OncoTargets and Therapy

https://www.dovepress.com/oncotargets-and-therapy-archive23

List of Papers (Total 2,044)

Overexpression of lncRNA PTENP1 suppresses glioma cell proliferation and metastasis in vitro

Overexpression of lncRNA PTENP1 suppresses glioma cell proliferation and metastasis in vitro Su Hu,1,* Li Xu,1,2,* Lihua Li,1 Dongdong Luo,1 Hailin Zhao,1 Dan Li,1 Biao Peng1 1Department of Neurosurgery, The Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Guangzhou 510095, Guangdong, People’s Republic of China; 2Department of Neurosurgery, The Central...

Upregulation of circulating miR130a is correlated with development of Barrett’s esophagus and esophageal adenocarcinoma

Upregulation of circulating miR130a is correlated with development of Barrett's esophagus and esophageal adenocarcinoma Li Wang,1 Feng Ji,1 Gang Liu,2 Wei Wang,3,4 Zhitong Li,1 Yongqiang Yue,1 Zhonggao Wang1,5,6 1Department of Interventional Radiology, First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China; 2Department of Center for Clinical Single Cell...

The effect of additional chemotherapy on high-risk prostate cancer: a systematic review and meta-analysis

The effect of additional chemotherapy on high-risk prostate cancer: a systematic review and meta-analysis Junru Chen,* Xingming Zhang,* Guangxi Sun, Jinge Zhao, Jiandong Liu, Peng Zhao, Jindong Dai, Pengfei Shen, Hao Zeng Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu 610041, China *These authors contributed equally to this work...

Risk factors for lymph node metastasis and the impact of adjuvant chemotherapy on ductal carcinoma in situ with microinvasion: a population-based study

Risk factors for lymph node metastasis and the impact of adjuvant chemotherapy on ductal carcinoma in situ with microinvasion: a population-based study Cong Chen,1,2 Shumin Huang,3 Aihua Huang,2,4 Yunlu Jia,1,2 Ji Wang,1,2 Zeqin Zhang,1,2 Misha Mao,1,2 Linbo Wang,1,2 Jichun Zhou1,2 1Department of Surgical Oncology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine...

miRNA-641 inhibits the proliferation, migration, and invasion and induces apoptosis of cervical cancer cells by directly targeting ZEB1

miRNA-641 inhibits the proliferation, migration, and invasion and induces apoptosis of cervical cancer cells by directly targeting ZEB1 Rui Yao, Huzhong Zheng, Liqun Wu, Pingsheng Cai Department of Obstetrics and Gynecology, Wenzhou Hospital of Integrated Traditional Chinese and Western Medicine, Wenzhou 325000, Zhejiang, People’s Republic of China Background: miRNAs have been...

Resveratrol induces apoptosis in human melanoma cell through negatively regulating Erk/PKM2/Bcl-2 axis

Resveratrol induces apoptosis in human melanoma cell through negatively regulating Erk/PKM2/Bcl-2 axis Hailong Zhao,1 Limin Han,1 Yi Jian,2 Yuntao Ma,3 Wanyue Yan,3 Xiaowen Chen,1 Haiyan Xu,1 Lijuan Li1 1Department of Pathophysiology, Zunyi Medical University, Zunyi, Guizhou Province 563000, People’s Republic of China; 2The First Clinical Institute, The School of Medicine and...

MicroRNA-302a-3p suppresses hepatocellular carcinoma progression by inhibiting proliferation and invasion

MicroRNA-302a-3p suppresses hepatocellular carcinoma progression by inhibiting proliferation and invasion Ying Ye,1,* Yanan Song,1,* Juhua Zhuang,1 Guoyu Wang,1 Jing Ni,1 Suiliang Zhang,2 Wei Xia1 1Department of Nuclear Medicine, The Seventh People’s Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, People’s Republic of China; 2Oncology Department, The...

Coincident primary breast lymphoma and gastrointestinal stromal tumor: case series and molecular mechanisms

Coincident primary breast lymphoma and gastrointestinal stromal tumor: case series and molecular mechanisms Ethan B Ludmir,1,* Tyler Gutschenritter,1,* Chelsea C Pinnix,1 Jillian R Gunther,1 Loretta J Nastoupil,2 Joseph D Khoury,3 L Jeffrey Medeiros,3 Bouthaina S Dabaja,1 Sarah A Milgrom1 1Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center...

Therapeutic decision based on molecular detection of resistance mechanism in an ALK-rearranged lung cancer patient: a case report

Therapeutic decision based on molecular detection of resistance mechanism in an ALK-rearranged lung cancer patient: a case report Elisa De Carlo,1,* Monica Schiappacassi,2,* Martina Urbani,3 Roberto Doliana,2 Gustavo Baldassarre,2 Valentina Da Ros,1 Sandra Santarossa,1 Emanuela Chimienti,1 Eleonora Berto,1 Lucia Fratino,1 Alessandra Bearz1 1Clinical Oncology Department, IRCCS CRO...

