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Does the rising placebo response impact antihypertensive clinical trial outcomes? An analysis of data from the Food and Drug Administration 1990-2016

. Author Contributions Conceptualization: Arif Khan, Kaysee Fahl Mar, Walter A. Brown. Data curation: Kaysee Fahl Mar. 15 / 17 Formal analysis: Kaysee Fahl Mar. Investigation: Kaysee Fahl Mar ... . Methodology: Arif Khan, Kaysee Fahl Mar, Walter A. Brown. Project administration: Arif Khan. Supervision: Arif Khan, Joshua Schilling, Walter A. Brown. Validation: Arif Khan, Kaysee Fahl Mar, Joshua

Decreased suicide rates in recent antidepressant clinical trials

. Kaysee Fahl Mar, MA, Sagarika Gokul, MBBS, and Dr. Brown report neither financial interest nor potential conflicts of interest. Open Access This article is distributed under the terms of the Creative C o

Best practices in road transport: An exploratory study

Journal of Industrial Engineering and Management JIEM 2013-0953 Best Practices in Road Transport: An Exploratory Study Mar Fernández Vázquez-Noguerol 0 Iván González-Boubeta 0 Pablo Dominguez

Economic and environmental packaging sustainability: A case study

Journal of Industrial Engineering and Management JIEM 2013-0953 Economic and Environmental Packaging Sustainability: A Case Study Iván González-Boubeta Mar Fernández-Vázquez-Noguerol Pablo

Zinc-finger domains in metazoans: evolution gone wild

, Spain 1 Evolutionary Genomics Group, Research Programme in Biomedical Informatics, Hospital del Mar Research Institute (IMIM)-Universitat Pompeu Fabra (UPF) , Barcelona , Spain A new study uncovers a

Polyphenol estimated intake and dietary sources among older adults from Mallorca Island

polyphenol absorption by the body. Supporting information S1 Table. Food contributors table. (PDF) Author Contributions Conceptualization: Maria del Mar Bibiloni, Josep A. Tur. Data curation: Joanne Karam ... , Maria del Mar Bibiloni. Formal analysis: Joanne Karam, Maria del Mar Bibiloni. Funding acquisition: Josep A. Tur. Investigation: Joanne Karam, Maria del Mar Bibiloni. Project administration: Josep A

The clinical characteristics of adults with rheumatic heart disease in Yangon, Myanmar: An observational study

that surgery is out of the reach of almost every Myanmar citizen (personal communication, Professor Mar Mar Kyi). Although PBMV is less expensive (out-of-pocket expenses: USD1000) a benefit from this ... . Formal analysis: Josh Hanson. Investigation: Nan Phyu Sin Toe Myint, Ne Myo Aung, Myint Soe Win, Thu Ya Htut, Mar Mar Kyi. Methodology: Josh Hanson. Supervision: Ne Myo Aung, Myint Soe Win, David A

Bio-Prospecting in the Arctic: An Overview of the Interaction Between the Rights of Indigenous Peoples and Access and Benefit Sharing

INDIGENOUS PEOPLES AND ACCESS AND BENEFIT SHARING MAR CAMPINS ERITJA* INTRODUCTION Apart from its own particular climate conditions, the Arctic region is characterized by its seasonally ice-covered ocean.1

Influence of pyrolysis temperature and production unit on formation of selected PAHs, oxy-PAHs, N-PACs, PCDDs, and PCDFs in biochar—a screening study

The influence of reactor type and operating conditions of the pyrolysis unit on the final concentration of toxic contaminants in biochar remains unclear. Therefore, we determined the concentrations of polycyclic aromatic hydrocarbons (PAHs), oxygenated polycyclic aromatic hydrocarbons (oxy-PAHs), nitrogen-containing polycyclic aromatic compounds (N-PACs), polychlorinated dibenzo...

Identifying unmet clinical need in hypertrophic cardiomyopathy using national electronic health records

. Supplemental methods. (DOC) Author Contributions Conceptualization: Mar Pujades-Rodriguez, Oliver P. Guttmann, Perry Elliott, Harry Hemingway. Data curation: Mar Pujades-Rodriguez, Arturo Gonzalez-Izquierdo ... , Bram Duyx. Formal analysis: Mar Pujades-Rodriguez. Funding acquisition: Harry Hemingway. Methodology: Mar Pujades-Rodriguez, Oliver P. Guttmann. Project administration: Mar Pujades-Rodriguez

Team Creative Environment as a Mediator Between CWX and R&D Team Performance and Moderating Boundary Conditions

Purpose The purpose of this study was to investigate how high-quality dyadic co-worker relationships (CWXs) favour or hinder team performance. Specifically, we examine the role played by CWX, team creative environment, job complexity and task interdependence to achieve higher levels of team performance. Design/Methodology/Approach We analyse data from 410 individuals belonging to...

Identification and validation of uterine stimulant methylergometrine as a potential inhibitor of caspase-1 activation

Inflammasomes are intracellular multiprotein complexes of the innate immune system. Upon an inflammatory insult, such as infection or intracellular damage, a nucleotide-binding oligomerization domain-like receptor (NLR) sensor protein and the adaptor protein ASC (apoptosis-associated speck-like protein containing a caspase activation and recruitment domain) are assembled to...

Understanding the mechanism of the decomposition reaction of nitroethyl benzoate through the Molecular Electron Density Theory

University of Technology , Warszawska 24, 31-155 Cracow , Poland 2 Mar Ríos-Gutiérrez The molecular mechanism of the decomposition reaction of nitroethyl benzoate (NEB) 1 yielding nitroethylene 2 and

Decisional balance and processes of change in community-recruited with moderate-high versus mild severity of cannabis dependence

Albein-Urios. Formal analysis: Mã del Mar Rueda. The data collection and the field work were performed by the FQM356 research group as part Investigation: Francisca LoÂpez-Torrecillas, Eva MarÂõa LoÂpez

A transcription network of interlocking positive feedback loops maintains intracellular iron balance in archaea

Iron is required for key metabolic processes but is toxic in excess. This circumstance forces organisms across the tree of life to tightly regulate iron homeostasis. In hypersaline lakes dominated by archaeal species, iron levels are extremely low and subject to environmental change; however, mechanisms regulating iron homeostasis in archaea remain unclear. In previous work, we...

An optimization design proposal of automated guided vehicles for mixed type transportation in hospital environments

Aim The aim of this paper is to present an optimization proposal in the automated guided vehicles design used in hospital logistics, as well as to analyze the impact of its implementation in a real environment. Method This proposal is based on the design of those elements that would allow the vehicles to deliver an extra cart by the towing method. So, the proposal intention is to...