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Identification and validation of uterine stimulant methylergometrine as a potential inhibitor of caspase-1 activation

Inflammasomes are intracellular multiprotein complexes of the innate immune system. Upon an inflammatory insult, such as infection or intracellular damage, a nucleotide-binding oligomerization domain-like receptor (NLR) sensor protein and the adaptor protein ASC (apoptosis-associated speck-like protein containing a caspase activation and recruitment domain) are assembled to ...

Weight Management in Patients with Type 1 Diabetes and Obesity

surgeries are valid methods for weight management in patients with T1D. Compliance with Ethical Standards Conflict of Interest Adham Mottalib, Megan Kasetty, Jessica Y. Mar, Taha Elseaidy, and Sahar

Team Creative Environment as a Mediator Between CWX and R&D Team Performance and Moderating Boundary Conditions

Purpose The purpose of this study was to investigate how high-quality dyadic co-worker relationships (CWXs) favour or hinder team performance. Specifically, we examine the role played by CWX, team creative environment, job complexity and task interdependence to achieve higher levels of team performance. Design/Methodology/Approach We analyse data from 410 individuals belonging to ...

Preventing the Complications Associated with the Use of Dermal Fillers in Facial Aesthetic Procedures: An Expert Group Consensus Report

Background The use of dermal fillers in minimally invasive facial aesthetic procedures has become increasingly popular of late, yet as the indications and the number of procedures performed increase, the number of complications is also likely to increase. Paying special attention to specific patient characteristics and to the technique used can do much to avoid these complications. ...

Breast cancer risk after diagnosis by screening mammography of nonproliferative or proliferative benign breast disease: a study from a population-based screening program

-Rocamora M. Roman M. Sala Department of Epidemiology and Evaluation, IMIM (Hospital del Mar Medical Research Institute) , Pg. Mar tim 25-29, 08003 Barcelona, Catalonia , Spain 2 Mar a Sala on behalf of the

Rationale and Design of a Randomized, Double-Blind, Placebo Controlled Multicenter Trial to Study Efficacy, Security, and Long Term Effects of Intermittent Repeated Levosimendan Administration in Patients with Advanced Heart Failure: LAICA study

Research Unit , Fundacin Rafael Clavijo para la Investigacin Biomdica, Hospital Universitario de Canarias , La Laguna, Sta. Cruz de Tenerife, Spain 4 M. del Mar Garca-Saiz Department of Clinical Pharmacology ... Department of Cardiology, Hospital Virgen de la Nieves , Granada, Spain 9 M del Mar Garca-Saiz. Department of Clinical Pharmacol- ogy Hospital Universitario de Canarias. La Laguna. Sta. Cruz de Tenerife

Treatment of bone tumours by radiofrequency thermal ablation

Granada, Spain 1 F. R. Santiago M. del Mar Castellano Garca J. L. M. Montes M. R. Garca J. M. T. Fernandez Traumatology Hospital (Ciudad Sanitaria Virgen de las Nieves) , Carretera de Jaen SN, 18013 Granada

Encoding processes and the recall of text

Two experiments investigated the proposition that the amount of cognitive effort expended to encode information will be directly related to recall of that information. While previous research has shown that amount of processing may affect recall, these studies have generally drawn on the notion of an elaborated memory representation to explain their results. In this study, the ...

The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data

& Dara S. Manoach & Jean-Luc Martinot & Mar Matarin & Karen A. Mather & Manuel Mattheisen & Morten Mattingsdal & Andreas Meyer-Lindenberg & Colm McDonald & Andrew M. McIntosh & Francis J. McMahon & Katie L