European Radiology

https://link.springer.com/journal/330

List of Papers (Total 860)

Are semi-automated software program designed for adults accurate for the identification of vertebral fractures in children?

ObjectivesTo assess whether diagnostic accuracy of morphometric vertebral fracture (VF) diagnosis in children can be improved using AVERT™ (a 33-point semi-automated program developed for VF diagnosis in adults) compared with SpineAnalyzer™ (a 6-point program), which has previously been shown to be of insufficient accuracy.Materials and methodsLateral spine radiographs (XR) and...

High sensitivity and specificity of 4D-CTA in the detection of cranial arteriovenous shunts

PurposeIn a prospective cohort study, we evaluated the diagnostic accuracy of time-resolved CT angiography (4D-CTA) compared to digital subtraction angiography (DSA) for detecting cranial arteriovenous shunts.Material and methodsPatients were enrolled if a DSA had been ordered querying either a dural arteriovenous fistula (dAVF) or a cerebral arteriovenous malformation (bAVM...

Evaluation of single-view contrast-enhanced mammography as novel reading strategy: a non-inferiority feasibility study

BackgroundGuidelines recommend screening of high-risk women using breast magnetic resonance imaging (MRI). Contrast-enhanced mammography (CEM) has matured, providing excellent diagnostic accuracy. To lower total radiation dose, evaluation of single-view (1 V) CEM exams might be considered instead of double-view (2 V) readings as an alternative reading strategy in women who cannot...

Encouraging MSK imaging research towards clinical impact is a necessity: opinion paper of the European Society of Musculoskeletal Radiology (ESSR)

Radiology has not been spared in recent economic crises with a substantial reduction in the turnover of imaging equipment. These problems are exacerbated by increasing demand for healthcare across Europe. Therefore, using existing radiological services while rigorously following evidence-based guidelines might improve patient care. Thus, diagnostic pathways should be assessed not...

Inter- and intra-reader agreement for gadoxetic acid–enhanced MRI parameter readings in patients with chronic liver diseases

ObjectivesTo examine inter- and intra-observer agreement for four simple hepatobiliary phase (HBP)–based scores on gadoxetic acid (GA)–enhanced MRI and their correlation with liver function in patients with mixed chronic liver disease (CLD).MethodsThis single-center, retrospective study included 287 patients (62% male, 38% female, mean age 53.5 ± 13.7 years) with mixed CLD (20.9...

Can we reduce the workload of mammographic screening by automatic identification of normal exams with artificial intelligence? A feasibility study

PurposeTo study the feasibility of automatically identifying normal digital mammography (DM) exams with artificial intelligence (AI) to reduce the breast cancer screening reading workload.Methods and materialsA total of 2652 DM exams (653 cancer) and interpretations by 101 radiologists were gathered from nine previously performed multi-reader multi-case receiver operating...

Increased tortuosity of ACA might be associated with increased risk of ACoA aneurysm development and less aneurysm dome size: a computer-aided analysis

ObjectivesWe decided to perform computer-aided analysis of the anterior cerebral artery (ACA) to check for a potential correlation with anterior communicating artery (ACoA) aneurysm presence and growth.MethodsWe retrospectively analyzed the ACA anatomy of 121 patients with ACoA aneurysms along with 121 age, risk factors, and vessel side-matched control patients without an ACoA...

Computed tomographic colonography: how many and how fast should radiologists report?

ObjectivesTo determine if polyp detection at computed tomographic colonography (CTC) is associated with (a) the number of CTC examinations interpreted per day and (b) the length of time spent scrutinising the scan.MethodsRetrospective observational study from two hospitals. We extracted Radiology Information System data for CTC examinations from Jan 2012 to Dec 2015. For each...

Patient preferences for whole-body MRI or conventional staging pathways in lung and colorectal cancer: a discrete choice experiment

ObjectivesTo determine the importance placed by patients on attributes associated with whole-body MRI (WB-MRI) and standard cancer staging pathways and ascertain drivers of preference.MethodsPatients recruited to two multi-centre diagnostic accuracy trials comparing WB-MRI with standard staging pathways in lung and colorectal cancer were invited to complete a discrete choice...

Application of a deep learning algorithm for detection and visualization of hip fractures on plain pelvic radiographs

ObjectiveTo identify the feasibility of using a deep convolutional neural network (DCNN) for the detection and localization of hip fractures on plain frontal pelvic radiographs (PXRs).Summary of background dataHip fracture is a leading worldwide health problem for the elderly. A missed diagnosis of hip fracture on radiography leads to a dismal prognosis. The application of a DCNN...

Ferumoxytol magnetic resonance angiography: a dose-finding study in patients with chronic kidney disease

ObjectivesFerumoxytol is an alternative to gadolinium-based compounds as a vascular contrast agent for magnetic resonance angiography (MRA), particularly for patients with chronic kidney disease (CKD). However, dose-related efficacy data are lacking. We aimed to determine the optimal (minimum effective) dose of ferumoxytol for MRA in patients with CKD.MethodsFerumoxytol-enhanced...

