Wiener klinische Wochenschrift

http://link.springer.com/journal/508

List of Papers (Total 307)

Hypoalbuminemia as predictor of recurrence of Clostridium difficile infection

SummaryBackgroundNovel drugs for Clostridium difficile (C. difficile) infections have been proven to reduce recurrent infections. Because of their high financial costs, identification of patients at high risk for recurrence is essential to provide optimal treatment. The ATLAS score’s ability to predict 90-day recurrence, disease complications and 1‑year all-cause mortality was...

Competency in medical history taking—the training physicians’ view

SummaryBackgroundBecause effective communication skills are crucial for every physician, this study evaluated students’ competence to take a sufficient medical history. This ability was measured via reports from the students’ supervising and training physicians.MethodsA total of 24 physicians from several different departments were interviewed‚ and a stratification of medical...

Comparison of native myocardial T1 and T2 mapping at 1.5T and 3T in healthy volunteers

SummaryBackgroundMyocardial native T1 and T2 mapping are promising techniques for quantitative assessment of diffuse myocardial pathologies; however, due to conflicting data regarding normal values, routine clinical implementation of this method is still challenging.MethodsTo evaluate this situation during daily clinical practice the characteristics of normal values obtained in...

Correlation of affective temperament and psychiatric symptoms in palliative care cancer patients

SummaryBackgroundPsychiatric symptoms are common in terminally ill patients. Studies linking temperamental traits and psychiatric disorders in patients suffering from advanced disease are rare. This study investigated the influence of temperament on depression and anxiety in palliative care cancer patients.MethodsA total of 53 patients at the palliative care unit (PCU) of the...

Austrian consensus guidelines on imaging requirements prior to hepatic surgery and during follow-up in patients with malignant hepatic lesions

SummaryRapid advances in imaging technology have improved the detection, characterization and staging of colorectal liver metastases, hepatocellular carcinoma and cholangiocarcinoma. A variety of imaging modalities are available and play a pivotal role in the work-up of patients, particularly as imaging findings determine resectability. Surgery often represents the only measure...

Non-vitamin K antagonist oral anticoagulants in patients with an increased risk of bleeding

SummaryThe non-vitamin K antagonist oral anticoagulants (NOACs) have considerably changed clinical practice and are increasingly being used as an alternative to vitamin K antagonists (VKAs) for 3 main reasons: 1) an improved benefit-risk ratio (in particular lower rates of intracranial bleeding), 2) a more predictable effect without the need for routine monitoring, and 3) fewer...

Lowering blood pressure in primary care in Vienna (LOW-BP-VIENNA)

SummaryBackgroundIn Austria only 41% of patients with treated hypertension (HTN) have their blood pressure (BP) controlled. This study investigated a strategy to improve BP control in primary care.MethodsGeneral practitioners (GPs) were randomized to interventional care vs. standard care and included patients with uncontrolled office BP > 140/90 mm Hg. In interventional care...

Changes in health parameters in older lay volunteers who delivered a lifestyle-based program to frail older people at home

SummaryObjectiveTo measure health effects in lay volunteers who made home visits consisting of social interaction, nutritional and physical exercise interventions to pre-frail and frail older people (trial registration ClinicalTrials.gov, NCT01991639).MethodsAfter baseline, participants were followed-up at 12 (V1) and 24 (V2) weeks. A one-repetition maximum (1-RPM) and handgrip...

Prioritizing information topics for relatives of critically ill patients

SummaryA patient’s admission to an intensive care unit (ICU) has a significant impact on family members and other relatives. In order for them to be able to cope with such a stressful situation, the availability of appropriate understandable and accessible information is crucial. The information asymmetry between relatives and medical professionals may adversely affect...

Microbiological features distinguishing Lyme disease and relapsing fever spirochetes

SummaryThe recent proposal of splitting the genus Borrelia into two genera in the newly formed family of Borreliaceae, i. e. Borrelia and Borreliella has motivated us to reflect upon how these organisms has been characterized and differentiated. This article therefore aims to take a closer look on the biology and virulence attributes of the two suggested genera, i. e. those...

Long-term outcomes after acute hypercapnic COPD exacerbation

SummaryBackgroundNon-invasive ventilation (NIV) is used to treat acute hypercapnic respiratory failure (AHRF) in patients with chronic obstructive pulmonary disease (COPD); however, long-term outcomes following discharge are largely unknown. This study aimed to characterize long-term outcomes and identify associated markers in patients with COPD after surviving the first episode...

Secondary dementia due to Lyme neuroborreliosis

SummaryDementia-like syndromes are rare manifestations of Lyme neuroborreliosis. The clinical patterns are summarized using our own cases and case reports from the literature, which were diagnosed as definite Lyme neuroborreliosis according to the European guidelines. The cases disclose signs of subcortical dementia that occur more rapidly than in patients suffering from primary...

Ruxolitinib therapy for myelofibrosis in Austria

SummaryThe oral Janus associated kinase (JAK1/2) inhibitor ruxolitinib has been available for treatment of patients with intermediate or high-risk myelofibrosis in Europe since 2012. Since its introduction, the expertise of prescribing doctors with respect to ruxolitinib function, efficacy and adverse effects has consistently been augmented, resulting in therapy modalities that...

Ludwig Boltzmann Cluster Oncology (LBC ONC): first 10 years and future perspectives

SummaryIn 2008 the Ludwig Boltzmann Cluster Oncology (LBC ONC) was established on the basis of two previous Ludwig Boltzmann Institutes working in the field of hematology and cancer research. The general aim of the LBC ONC is to improve treatment of hematopoietic neoplasms by eradicating cancer-initiating and disease-propagating cells, also known as leukemic stem cells (LSC) in...

Official definitions for undesirable medical events

SummaryBackgroundIn Austria, elaborate definitions exist for the undesirable medical events side effect, adverse event, complication and medical malpractice. We aimed at investigating whether the official definitions for the abovementioned terms can be understood by a sample population representing a cross-section of the Austrian population.MethodsIn this study 1021 Austrian...

Anticoagulation in non-malignant portal vein thrombosis is safe and improves hepatic function

SummaryBackgroundNon-malignant portal vein thrombosis (PVT) is common in patients with advanced liver disease. Anticoagulation (AC) increases the chances of recanalization and may improve liver function in patients with cirrhosis.AimWe retrospectively assessed the course of non-malignant PVT in patients receiving AC.MethodsParameters related to hepatic injury (aspartate...