BMC Research Notes

http://link.springer.com/journal/13104

List of Papers (Total 6,424)

Level of unintended pregnancy among reproductive age women in Bahir Dar city administration, Northwest Ethiopia

ObjectiveThe objective of this study was to determine the prevalence and determinants of unintended pregnancy among reproductive age women in Bahir Dar town, Northwest Ethiopia.ResultThe prevalence of unintended pregnancy was 15.8% (95% CI 13.8%–17.7%). Single women (AOR 0.18; 95% CI 0.08–0.40), women living away from their husband (AOR 4.18; 95% CI 2.64–6.61) and women with no...

Determinants of burnout syndrome among nurses in Cameroon

ObjectivesBurnout syndrome is common amongst medical personnel. The objective of this study was to identify determinants of burnout syndrome among nurses in the north west and south west regions of Cameroon.ResultsA cross-sectional analysis during the months of January–June 2018 was carried out recruiting nurses consecutively after consent from state-owned and private hospitals...

A neural network analysis of Lifeways cross-generation imputed data

ObjectivesNeural networks are a powerful statistical tool that use nonlinear regression type models to obtain predictions. Their use in the Lifeways cross-generation study that examined body mass index (BMI) of children, among other measures, is explored here. Our aim is to predict the BMI of children from that of their parents and maternal and paternal grandparents. For...

Preparation of lyophilized recombinant prion protein for TSE diagnosis by RT-QuIC

ObjectiveTransmissible spongiform encephalopathies (TSEs) are a group of fatal neurodegenerative diseases, often referred as prion diseases. TSEs result from the misfolding of the cellular prion protein (PrPC) into a pathogenic form (PrPSc) that accumulates in the brain and lymphatic tissue. Amplification based assays such as real-time quaking induced conversion allow us to...

Using a birth cohort to study brain health and preclinical dementia: recruitment and participation rates in Insight 46

ObjectiveIdentifying and recruiting people with early pre-symptomatic Alzheimer’s disease to neuroimaging research studies is increasingly important. The extent to which results of these studies can be generalised depends on the recruitment and representativeness of the participants involved. We now report the recruitment and participation patterns from a neuroscience sub-study...

The gingival health status of 8–12 year-old children in Damascus city in Syria during the Syrian Crisis: a cross-sectional epidemiological oral health survey

ObjectiveThe aim of this study was to assess the current gingival health status in children aged 8–12 years in Damascus city. No contemporary data was available with an immense need for studies evaluating the gingival health status in Syrian children, especially under the current circumstances of the Syrian crisis.ResultsThe study followed the school-based health survey model...

The status and health burden of neurocysticercosis in Mbulu district, northern Tanzania

ObjectiveThe objective of this study was to assess the extent and health burden of neurocysticercosis in the general community of the Mbulu district, northern Tanzania. About 1051 randomly select participants were screened for human cysticercosis. The Cysticercus Western Blot IgG and Computed Tomography scan were used to detect infection by cysticerci. The DALYs was used to...

Magnitude of fetal macrosomia and its associated factors at public health institutions of Hawassa city, southern Ethiopia

ObjectivesThis study aimed to determine the magnitude of fetal macrosomia and associated factors at public health institutions of Hawassa city, southern Ethiopia.ResultsIn this study, the magnitude of fetal macrosomia found to be 11.86%. Being a male (AOR = 2.2, 95% CI 1.1–4.2), ≥ 37 weeks gestational age (AOR = 6.0, 95% CI 3.1–11.1) and having previous history of fetal...

A genome-wide dsRNA library screen for Drosophila genes that regulate the GBP/phospholipase C signaling axis that links inflammation to aging

ObjectiveInvertebrates are productive models for understanding how inflammation, metabolism and aging are intertwined. We have deployed a dsRNA library screen to search for genes in Drosophila melanogaster—and hence identify human orthologs—that encode participants in a G-protein coupled, Ca2+-signaling pathway that regulates inflammation, metabolism and lifespan.ResultsWe...

Patterns of common skin infections among children living with HIV/AIDS in Hawassa City, Ethiopia: a cross sectional study

ObjectivesSkin disorders are the most common health problems seen among HIV positive patients. It presents with a variety of manifestations which can cause significant morbidity. This study was aimed to assess the prevalence of common skin problems among children living with HIV/AIDS at Hawassa University Comprehensive Specialized Hospital, Hawassa, Ethiopia, 2017/2018. Hospital...

Association between cesarean section and constipation in infants: the Japan Environment and Children’s Study (JECS)

ObjectiveThere have been increasing reports on the association between cesarean section (C-section) and the subsequent development of diseases in infants. C-section affects the diversity of microbiota in the infant’s gut. In the present study, we investigated the association between infants delivered by C-section and the development of constipation at 1 year old due to altered...

Connecting nutrition composition measures to biomedical research

ObjectivesBiomedical research is gaining ground on human disease through many types of “omics”, which is leading to increasingly effective treatments and broad applications for precision medicine. The majority of disease treatments still revolve around drugs and biologics. Although food is consumed in much higher quantities, we understand very little about how the human body...

Anaemia requiring red blood cell transfusion is associated with unfavourable 90-day survival in surgical patients with sepsis

ObjectiveThe mortality associated with sepsis remains unacceptably high, despite modern high-quality intensive care. Based on the results from previous studies, anaemia and its management in patients with sepsis appear to impact outcomes; however, the transfusion policy is still being debated, and the ideal approach may be extremely specific to the individual. This study aimed to...

