BMC Research Notes

http://link.springer.com/journal/13104

List of Papers (Total 6,571)

A case series of venous thromboembolic disease in a semi-urban setting in Cameroon

ObjectiveOur goal was to study the clinical characteristics, risk factors and outcome of patients admitted for venous thromboembolism (VTE) in the medical unit of the Buea Regional Hospital, Cameroon between 1st July 2016 and 30th November 2017.ResultsTwenty-two patients were admitted for VTE. There were 12 (54.4%) men. The mean age was 54.9 ± 13.9 years (range: 31–77 years). The...

The effect of the health transformation plan on cesarean section in Iran: a systematic review of the literature

ObjectiveCesarean section (CS) is one of the most common surgical procedures in the world. In developed and developing countries, CS has grown significantly over the past decades. The Iranian Ministry of Health and Medical Education has developed a health transformation plan (HTP) in order to reduce CS rate and promote vaginal delivery. This study was conducted with the aim of...

Prevalence of dual contraceptive use and associated factors among HIV positive women at University of Gondar Hospital, Northwest Ethiopia

ObjectiveDual contraceptive is the use of male condom besides any modern contraceptive. It reduces parent to child transmission of HIV and other sexually transmitted infections between partners. The aim of this study was to investigate the prevalence and associated factors of dual contraceptive use among HIV positive women at University of Gondar Hospital, North West Ethiopia...

Healthcare workers knowledge and diagnostic practices: a need for dengue and chikungunya training in Moshi Municipality, Kilimanjaro Tanzania

ObjectiveDengue and chikungunya virus diseases are becoming an increasingly important global health threats and are continuously expanding their geographical range. The study aims to investigate knowledge and diagnostic practice of dengue and chikungunya fever among healthcare workers in Moshi Municipality.ResultsMost of healthcare workers heard of chikungunya and dengue 146 (71...

Simultaneous extraction of mRNA and microRNA from whole blood stabilized in tempus tubes

ObjectiveStudies of mRNA and miRNA expression profiling increasingly use stabilized whole blood. Commercial RNA extraction kits do not provide information about the simultaneous recovery of both mRNA and miRNA. This study evaluated yield, quality, integrity and representation of mRNA and miRNA from whole blood stabilized in Tempus tubes using three RNA extraction kits; two filter...

ERG oncoprotein expression in prostatic acinar adenocarcinoma; clinicopathologic significance

ObjectivesT/E fusion results in constitutive expression of ERG oncoprotein resulting in enhanced proliferation and invasive potential of prostatic cancer cells. In the present study we aimed to evaluate the ERG overexpression in 78 cases prostate acinar adenocarcinoma and its association with other prognostic parameters.ResultsERG protein expression was noted in 39.7% (31 cases...

Study of biofilm formation and antibiotic resistance pattern of gram-negative Bacilli among the clinical isolates at BPKIHS, Dharan

ObjectivesGram-negative bacilli are the common causative agents for community-acquired, nosocomial and opportunistic infections. The recent upsurge of biofilm, as well as beta-lactamases producing strains, have synergistically led to the extensive dissemination of multi-drug resistant gram-negative bacilli. This study was carried out with an intention to detect the biofilm...

Evaluating the Published Critical Care Research from the World Health Organization Eastern Mediterranean Region

ObjectivesEvaluation of published research in a region provides insight into relevant aspects of clinical care and research priorities. This study aimed to provide a comprehensive assessment of the type of critical care research published in the World Health Organization Eastern Mediterranean region (EMR) over a 10-year period.ResultsDuring the study period (2007–2016), the...

An efficient prototype method to identify and correct misspellings in clinical text

ObjectiveMisspellings in clinical free text present challenges to natural language processing. With an objective to identify misspellings and their corrections, we developed a prototype spelling analysis method that implements Word2Vec, Levenshtein edit distance constraints, a lexical resource, and corpus term frequencies. We used the prototype method to process two different...

Analysis of a structured intronic region of the LMP2 pre-mRNA from EBV reveals associations with human regulatory proteins and nuclear actin

ObjectiveThe pre-mRNA of the Epstein–Barr virus LMP2 (latent membrane protein 2) has a region of unusual RNA structure that partially spans two consecutive exons and the entire intervening intron; suggesting RNA folding might affect splicing—particularly via interactions with human regulatory proteins. To better understand the roles of protein associations with this structured...

Willingness to join community based health insurance and its determinants in East Gojjam zone, Northwest Ethiopia

ObjectiveThe main purpose of this research was to determine the magnitude of willingness to join to community based health insurance (CBHI) and to identify factors associated with it.ResultsA total of 604 study participants responded for the interviews, making the response rate 98.2%. All in all, 492 (81.5%) of the study participant households were willing to join the CBHI scheme...

Medical students’ preferences towards learning resources and their study habits at King Abdulaziz University, Jeddah, Saudi Arabia

ObjectiveThe purpose of the present study was to explore why our medical students are avoiding the study of professional textbooks. We conducted this study from 10th March to 15th May 2017 at the King Abdulaziz University (KAU), Jeddah, to investigate their preferences towards learning resources, their study habits and correlation of academic achievements as a result of these...

