Knowledge, attitudes, and practices of public secondary school teachers on Zika Virus Disease: A basis for the development of evidence-based Zika educational materials for schools in the Philippines
Knowledge, attitudes, and practices of public secondary school teachers on Zika Virus Disease: A basis for the development of evidence-based Zika educational materials for schools in the Philippines
Ernesto R. Gregorio 2 3
Jr.ID 0 1 2 3
John Robert C. Medina 0 1 2 3
Marian Fe Theresa C. LomboyID 2 3
Andre Dominic P. Talaga 0 2 3
Paul Michael R. HernandezID 2 3
Mitsuya Kodama 0 1 2 3
Jun Kobayashi 0 1 2 3
0 Department of Health Promotion and Education, College of Public Health, University of the Philippines Manila/SEAMEO-TROPMED Regional Center for Public Health, Hospital Administration, and Environmental and Occupational Health , Manila , Philippines , 2 Department of Environmental and Occupational Health, College of Public Health, University of the Philippines Manila/SEAMEO-TROPMED Regional Center for Public Health, Hospital Administration, and Environmental and Occupational Health , Manila , Philippines
1 Department of Global Health, Graduate School of Health Sciences, University of the Ryukyus, Nishihara City, Japan, 4 Japanese Consortium for Global School Health Research, University of the Ryukyus , Nishihara City , Japan
2 Editor: Abdallah M. Samy, Faculty of Science, Ain Shams University (ASU) , EGYPT
3 teachers of eight public secondary schools in five villages in Quezon City , Philippines. Out
The Philippines is at risk in developing a Zika Virus (ZIKV) Disease Outbreak. One of the possible interventions is health education because students are potential health advocates and influencers to their communities through the knowledge transfers from their teachers. The competency of Filipino teachers on ZIKV Disease is yet to be described. This study aimed to assess the knowledge, attitudes, and practices of public secondary school teachers on ZIKV Disease. A modified version of the Knowledge, Attitudes, and Practices Survey of the 609 respondents, 87.3% reported that their main source of information about ZIKV is tri-media, which includes television, print, and radio. Majority of the respondents mentioned that ZIKV is transmitted through a mosquito bite (80.3%). However, only half of the participants identified vector control as a preventive strategy. Moreover, only 54% admitted to have cleaned their water containers or water sources within the last week. Only a few identified mother-to-child (23%) and sexual intercourse (8%) as other means of transmission. Half (49.8%) of the respondents felt that it is possible to acquire ZIKV in their community, while 90% perceived that a private doctor (90%) or a public hospital (88%) can effectively treat the disease. Perceived stigma is high at 50%. This study showed there was good knowledge among teachers on vector transmission of ZIKV but poor knowledge on other aspects of the disease. Also, there was a low level of perceived susceptibility and severity of
Organization (WHO-PAHO) was used to assess the knowledge; attitudes; and practices of
Data Availability Statement: All relevant data are
within the manuscript and its Supporting
Funding: JK received a funding from the Okinawa
Prefecture of Japan. http://www.infection.okinawa/.
Okinawa Prefecture had no role in the study
design, data collection and analysis, decision to
publish, or preparation of the manuscript.
Competing interests: The authors have declared
that no competing interests exist.
ZIKV which can be explained by the absence of a personal encounter with a Zika patient
and the low number of cases in the Philippines. Half of the respondents said that they
cleaned the possible mosquito breeding sites within the last week, followed by those who
cleaned their water source more than a week ago (19%). None of the socio-demographic
characteristics is significantly associated with respondents? knowledge on Zika. Only income
and location of residence were found to be significantly associated with attitudes towards
Zika. These findings call for a comprehensive training program that includes development of
teaching materials for public secondary school teachers on ZIKV Disease based from this
Nowhere has the impact of globalization been more felt than in the last two decades. It has led
to a greater mobility of people and goods which, in turn, contributed to an improved global
health and development. However, this has also paved the way for efficient disease
transmission, resulting in frequent occurrence of outbreaks in the affected country. Among the
emerging diseases, Zika Virus (ZIKV) Disease, a vector-borne health problem, has recently become a
major international concern in low and middle income countries. ZIKV Disease has similar
clinical manifestations with dengue and chikungunya, which include mild fever, headaches,
conjunctivitis, maculopapular rashes, arthralgia, myalgia, lymphadenopathy, and retro-orbital
pain. It can also cause congenital abnormalities, collectively known as congenital Zika Virus
Disease (CZVD). The public concern over ZIKV Disease was compounded by its ability to be
transmitted through both sexual and mother-to-child route. The latter can cause microcephaly
among affected babies [
Zika Virus was first identified in a Ugandan forest following a yellow fever surveillance
among rhesus monkeys in 1947. The virus was later isolated from humans in Uganda and the
United Republic of Tanzania. This was followed by reports of human infections from across
Africa and Asia from 1960s to 1980s. Outbreaks had also been reported in Yap Island,
] in 2007, French Polynesia in 2013, and in the South and Central Americas in 2015
]. In September 2016, imported cases had been documented in most Asian countries.
