Canadian Respiratory Journal

https://www.hindawi.com/journals/crj/

List of Papers (Total 2,126)

Monitoring during Mechnical Ventilation

Monitoring is a continuous, or nearly continuous, evaluation of the physiological function of a patient in real time to guide management decisions, including when to make therapeutic interventions and assessment of those interventions. Pulse oximeters pass two wavelengths of light through a pulsating vascular bed and determine oxygen saturation. The accuracy of pulse oximetry is...

Smoking Inside Canadian Acute Care Hospitals

OBJECTIVE: To assess smoking policies at Canadian acute care hospitals.

Knowledge Brokering: An Innovative Model for Supporting Evidence-Informed Practice in Respiratory Care

The process of adopting research findings in the clinical setting is challenging, regardless of the area of practice. One strategy to facilitate this process is the use of knowledge brokering. Knowledge brokers (KBs) are individuals who work to bridge the gap between researchers and knowledge users. In the health care setting, KBs work closely with clinicians to facilitate...

Current Practice in the Management of Pulmonary Nodules Detected on Computed Tomography Chest Scans

Lung cancer is associated with high mortality. It can present as one or more pulmonary nodules identified on computed tomography (CT) chest scans. The National Lung Screening Trial has shown that the use of low-dose CT chest screening can reduce deaths due to lung cancer. High adherence to appropriate follow-up of positive results, including imaging or interventional approaches...

Cardiorespiratory Responses to Glittre ADL Test in Bronchiectasis: A Cross-Sectional Study

Background. Bronchiectasis is a chronic respiratory condition characterised by chronic sputum production, fatigue, and dyspnoea. These symptoms will lead to reduced exercise capacity and a reduced ability to carry out activities of daily living. Glittre ADL test is a valid and reliable test which evaluates the activities of daily living. Aim. To investigate whether the Glittre...

Cost Effectiveness of Bosentan for Pulmonary Arterial Hypertension: A Systematic Review

Objectives. Although many studies have reported on the cost-effectiveness of bosentan for treating pulmonary arterial hypertension (PAH), a systematic review of economic evaluations of bosentan is currently lacking. Objective evaluation of current pharmacoeconomic evidence can assist decision makers in determining the appropriate place in therapy of a new medication. Methods...

Airways Hyperresponsiveness and Atopy: A Comparison of Inuit and Montreal Schoolchildren

OBJECTIVE: To compare the prevalence ol exercise induced bronchial hyperresponsiveness in Inuit children with that or children in Montreal, and to identify possible genetic and environmental determinants of the differences observed.

Steroids: First Line Treatment in Pediatrics

The benefits derived from the use or inhaled steroids in pediatric asthma are reviewed in relation to the age of the patient, the delivery system and the compliance versus frequency of administration of these medications. Side effects are discussed with regard to the age or the child and the following systems: the eyes, the skin, the oropharynx, the voice, the immune system...

What Is the Role of Beta-Agonist Bronchodilators in the Day-to-Day Treatment of Chronic Asthma?

The reported links of asthma morbidity and mortality to the use of in haled beta-agonist bronchodilators are reviewed. Reports from the Saskatchewan Asthma Epidemiology Project (SAEP) suggest that it is excessive use that is linked to life-threatening asthma and that patients at highest risk can be identified by their increasing use of these medications. This is the major...

The Future of Asthma Treatment

In the past few years, significant progress has been made in the treatment of asthma with the development of bronchodilators with longer durations of action, more concentrated inhaled steroid formulations and new modes of administering antiasthma medication. Furthermore, the hey role of education in the management of asthma has been emphasized and many educational programs have...

Superiority of Spacer/Mask Topical Anesthetic Compared with Conventional Spray and Gargle Method for Fibreoptic Bronchoscopy

OBJECTIVE: To compare the safety and efficacy of a new spacer-oral nasal mask device with those of the standard needle nozzle spray method for the delivery of aerosolized lidocaine to the upper airway for pre-bronchoscopic anaesthesia in a tertiary care hospital.

Premenstrual Exacerbation of Life-Threatening Asthma: Effect of Gonadotrophin Releasing Hormone Analogue Therapy

Variability in the severity of asthma during various phases of the menstrual cycle has been frequently suspected. However, the hormonal changes that might affect mediators of bronchospasm have yet to be elucidated. The case of a 41-year-old woman suffering from longstanding asthma with life-threatening exacerbations is reported. The patient was treated with buserelin, a...

Outcome from Acute Repsiratory Distress Syndrome: Is It Really Improving?

Assessing the severity of the acute respiratory distress syndrome (ARDS) is important in determining the prognosis in any given patient and in assessing the adequacy of various forms of therapy. Mortality from ARDS has been high since the syndrome was first described almost 30 years ago. Sepsis and extrapulmonary organ failure are the major contributing factors affecting the...

Staging Lung Cancer: Current Controversies and Strategies

A consistent approach to staging is required for the rational management of lung cancer. This paper was prepared at the request of the Standards Committee of the Canadian Thoracic Society, and reviews and discusses the relative merits of the available methods of staging. Whichever methods are chosen by a particular institution, the following points must be stressed. No patient...

Airway Inflammation and Structural Changes in Airway Hyper-Responsiveness and Asthma: An Overview

Asthma treatment has moved from bronchodilator therapy to an emphasis on anti-inflammatory therapy. Airway inflammation is believed to induce airway hyper-responsiveness (AHR) through the release of mediators that increase the airway response to agonists. However, the exact contribution of airway inflammation in the physiology of airway hyper-responsiveness remains undefined...

Vocal Cord Paralysis and Respiratory Muscle Weakness: An Unusual Presentation of Chronic Polyneuropathy

A case of chronic polyneuropathy that manifested with an unusual combination of vocal cord paralysis and respiratory muscle weakness is reported. In addition, results of an exercise test carried out to assess the severity and mechanisms of exertional breathlessness in this unique condition with combined obstructive and restrictive disorders are described.

Occupational Neutrophilic Asthma

Occupational asthma is typically associated with an eosinophilic bronchitis. The case of a 41-year-old woman who developed symptoms of asthma after occupational exposure to metal working fluids is reported. The diagnosis of asthma was confirmed by an forced expiratory volume in 1 s (FEV1) of 1.7 (59% predicted), with 11% reversibility after inhaled bronchodilator and a...

Regional Distribution of Gas in the Lung

In 1966, a paper entitled "Regional distribution of gas in the lung

Number 4: Advice on Air Travel for Patients with Chronic Respiratory Conditions

The development of commercial air travel has allowed safe and convenient travel to almost all parts of the world. For patients with chronic respiratory conditions, current proactive attitudes, coupled with advances in drug therapy, oxygen delivery systems and rehabilitation programs, have resulted in many more of us being able to experience the freedom of air travel. When...

Post-Christmas Blues: A Rare Cause of Cyanosis

A patient was referred for urgent evaluation of cyanosis. Although she had symptoms and signs of an upper respiratory tract infection, she had a normal cardiorespiratory examination and normal transcutaneous oxygen saturation. Further evaluation revealed a benign cause for the cyanosis.