Transcatheter hepatic arterial chemoembolization plus cinobufotalin injection adjuvant therapy for advanced hepatocellular carcinoma: a meta-analysis of 27 trials involving 2,079 patients

Transcatheter hepatic arterial chemoembolization plus cinobufotalin injection adjuvant therapy for advanced hepatocellular carcinoma: a meta-analysis of 27 trials involving 2,079 patients Na Guo,* Yanyan Miao,* Mingzhong Sun Department of Hepatopathy, The Sixth People’s Hospital of Qingdao, Qingdao 266033, Shandong Province, China *These authors contributed equally to this work...

Overexpression of CD300A inhibits progression of NSCLC through downregulating Wnt/β-catenin pathway

Overexpression of CD300A inhibits progression of NSCLC through downregulating Wnt/beta-catenin pathway Ze Tang, Hongfei Cai, Rui Wang, Youbin Cui Department of Thoracic Surgery, The First Hospital of Jilin University, Changchun 130021, People’s Republic of China Background: CD300A, a type I transmembrane glycoprotein receptor, plays an important role in immune response. Recent...

Predictive value of positron emission tomography for the prognosis of molecularly targeted therapy in solid tumors

Predictive value of positron emission tomography for the prognosis of molecularly targeted therapy in solid tumors Xianhe Xie,1,* Huijuan Chen,1,* Haitao Yang,1 Heng Lin,2 Sijing Zhou,1 Ruifen Shen,1 Cuiping Lu,3 Liting Ling,1 Wanzun Lin,1 Ziyuan Liao1 1Department of Chemotherapy, The First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, People’s Republic of...

MicroRNA-486-3p directly targets BIK and regulates apoptosis and invasion in colorectal cancer cells

MicroRNA-486-3p directly targets BIK and regulates apoptosis and invasion in colorectal cancer cells Li Feng,1 Li Jing,1 Jing Han,1 Guiying Wang,2 Yan Liu,1 Xue Zhang,1 Yudong Wang,1 Feifei Wang,2 Hongqing Ma,2 Yibing Liu1 1Department of Medical Oncology, Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, China; 2Second Department of General Surgery, Fourth...

Clinical benefit from afatinib in an advanced squamous cell lung carcinoma patient harboring HER2 S310Y mutation: a case report

Clinical benefit from afatinib in an advanced squamous cell lung carcinoma patient harboring HER2 S310Y mutation: a case report Yan Gao,1 Aihong Zheng,2 Xiuming Zhu,2 Jia Song,3 Qian Xue2 1Department of Western Medicine, Wenxin Community Health Service Center, Hangzhou 310016, China; 2The Department of Medical Oncology, Zhejiang Provincial People’s Hospital, Hangzhou 310014...

Overexpression of NELFCD promotes colorectal cancer cells proliferation, migration, and invasion

Overexpression of NELFCD promotes colorectal cancer cells proliferation, migration, and invasion Shenglei Song, Daojiang Li, Chunxing Yang, Peicheng Yan, Yang Bai, Yi Zhang, Gui Hu, Changwei Lin, Xiaorong Li Department of Gastrointestinal Surgery, The Third Xiang Ya Hospital of Central South University, Changsha, Hunan 410013, China Purpose: Negative elongation factor complex...

Efficacy and safety of bevacizumab-based combination therapy for treatment of patients with metastatic colorectal cancer

Efficacy and safety of bevacizumab-based combination therapy for treatment of patients with metastatic colorectal cancer Ran Xu,1,2,* Chen Xu,1,* Chuntong Liu,3 Can Cui,4 Jing Zhu51Medical School of Nantong University, Jiangsu 226001, China; 2Huai’an Key Laboratory of Gastrointestinal Cancer, Jiangsu 223001, China; 3XuZhou Medical University, Jiangsu 221000, China; 4Macau...

Pathological complete response induced by neoadjuvant treatment using BRAF and MEK inhibitors in a patient with unresectable BRAF V600E-mutant malignant melanoma of the gallbladder

Pathological complete response induced by neoadjuvant treatment using BRAF and MEK inhibitors in a patient with unresectable BRAF V600E-mutant malignant melanoma of the gallbladder Zhou Yu,1 Elisa Quiroz,2 Yulei Shen,3 Ishmael A Jaiyesimi1 1Department of Hematology and Oncology, William Beaumont Hospital, Oakland University – William Beaumont School of Medicine, Royal Oak, MI...

