Nefrología (Madrid)

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List of Papers (Total 119)

Remisión molecular de una leucemia mieloide crónica en un paciente con segundo trasplante renal y hepatitis

Abstract Chronic myeloid leukemia (CML) is a myeloproliferative disorder characterized by clonal expansion of cells in the myeloid line, expressing the BCRABL fusion protein responsible for the oncogenic effect of CML. The current frontline therapy in CML is the BCR-ABL tyrosine kinase inhibitor, Imatinib. Although this drug has been shown to improve survival in CML patients, its...

Enfermedad celíaca y nefropatía membranosa

Celiac disease results from the interaction between gluten and immune, genetic, and environmental factors. Although the main clinical manifestations are derived from gastrointestinal system, it has been described some renal diseases, especially chronic glomerulonephritis. We describe a young female patient with celiac disease which appears after delivery. Moreover, she develops...

El factor de crecimiento de tejido conectivo (CTGF): factor clave en el inicio y la progresión del daño renal

Connective tissue growth factor (CTGF) is increased in several pathologies associated with fibrosis, including multiple renal diseases. CTGF is involved in biological processes such as cell cycle regulation, migration, adhesion and angiogenesis. Its expression is regulated by various factors involved in renal damage, such as Angiotensin II, transforming growth factor-beta, high...

Cirugía sin ingreso de pacientes con fístulas arteriovenosas para hemodiálisis: Actividad integrada en un servicio de cirugía general

Introduction: The increase of prevalent haemodialysis patients is a challenge for surgery units. Vascular access related complications are the main cause of hospital admissions in many dialysis units. Outpatient surgery could decrease waiting lists, cost and complications associated to vascular access. Material and methods: We have performed a prospective study of the vascular...

La ecografía carotídea es útil para predecir enfermedad coronaria y mortalidad en pacientes en hemodiálisis

Introduction: Cardiovascular disease and other complications of atherosclerosis are the most common cause of death in patients with chronic renal failure in maintenance hemodialysis (MHD). Carotid ultrasonography is a simple non-invasive tool to investigate the vascular system, by means of intima media thickness (IMT) measurement and carotid wall calcifications. Objective: To...

Evaluación económica de la hemodiálisis: Análisis de los componentes del coste basado en datos individuales

Background: Hemodialysis (HD) cost analysis provides information about the economic impact of the disease on the community. Its knowledge is crucial to adequate and optimize health resources. Our aim was to study sanitary and non-sanitary direct costs of HD, based on patients individual data. Furthermore, the effect of sociocultural factors and comorbidity on costs was evaluated...

Pauta de infusión manual automatizada: una forma práctica de prescribir la hemodiafiltración on-line posdilucional

Post-dilution on-line hemodiafiltration (OL-HDF) is the most efficient infusion mode to obtain maximum clearances of uremic toxins, with a recommended manual infusion flow (Qi) of 25% of the blood flow with the main limitation that causes alarms by hemoconcentration throughout the session. Recent technical advances allow automatic prescription of Qi if hematocrit and total...

Enfermedad renal ateroembólica: un análisis de los factores clínicos y terapéuticos que influyen en su evolución

Cholesterol embolism is a disease caused by distal showering of cholesterol crystal released from disintegration of arterial atheromatous plaques. It may occur spontaneously or more often after invasive vascular procedures or thrombolytic/anticoagulant agents. Forty five cases were diagnosed between 1989 and 2005 in three Spanish hospitals. The diagnosis was confirmed by...

Acute lupus hemophagocytic syndrome: report of a case

Hemophagocytic Syndrome is a clinical condition characterized by the activation of either macrophages or histiocytes with a prominent hemophagocytosis feature in the bone marrow and other reticuloendothelial systems. It leads to the phagocytosis of erythrocytes, leukocytes, platelets and their precursors. The presence of hemophagocytosis can be associated to infections...

¿Mejora la aproximación físico-química de Stewart-Fencl la valoración del equilibrio ácido-base en pacientes estables en hemodiafiltración?

Introduction: The traditional evaluation of acid-base status relies on the Henderson-Hasselbach equation. In 1983, an alternative approach, based on physical and chemical principles was proposed by P. Stewart. In this approach, plasma pH is determined by 3 independent variables: pCO2, Strong Ion Difference (SIDm), which is the difference between the strong cations (Na+, K+, Ca...

Implicaciones pronósticas de la enfermedad renal crónica en el anciano

Chronic kidney disease is considered to be a problem of public health problem from the application of Guidelines KDOQI/NKF. Majority patients diagnosed of chronic kidney disease are elderly. In these patients progression of renal disease is slow, being the mortality high to development of renal failure that needs dialysis. The current guidelines must apply with caution in these...

Dinámica de la secreción de PTH regulada por calcio en el hiperparatiroidismo secundario: comparación de la respuesta in vivo frente a in vitro

Aim: To compare the dynamics in vivo and in vitro calcium-PTH release of uremic patients with secondary hyperparathyroidism and their hyperplasic parathyroid glands after parathyroidectomy. Materials and methods: Seven patients with secondary HPT and their 23 hyperplasic glands obtained after surgical parathyroidectomy were evaluated. In vivo studies of the PTH secretion curve...

Causas de inicio no programado del tratamiento renal sustitutivo con hemodiálisis

Half of patients starting chronic hemodialysis used a transient vascular catheter as a vascular access (unplanned initiation). An objective of the Quality Management Group of the Spanish Society of Nephrology is to achieve that 80% of the patients starting hemodialysis do it with an arteriovenous fistula. We want to review the causes of non-planned hemodialysis nowadays. In 2010...