Crude extracts of Sesamum Indicum roots used as anthraquinone source effect on pulping with sodium hydroxide of Sudanese bagasse

The objectivesThe work was carried out for extraction of natural anthrasesamones from roots of Sesamum Indicum using different organic solvents and utilization of extracts as catalyst in pulping with sodium hydroxide for a by-product of sugar industry (Sudanese bagasse).ResultsSesamum Indicum roots when extracted with ethanol, it gave the highest extracts yield % (0.964...

Distribution of out of pocket health expenditures in a sub-Saharan Africa country: evidence from the national survey of household standard of living, Côte d’Ivoire

ObjectiveThe purpose and objective of our research is to identify the determinants of the out of pocket (OOP) health expenditures in the population of Ivory Coast and the ratios across three different area; Abidjan, the rural and urban area. We used data from the 2015 standard households living survey conducted by the National Institute of Statistic.ResultsAbout 6315 (13.3%) of...

Distribution of acquired antibiotic resistance genes among Enterococcus spp. isolated from a hospital in Baotou, China

ObjectiveThis study investigated the distribution of acquired antibiotic resistance genes in Enterococcus species isolated from clinical patients in Baotou, China.ResultA total of 73 enterococca lisolates from clinical samples were collected from December 2016 to September 2017. Of the 73 enterococcal isolates, 36 (49.3%), 35 (47.9%), 1 (1.4%), and 1 (1.4%) were identified as E...

High incidence of type III secretion system associated virulence factors (exoenzymes) in Pseudomonas aeruginosa isolated from Iranian burn patients

ObjectiveThe present study aimed to determine the prevalence of virulence factors and antimicrobial resistance profile of Pseudomonas aeruginosa strains isolated from Iranian burn patients.ResultsThis cross-sectional study performed on 100 P. aeruginosa isolates which were recovered from burn wound specimens in 2014–2015. All presumptive isolates were identified by standard...

Using Concept Maps to compare obesity knowledge between policy makers and primary care researchers in Canada

ObjectiveKnowledge transfer is the process of information sharing between researchers, knowledge users and policy makers. Globally, public policies about obesity do not reflect the complexity of what is known about the cause and effects of obesity. We used Concept Maps, a qualitative method that represents mental models, to compare the understanding of obesity between policy...

Periodic mild heat stimuli diminish extracellular matrix synthesis in pellet cultured human chondrocytes

ObjectiveThis study aimed to clarify the effects of periodic mild heat stimuli on extracellular matrix (ECM) synthesis of adult human chondrocytes in 3-dimensional pellet culture.ResultsHuman articular chondrocytes were subjected to pellet culture at 37 °C for 3 days. Thereafter, the pellets were divided into three groups: 32 °C group which was cultured at 32 °C without heat...

Status of metered dose inhaler technique among patients with asthma and its effect on asthma control in Northwest Ethiopia

ObjectiveIn Asthma management, poor handling of inhalation devices and wrong inhalation technique are associated with decreased medication delivery and poor disease control. The aim of this study was to assess the status of Metered dose inhaler technique, associated factors and its impact on Asthma control among adult patients with Asthma.ResultsThe mean duration of Asthma was 15...

Antimicrobial resistance genes in Salmonella and Escherichia coli isolates from chicken droppings in Nairobi, Kenya

ObjectiveIncrease in antimicrobial resistance is a threat to health sector globally. Surveillance on the spread and emergence of antimicrobial resistance is therefore invertible. This study investigated prevalence of Salmonella and Escherichia coli, molecularly characterized their antimicrobial resistance patterns and spread among resistant isolates from chicken droppings...

Triage knowledge and skills among nurses in emergency units of Specialized Hospital in Hawassa, Ethiopia: cross sectional study

ObjectiveThis study was aimed to assess knowledge and skills of triage and associated factors among nurses in emergency department of Hawassa University Comprehensive Specialized Hospital, South Ethiopia. Institutional based cross-sectional study design was conducted among 101 nurses from March 1–30, 2018. The data was coded and entered to SPSS version 22.0. Descriptive...

Community-Led Total Sanitation and the rate of latrine ownership

ObjectiveLack of sanitation affecting billions of people worldwide is a serious public health problem of Ethiopia. So, we aimed at examining the influence of community interventions on households’ latrine ownership status in Northwest Ethiopia.ResultsThe proportion of households owning latrines were 47% (95% CI 42.5, 52.0). Community Lead Total Sanitation practice in the kebele...

Comparing the EQ-5D-5L utility index based on value sets of different countries: impact on the interpretation of clinical study results

ObjectiveTo compare the country-specific value sets of the EQ-5D-5L utility index and to evaluate the impact on the interpretation of clinical study results. Six country value sets from Canada, England, Japan, Korea, Netherlands and Uruguay were obtained from literature. In addition, ten crosswalk value sets were downloaded from the EuroQol.org website.ResultsFor each of the 3125...

Time to initiate complementary feeding and associated factors among mothers with children aged 6–24 months in Tahtay Maichew district, northern Ethiopia

ObjectiveIn Ethiopia, only 51% of the infants start complementary feeding on time. Therefore this study is aimed to determine the time to initiate complementary feeding and associated factors among mothers with children aged 6–24 months in Tahtay Maichew district, northern Ethiopia. A retrospective follow up study was conducted among 639 mothers who had children aged 6–24 months...