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Src64B phosphorylates Dumbfounded and regulates slit diaphragm dynamics: Drosophila as a model to study nephropathies

Drosophila nephrocytes are functionally homologous to vertebrate kidney podocytes. Both share the presence of slit diaphragms that function as molecular filters during the process of blood and haemolymph ultrafiltration. The protein components of the slit diaphragm are likewise conserved between flies and humans, but the mechanisms that regulate slit diaphragm dynamics in...

Mind bomb 2, a founder myoblast-specific protein, regulates myoblast fusion and muscle stability

Marta Carrasco-Rando 0 Mar Ruiz-Gmez 0 0 Centro de Biologia Molecular Severo Ochoa, CSIC and UAM, Universidad Autonoma de Madrid , 28049, Madrid , Spain A fundamental step during Drosophila

SUMOylation modulates the function of Aurora-B kinase

the following proteins: -tubulin (Sigma), Aurora B (Abcam, BD Transduction), INCENP (Human GLPL serum, a gift from Manuel Valdivia, Hospital Puerta del Mar, Cadiz, Spain), Phospho-CENP-A (Ser7; Upstate

Real-time dynamics of the F-actin cytoskeleton during secretion from chromaffin cells

Daniel Giner Patricia eco Mara del Mar Francs Inmaculada Lpez Salvador Viniegra Luis M. Gutirrez ) - Transmitted light images showed an intricate and dynamic cytoplasmic structural network in