Journal of Cell Science

http://jcs.biologists.org

List of Papers (Total 15,649)

Correction: SIRT2 regulates NF-κB-dependent gene expression through deacetylation of p65 Lys310 (doi:10.1242/jcs.073783)

There was an error in J. Cell Sci. (2010) 123, [4251-4258][1] [(doi:10.1242/jcs.073783)][2]. The journal was informed that the p65 and myc (p65) blots in [Fig. 1][3]A,B are identical to those shown in fig. 3A,B of another paper by the same authors in BMC Genomics (2010) 11 , 22 ([doi:10.1186/

The Rho family GEF FARP2 is activated by aPKCι to control tight junction formation and polarity

The elaboration of polarity is central to organismal development and to the maintenance of functional epithelia. Among the controls determining polarity are the PAR proteins, PAR6, aPKCι and PAR3, regulating both known and unknown effectors. Here, we identify FARP2 as a ‘RIPR’ motif-dependent partner and substrate of aPKCι that is required for efficient polarisation and junction...

Correction: The PIKfyve complex regulates the early melanosome homeostasis required for physiological amyloid formation (doi:10.1242/jcs.229500)

There was an error in J. Cell Sci. (2019) 132, [jcs229500][1] ([doi:10.1242/jcs.229500][2]). The DMSO lanes in [Fig. 2][3]C and D were duplicated in [Fig. 2][3]E and F, respectively, which contravenes our image presentation guidelines. The authors supplied full blots for all these panels and

Noir II – the art of murder

![Graphic][1] Red Fox was parked in a plaid, upholstered lounge chair under the flare of a lobby light like a sample on a confocal stage and gave me the nose-to-toe before flashing her dazzling smile. “Hiya, Mole,” she said. “You look terrible.” “Yeh, crummy beds in this half star

Thank you to our peer reviewers in 2018

There is currently much discussion and criticism about the peer review process and what form it should take moving forward. For Journal of Cell Science, however, high-quality peer review is still at the heart of the academic publication process and is one of the means by which our academic editors

Correction: LC3-associated phagocytosis at a glance (doi:10.1242/jcs.222984)

There was an error in J. Cell Sci. (2019) 132, [jcs222984][1] ([doi:10.1242/jcs.222984][2]). Unfortunately, the second bilayer membrane in the diagram illustrating autophagosome formation was omitted. The print and online versions of the article and poster have been corrected accordingly. This

Synthetic lethality of cytolytic HSV-1 in cancer cells with ATRX and PML deficiency

Cancers that utilize the alternative lengthening of telomeres (ALT) mechanism for telomere maintenance are often difficult to treat and have a poor prognosis. They are also commonly deficient for expression of ATRX protein, a repressor of ALT activity, and a component of promyelocytic leukemia nuclear bodies (PML NBs) that are required for intrinsic immunity to various viruses...

Meeting report – Building the Cell 2018

Cell biologists from all around the world gathered in Paris on the 26 to 28 September 2018 to participate in the 3rd international meeting ‘Building the Cell’. It was organized by Hélène Barelli, Arnaud Echard, Thierry Galli, Florence Niedergang, Manuel Théry and Marie Hélène Verlhac on behalf of the French Society for Cell Biology (SBCF) at the Institut Pasteur. Around 230...

Noir I – the anti-executioner

![Graphic][1] It was cold. Cold as an editor's smile when I'm pitching our latest work in the hotel bar at a meeting after hours. The single light over my desk cast a flickering circle of faded white that did not brighten my mood, or make the western blots in Figure 3 any clearer. The rain

The N-cadherin interactome in primary cardiomyocytes as defined using quantitative proximity proteomics

The junctional complexes that couple cardiomyocytes must transmit the mechanical forces of contraction while maintaining adhesive homeostasis. The adherens junction (AJ) connects the actomyosin networks of neighboring cardiomyocytes and is required for proper heart function. Yet little is known about the molecular composition of the cardiomyocyte AJ or how it is organized to...

Enigma proteins regulate YAP mechanotransduction

Human cells can sense mechanical stress acting upon integrin adhesions and respond by sending the YAP (also known as YAP1) and TAZ (also known as WWTR1) transcriptional co-activators to the nucleus to drive TEAD-dependent transcription of target genes. How integrin signaling activates YAP remains unclear. Here, we show that integrin-mediated mechanotransduction requires the...

Parlez vous immunology?

![Graphic][1] Ana-Maria Lennon-Duménil As cell biologists, we may not understand all the specifics of each other's fields but, for the most part, we all speak a fairly common language: blots, imaging, pulldowns, antibodies, knockouts, RNAi, organelles, forces, migration, trafficking and,

Correction: Disruption of Rab8a and Rab11a causes formation of basolateral microvilli in neonatal enteropathy (doi: 10.1242/jcs.201897)

There were errors published in J. Cell Sci. (2017) 130, [2491-2505][1] ([[doi: 10.1242/jcs.201897][3]][3]). In [Fig. 1][3]D, the labels of H&E histology images for Rab8afl/+;Rab11afl/fl;Vil-cre and Rab8afl/fl;Rab11afl/+;Vil-cre (middle panels) were switched. In addition, images in [Fig. 1][3]