Current Obstetrics and Gynecology Reports

http://link.springer.com/journal/13669

List of Papers (Total 78)

Caring for Pregnant Women with Opioid Use Disorder

Purpose of ReviewThe US opioid epidemic continues historic trends of disproportionately affecting women. However, attention to the rise in neonatal opioid withdrawal syndrome (NOWS) and other types of neonatal care often overshadow the urgent need for improved and more wide-ranging maternal treatment in the peripartum period.Recent FindingsThis review aims to highlight the trends...

Natural History of Uterine Fibroids: A Radiological Perspective

Purpose of ReviewThis review aims to update our understanding of the radiological life cycle of fibroids, so that we may better counsel patients making difficult treatment decisions. Evidence for both pregnant and non-pregnant women have been considered separately.Recent FindingsRecent findings have shown that fibroids can undergo both growth and regression in non-gravid uterus...

A High-Strength, Absorbable, Antibacterial Knotless Tissue Control Device for Fascial Closure

Purpose of ReviewThis review provides an overview of the STRATAFIX™ SYMMETRIC PDS™ Plus Knotless Tissue Control Device design and performance characteristics and highlights the device’s relevance for use in gynecological procedures. Various device testing was conducted on tensile strength, fixation tab mass comparison to conventional suture knot tower, initiation stitch strength...

A New Paradigm for Uterine Fibroid Treatment: Transcervical, Intrauterine Sonography-Guided Radiofrequency Ablation of Uterine Fibroids with the Sonata System

Purpose of Review This article provides the current evidence related to transcervical radiofrequency ablation of uterine fibroids under integrated intrauterine sonography guidance (the Sonata System). Recent Findings Published data on the treatment of fibroids with the Sonata System has demonstrated significant median reductions in total (73.3%) and perfused (73.3%) uterine...

Radiofrequency Ablation of Uterine Fibroids: a Review

Laparoscopic, ultrasound-guided radiofrequency ablation (RFA) is a new, FDA-cleared uterine sparing, outpatient procedure for uterine fibroids. The procedure utilizes recent technological advancements in instrumentation and imaging, allowing surgeons to treat numerous fibroids of varying size and location in a minimally invasive fashion. Early and mid-term data from multi-center...

The Zika Virus and Pregnancy

Purpose of Review Following the recent association of Zika virus with microcephaly in Brazil, there has been a multitude of studies attempting to elucidate the relationship between Zika virus infection in pregnancy and congenital anomalies. The American Congress of Obstetricians and Gynecologists (ACOG), the U.S. Centers for Disease Control and Prevention (CDC), and the Society...

Caring for Pregnant Women with Opioid Use Disorder in the USA: Expanding and Improving Treatment

Purpose of the Review Opioid use disorder in the USA is rising at an alarming rate, particularly among women of childbearing age. Pregnant women with opioid use disorder face numerous barriers to care, including limited access to treatment, stigma, and fear of legal consequences. This review of opioid use disorder in pregnancy is designed to assist health care providers caring...

The Role of Complementary and Alternative Medicine for the Management of Fibroids and Associated Symptomatology

This article discusses the role of complementary and alternative medicine (CAM) in the management of fibroids and associated symptomatology. Since there is such a paucity of direct research related to fibroids, conditions that are implicated in the causation of uterine fibroids and symptomatology that CAM treatments may or have been shown to make a difference are also considered.

Fibroids and Infertility

The precise impact of fibroids, which are the most common benign gynaecological tumours in women, on reproductive function and infertility is unknown. The need to treat submucosal fibroids is widely accepted, but fibroids in other locations and sizes continue to present a clinical conundrum. This article examines the mechanisms by which fibroids affect implantation and fertility...

Male Hormonal Contraception: Where Are We Now?

Hormonal male contraception clinical trials began in the 1970s. The method is based on the use of exogenous testosterone alone or in combination with a progestin to suppress the endogenous production of testosterone and spermatogenesis. Studies using testosterone alone showed that the method was very effective with few adverse effects. Addition of a progestin increases the rate...

Genetics and Epigenetics of Recurrent Hydatidiform Moles: Basic Science and Genetic Counselling

Gestational trophoblastic disease (GTD) is a group of conditions that originate from the abnormal hyperproliferation of trophoblastic cells, which derive from the trophectoderm, the outer layer of the blastocyst that would normally develop into the placenta during pregnancy. GTDs encompass hydatidiform mole (HM) (complete and partial), invasive mole, gestational choriocarcinoma...

Management of Chemoresistant and Quiescent Gestational Trophoblastic Disease

Gestational trophoblastic neoplasia (GTN) is highly chemosensitive and has a high cure rate. Since the introduction of chemotherapy, reliable measurement of human chorionic gonadotropin (hCG) levels, and individualised risk-based therapy into the management of GTN, almost all low-risk and more than 80 % of high-risk GTN cases are curable. However, approximately 25 % of high-risk...

Monopolizing Our Bodies? The Myriad Supreme Court Case and Issues of Access and Justice

The actress Angelina Jolie’s disclosure that she had a double mastectomy in 2013 shed a great deal of attention on the BRCA1 and BRCA2 genes. This disclosure was made concurrently with the June 13, 2013 U.S. Supreme Court decision in the case of Association for Molecular Pathology v. Myriad Genetics. The court held unanimously that naturally occurring DNA segment was a product of...

Twin and Preterm Labor: Prediction and Treatment

Twin pregnancies are increasing. Preterm birth is a major health problem with high incidence all over the world. It is known to have a higher incidence in twin pregnancies as well as being higher in IVF/ICSI pregnancies. Prediction of preterm birth in twins through transvaginal cervical length measurement and vaginal fetal fibronectin measurement are good and well-documented...

Fetoscopic Laser Therapy for Twin-Twin Transfusion Syndrome

Ever since the first randomized, controlled trial revealed that fetoscopic laser photocoagulation achieved better outcomes than serial amnio-drainage for all stages of twin-twin transfusion syndrome (TTTS) before 26 weeks, many centers have launched their fetoscopic laser therapy program for TTTS. Initially the nonselective method of laser therapy was applied, using the dividing...

Invited Commentary: Time to Move Breast Cancer Chemoprevention to Center Stage

Breast cancer is now the most common cancer diagnosed worldwide. There is substantial evidence that 5 years of treatment with chemopreventive agents, such as tamoxifen, raloxifene, and exemestane, can reduce the incidence of hormone-positive cancers in high-risk women. Nevertheless, the uptake of these agents has been poor, even in women with atypical hyperplasia and lobular...

Fertility Preservation for Prepubertal Girls: Update and Current Challenges

With increasing rates of diagnosis of childhood cancers and the evolution of more effective treatment options resulting in prolonged life spans, fertility preservation counseling is an integral component of the discussion at the time of diagnosis of childhood cancers. The primary fertility preservation option that exists for prepubertal girls is ovarian tissue cryopreservation...

Biology of Polyspermy in IVF and its Clinical Indication

Normal fertilization involves interaction of one sperm and one egg. When the first sperm enters the egg, the egg develops blocks on the zona pellucida and egg plasma membrane (oolemma) to prevent additional sperm from entering the egg. If more than one sperm enters the oocyte cytoplasm (ooplasm), the egg becomes polyspermic. Polyspermy has not been well studied in humans. As...

Ovarian Tissue Transplantation: Current State and Research Advancement

During the past decade, babies born from cryopreservation and transplantation of ovarian tissue have emerged as a promising alternative to restore ovarian function and fertility in cancer patients. Despite successful results obtained with conventional freezing protocols to preserve ovarian tissue, attempt for whole ovary transplantation is still under-propelling in large animal...