Comparison of 3D endoanal ultrasound and external phased array magnetic resonance imaging in the diagnosis of obstetric anal sphincter injuries

ObjectivesThe gold standard of postpartum anal sphincter imaging has been the 3D endoanal ultrasound (EAUS). Development of magnetic resonance imaging (MRI) has allowed anal sphincter evaluation without the use of endoanal coils. The aim of this study is to compare these two modalities in diagnosing residual sphincter lesions post obstetric anal sphincter injury (OASI...

Differentiation of two subtypes of intrahepatic cholangiocarcinoma: imaging approach

Key Points • Mass-forming intrahepatic cholangiocarcinoma can be divided into two subgroups, namley, perihilar and peripheral types. • These two significantly differ in clinico-biological behaviors, and in patients’ prognosis as well. • This differentiation may be achieved solely by contrast-enhanced MR imaging findings.

Multi-detector CT imaging: impact of virtual tube current reduction and sparse sampling on detection of vertebral fractures

PurposeTo systematically evaluate the effects of virtual tube current reduction and sparse sampling on image quality and vertebral fracture diagnostics in multi-detector computed tomography (MDCT).Materials and methodsIn routine MDCT scans of 35 patients (80.0% females, 70.6 ± 14.2 years, 65.7% showing vertebral fractures), reduced radiation doses were retrospectively simulated...

T2 mapping of the meniscus is a biomarker for early osteoarthritis

PurposeTo evaluate in vivo T2 mapping as quantitative, imaging-based biomarker for meniscal degeneration in humans, by studying the correlation between T2 relaxation time and degree of histological degeneration as reference standard.MethodsIn this prospective validation study, 13 menisci from seven patients with radiographic knee osteoarthritis (median age 67 years, three males...

Low PI-RADS assessment category excludes extraprostatic extension (≥pT3a) of prostate cancer: a histology-validated study including 301 operated patients

ObjectivesTo evaluate whether low PI-RADS v2 assessment categories are effective at excluding extraprostatic extension (EPE) of prostate cancer (≥pT3a PCa).MethodsThe local institutional ethics committee approved this retrospective analysis of 301 consecutive PCa patients. Patients were classified as low- or intermediate/high-risk based on clinical parameters and underwent pre...

Adaptive statistical iterative reconstruction (ASIR) affects CT radiomics quantification in primary colorectal cancer

ObjectivesTo investigate whether adaptive statistical iterative reconstruction (ASIR), a hybrid iterative CT image reconstruction algorithm, affects radiomics feature quantification in primary colorectal cancer compared to filtered back projection. Additionally, to establish whether radiomics from single-slice analysis undergo greater change than those from multi-slice analysis...

Defining the incremental value of 3D T2-weighted imaging in the assessment of prostate cancer extracapsular extension

ObjectivesTo assess the added value of 3D T2-weighted imaging (T2WI) over conventional 2D T2WI in diagnosing extracapsular extension (ECE).MethodsSeventy-five patients undergoing 3-T MRI before radical prostatectomy were included. PI-RADS ≥ 4 lesions were assessed for ECE on 2D T2W images using a 5-point Likert scale (1 = no ECE, 5 = definite ECE) and the length of tumour...

Cortical cerebral blood flow in ageing: effects of haematocrit, sex, ethnicity and diabetes

ObjectivesCerebral blood flow (CBF) estimates from arterial spin labelling (ASL) show unexplained variability in older populations. We studied the impact of variation of haematocrit (Hct) on CBF estimates in a tri-ethnic elderly population.Materials and methodsApproval for the study was obtained from the Fulham Research Ethics Committee and participants gave written informed...

Exploring quantitative group-wise differentiation of Alzheimer’s disease and behavioural variant frontotemporal dementia using tract-specific microstructural white matter and functional connectivity measures at multiple time points

ObjectivesThis study explored group-wise quantitative measures of tract-specific white matter (WM) microstructure and functional default mode network (DMN) connectivity to establish an initial indication of their clinical applicability for early-stage and follow-up differential diagnosis of Alzheimer’s disease (AD) and behavioural variant frontotemporal dementia (bvFTD...

Comparison between dynamic gadoxetate-enhanced MRI and 99mTc-mebrofenin hepatobiliary scintigraphy with SPECT for quantitative assessment of liver function

ObjectivesTo compare Gd-EOB-DTPA dynamic hepatocyte-specific contrast-enhanced MRI (DHCE-MRI) with 99mTc-mebrofenin hepatobiliary scintigraphy (HBS) as quantitative liver function tests for the preoperative assessment of patients undergoing liver resection.MethodsPatients undergoing liver surgery and preoperative assessment of future remnant liver (FRL) function using 99mTc...

Standardised reports with a template format are superior to free text reports: the case for rectal cancer reporting in clinical practice

PurposeRectal cancer staging with magnetic resonance imaging (MRI) allows accurate assessment and preoperative staging of rectal cancers. Therefore, complete MRI reports are vital to treatment planning. Significant variability may exist in their content and completeness. Template-style reporting can improve reporting standards, but its use is not widespread. Given the...