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Transversal incision of the vagina favors the remaining of the tape in the middle-third urethra compared to longitudinal incision during transobturator sling procedures for stress urinary incontinence

and Gynecology Timisoara County Hospital. The author presents interest and expertise in urogynecology, and has published many articles in the field of urogynecology. I. Sas–PhD, Senior Consultant and

Lowering the apoptotic threshold in colorectal cancer cells by targeting mitochondria

Background Colorectal cancer is the third most-common cancer and the second most-common cause of cancer related death in UK. Although chemotherapy plays significant role in the treatment of colorectal cancer, morbidity and mortality due to drug resistance and cancer metastasis are yet to be eliminated. Recently, doxycycline has been reported to have cytotoxic and anti...

Does Doxycycline work in synergy with cisplatin and oxaliplatin in colorectal cancer?

Background In recent years, apart from antibacterial properties, doxycycline is reported to have cytotoxic and anti-proliferative actions in various cancers including colorectal cancer. Colorectal cancer constitutes one of the most common cancers in the western population. Apart from surgery, chemotherapy plays crucial role in the treatment of colorectal cancer. Cisplatin and...