cognitive state, poor prognosis and premature death. However, to date no previous study has examined the cognitive performance of these patients considering as independent the presence or ...

Correlates of sex trading among male non-injecting drug users in Myanmar: a cross-sectional study

Background Sex trading is a recognized risk factor for human immune deficiency virus infection and other sexually transmitted infections among non-injecting drug users (NIDUs). However, very little research has addressed the factors associated with sex trading among male NIDUs in Myanmar. Methods A cross-sectional study was conducted from January to February 2010 using the ...

Aspergillus sydowii and Other Potential Fungal Pathogens in Gorgonian Octocorals of the Ecuadorian Pacific

(Corallium rubrum L.) . Mar Biol . 2006 ; 149 : 1059 ± 1070 . doi: 10 .1007/s00227-006- 0302-8 6. Gates RD , Ainsworth TD . The nature and taxonomic composition of coral symbiomes as drivers of performance ... limits in scleractinian corals . J Exp Mar Bio Ecol . Elsevier B.V. ; 2011 ; 408 : 94 ± 101 . doi: 10 . 1016/j.jembe. 2011 . 07 .029 7. NystroÈm M , Folke C , Moberg F. Coral reef disturbance and

Preventing the Complications Associated with the Use of Dermal Fillers in Facial Aesthetic Procedures: An Expert Group Consensus Report

Background The use of dermal fillers in minimally invasive facial aesthetic procedures has become increasingly popular of late, yet as the indications and the number of procedures performed increase, the number of complications is also likely to increase. Paying special attention to specific patient characteristics and to the technique used can do much to avoid these complications. ...

Optical system for measuring the spectral retardance function in an extended range

Background Optical retarders are key elements for the control of the state of polarization of light, and their wavelength dependance is of great importance in a number of applications. Methods We apply a well-known technique for determinig the spectral retardance by measuring the transmission spectra between crossed or parallel polarizers. But we we develop an optical system to ...

Differences in gut microbiota profile between women with active lifestyle and sedentary women

Physical exercise is a tool to prevent and treat some of the chronic diseases affecting the world’s population. A mechanism through which exercise could exert beneficial effects in the body is by provoking alterations to the gut microbiota, an environmental factor that in recent years has been associated with numerous chronic diseases. Here we show that physical exercise performed ...

Dietary patterns are associated with lung function among Spanish smokers without respiratory disease

Background Diet can help preserve lung function in smokers, in addition to avoidance of smoking. The study aimed to evaluate associations between dietary patterns and lung function in smokers without respiratory disease. Methods This cross-sectional study analysed baseline data from randomised representative smokers without respiratory disease (n = 207, aged 35–70 years), selected ...