A peptide-CpG-DNA-liposome complex vaccine targeting TM4SF5 suppresses growth of pancreatic cancer in a mouse allograft model

A peptide-CpG-DNA-liposome complex vaccine targeting TM4SF5 suppresses growth of pancreatic cancer in a mouse allograft model Sangkyu Park,1,2,* Dongbum Kim,3,* Guang Wu,3,4 Harry Jung,3 Jeong-A Park,1,2 Hyung-Joo Kwon,3,5 Younghee Lee1,2 1Department of Biochemistry, College of Natural Sciences, Chungbuk National University, Cheongju, Chungbuk 28644, Republic of Korea...

Prolyl hydroxylase domain 3 influences the radiotherapy efficacy of pancreatic cancer cells by targeting hypoxia-inducible factor-1α

Prolyl hydroxylase domain 3 influences the radiotherapy efficacy of pancreatic cancer cells by targeting hypoxia-inducible factor-1alpha Li-rui Tang,1,* Jun-xin Wu,1,* Shao-li Cai,2 Yun-xia Huang,1 Xue-qing Zhang,1 Wan-kai Fu,1 Qing-yang Zhuang,1 Jin-luan Li1 1Department of Radiation Oncology, Fujian Medical University Cancer Hospital, Fujian Cancer Hospital, Fuzhou, China; 2Key...

Near-infrared nanoparticles based on indocyanine green-conjugated albumin: a versatile platform for imaging-guided synergistic tumor chemo-phototherapy with temperature-responsive drug release

Near-infrared nanoparticles based on indocyanine green-conjugated albumin: a versatile platform for imaging-guided synergistic tumor chemo-phototherapy with temperature-responsive drug release Yuxin Ma,1 Xiaohua Liu,1 Qianli Ma,2 Yizhi Liu3 1Jinan Stomatologic Hospital, Jinan 250001, Shandong, China; 2School and Hospital of Stomatology, Shandong University, Jinan 250001, Shandong...

Vandetanib (ZD6474) induces antiangiogenesis through mTOR–HIF-1 alpha–VEGF signaling axis in breast cancer cells

Vandetanib (ZD6474) induces antiangiogenesis through mTOR-HIF-1 alpha-VEGF signaling axis in breast cancer cells Ling Li,1,* Jingkui Yu,2,* Shuhong Jiao,1 Wei Wang,1 Fen Zhang,1 Shiqing Sun1 1Department of Oncology, Affiliated Tengzhou Central People’s Hospital of Jining Medical University, Zaozhuang, Shandong, China; 2Breast Surgery Department, Affiliated Tengzhou Central People...

KIAA1199 overexpression is associated with abnormal expression of EMT markers and is a novel independent prognostic biomarker for hepatocellular carcinoma

KIAA1199 overexpression is associated with abnormal expression of EMT markers and is a novel independent prognostic biomarker for hepatocellular carcinoma Zhengchen Jiang,1,* Xiangyu Zhai,1,* Binyao Shi,1 Dan Luo,2 Bin Jin1 1Department of General Surgery, Qilu Hospital of Shandong University, Jinnan, China; 2School of Basic Medical Science, Shandong University, Jinnan, China...

The return of gemtuzumab ozogamicin: a humanized anti-CD33 monoclonal antibody–drug conjugate for the treatment of newly diagnosed acute myeloid leukemia

The return of gemtuzumab ozogamicin: a humanized anti-CD33 monoclonal antibody-drug conjugate for the treatment of newly diagnosed acute myeloid leukemia Pamela C Egan, John L Reagan Division of Hematology and Oncology, Rhode Island Hospital, The Alpert Medical School of Brown University, Providence, RI, USA Abstract: Through the years gemtuzumab ozogamicin (GO) has moved from a...

The effect of piperlongumine on endothelial and lung adenocarcinoma cells with regulated expression of profilin-1

The effect of piperlongumine on endothelial and lung adenocarcinoma cells with regulated expression of profilin-1 Maciej Gagat,1 Marta Hałas-Wiśniewska,1 Wioletta Zielińska,1 Magdalena Izdebska,1 Dariusz Grzanka,2 Alina Grzanka1 1Department of Histology and Embryology, Faculty of Medicine, Nicolaus Copernicus University in Toruń, Collegium Medicum in Bydgoszcz, Bydgoszcz, Poland...

Follicle-stimulating hormone inhibits cervical cancer via NF-κB pathway

Follicle-stimulating hormone inhibits cervical cancer via NF-kappaB pathway Xi Shi,1,* Shiwei Qiu,1,* Wei Zhuang,1,* Caiji Wang,1 Shili Zhang,1 Na Yuan,1 Fukang Yuan,2 Yuehua Qiao1 1The Institute of Audiology and Speech Science of Xuzhou Medical College, Xuzhou 221002, People’s Republic of China; 2Department of Vascular Surgery of Xuzhou Central Hospital, Xuzhou Institute of...