Data on whole genome sequencing of the oomycete Pythium insidiosum strain CBS 101555 from a horse with pythiosis in Brazil

ObjectivesThe oomycete Pythium insidiosum infects humans and animals worldwide, and causes the life-threatening condition, called pythosis. Most patients lose infected organs or die from the disease. Comparative genomic analyses of different P. insidiosum strains could provide new insights into its pathobiology, and can lead to discovery of an effective treatment method. Several...

Reliability of birth weight recall by parent or guardian respondents in a study of healthy adolescents

ObjectiveBirth weight, which can be an indicator for risk of chronic diseases throughout the lifespan, is one of the most commonly used measures in the study of developmental origins of health and disease. There is limited information on the reliability of parent/guardian reported birth weight by race or by respondent type (i.e., mother, father, other caregiver).ResultsBirth...

Evaluation of the acute flaccid paralysis (AFP) surveillance system in Mwenezi district, Masvingo, 2018: a descriptive study

ObjectivesPoliomyelitis is an infectious disease caused by the polio virus which affects mostly young children below the age of 15 years. For surveillance children with acute flaccid paralysis (AFP) are tracked. In Zimbabwe every district should report two cases per 100,000 population of children under the age of 15 years old. In 2017, Mwenezi district failed to detect any AFP...

Prevalence and associated factors of hypertension among adult patients in Felege-Hiwot Comprehensive Referral Hospitals, northwest, Ethiopia: a cross-sectional study

ObjectiveThe main objective of this study was to assess the prevalence and factors associated with hypertension among adult patients in Felege-Hiwot Comprehensive Referral Hospital, northwest Ethiopia, 2018.ResultThe prevalence of hypertension in the current study area was 27.3%. Known history of cardiac problems [AOR = 6.9; 95% CI (1.24, 11.44)], alcohol consumption [AOR = 2.2...

Young maternal age is a risk factor for child undernutrition in Tamale Metropolis, Ghana

ObjectiveMalnutrition is a common cause of morbidity and mortality in children. The aim of this study was to compare the nutritional status of children under 5 years of teenage and adult mothers in Tamale Metropolis, Ghana. A case–control study involving 300 (150 cases, 150 controls) mother–child pairs was carried out. A questionnaire was used to collect data on socio-demographic...

A prospective study on dual time 18F-FDG-PET/CT in high-risk prostate cancer patients

ObjectiveThis proof of concept study investigated whether dual time point FDG-PET/CT with image acquisition after 1 and 3 h could be useful in preoperative staging of patients undergoing robot-assisted radical prostatectomy and extended pelvic lymph node dissection for high-risk prostate cancer.ResultsTwenty patients with high-risk prostate cancer underwent dual time point FDG...

Pregnant women adherence level to antenatal care visit and its effect on perinatal outcome among mothers in Tigray Public Health institutions, 2017: cohort study

ObjectiveTo assess pregnant women adherence level to antenatal care visit and its effect on perinatal outcome among mothers in Tigray Public Health institutions, 2017.ResultsThe overall adherence level of the women towards to antenatal care visit was 49.9% and incidence of PPH, still birth, early neonatal death, late neonatal death and low birth weight complication was 4.3%, 2.3...

Intimate partner violence and depression among pregnant women in the North west region of Cameroon: a research proposal

ObjectivesIntimate partner violence (IPV) in pregnancy is a major public health concern due to its harmful effects on both the mother and the unborn foetus. In this study, we aim to assess the prevalence and correlates of both IPV and depression in pregnant women in the northwest region of Cameroon. Specifically: (1) To determine the prevalence of IPV in a group of pregnant women...

Manifolds boosting severe acute malnutrition burden among children in and around Wolaita Zone, Southern Ethiopia: mini-review

ObjectivesSevere acute malnutrition (SAM) has been considered as the complex nutritional problem within developing countries. Alleviating its occurrence also exists in an anxiety. A series of studies were conducted to disclose evidences and documented by here author. Moreover key messages were abstracted with this review easing access of texts.ResultsDue to pitiable sanitary...

Proportion and factors of death among preterm neonates admitted in University of Gondar comprehensive specialized hospital neonatal intensive care unit, Northwest Ethiopia

ObjectiveNeonatal mortality accounts for 43% of under-five child mortality in Ethiopia where preterm is the second leading cause of neonatal death and steadily increased in low-income countries. Therefore, assessing the proportion of death and associated factors among preterm neonates has a paramount importance in designing an effective strategy to intervene and achieve...

Risk factors for human brucellosis among a pastoralist community in South-West Kenya, 2015

ObjectiveBrucellosis is one of the top five priority zoonosis in Kenya because of the socio-economic burden of the disease, especially among traditional, livestock keeping communities. We conducted a 1 year, hospital based, unmatched case–control study to determine risk factors for brucellosis among Maasai pastoralists of Kajiado County in 2016. A case was defined by a clinical...

Validation of extracellular ligand–receptor interactions by Flow-TriCEPS

ObjectiveThe advent of ligand-based receptor capture methodologies, allows the identification of unknown receptor candidates for orphan extracellular ligands. However, further target validation can be tedious, laborious and time-consuming. Here, we present a methodology that provides a fast and cost-efficient alternative for candidate target verification on living cells.ResultsIn...