Countries in South-East Asia and the Western Pacific Regions such as Malaysia, the Philippines,
Singapore, Thailand and Vietnam continued to report new cases of Zika from 2015 to the present
]. Recently, Zika Virus was detected in Myanmar through analysis of serum samples from
2004 to 2017 [
In 2016, the Philippines has been classified by World Health Organization (WHO) under
Category 2, which includes countries with possible endemic transmission or evidence of local
mosquito-borne Zika infection [
]. A serologic study conducted in the country in 1953
detected 19 Zika-positive samples out of 153 sera that were examined. Decades later, a
confirmed case from a prospective cohort of 267 acute febrile patients in Cebu, a province in
central Philippines, was reported in March 2012. In September 2016, a confirmed case of Zika
Virus infection was reported in Iloilo City, a city in central Philippines, and was followed by
two other patients a week later. Three weeks thereafter, cases were confirmed from the cities of
Cebu and Muntinlupa (a city in Metro Manila). The case from Cebu City was a 22-year old
primigravid of 19 weeks. The case from Muntinlupa City was initially reported in Laguna, a
province South of Metro Manila, but the detail was clarified. Two more cases were reported in
Iloilo City, and one in the municipality of Oton, Iloilo prior to the end of September. As of
2 / 19
February 2017, the Philippine Department of Health had reported 57 Zika cases including
seven cases of pregnant women. [
The presence of the Aedes mosquito in the Philippines and the number of returning
Overseas Filipino Workers (OFW) from Zika-endemic countries can pave the way for future
]. Since Zika virus can be transmitted through sexual intercourse and from mother
to fetus, another social concern that may contribute to a higher possibility of establishing an
endemic focus in the Philippines is the increasing trend of adolescent pregnancy which may
increase the risk of complications in the unborn child [
Health education on self-protection from mosquito bites, on cleanliness of the
surroundings, and on elimination of breeding sites remains to be the best way to prevent human
transmission. School-based health education can complement community health education, since
the former provides an appropriate vehicle for a more structured and integrated prevention
education program. Several studies have shown that developing students as health messengers
or change agents were effective in combatting malaria in Ghana [
] and dengue in Sri Lanka
There had been knowledge, attitudes and practices surveys done on Zika Virus among
medical doctors [
], pregnant women [
], university students [
14, 15, 16
community residents [
] in different countries but none among secondary school teachers.
Teachers can serve as reliable sources of health information that can improve the literacy of
school-based adolescents on Zika infection 
Improving the knowledge, attitudes, and practices of teachers on diseases such as Zika is
important because they can transfer these competencies to their students who can eventually
diffuse the knowledge gained to their respective families and communities [
]. The present
knowledge, attitudes, and practices of Filipino teachers on ZIKV Disease is yet to be described.
Such baseline data can serve as a basis for the development of evidence-based health education
materials and modules about Zika Virus that can be used by teachers in the schools. It can
also be used to assess the effectiveness of future school-based health education interventions
towards ZIKV Disease prevention and control in the future. Hence, this study aimed to
determine: 1) the knowledge of Philippine public secondary school teachers on ZIKV Disease, its
modes of transmission, signs and symptoms, prevention and control; 2) their attitudes towards
ZIKV Disease and its importance as a psychosocial issue; and 3) their existing health practices
related to the prevention and control of ZIKV Disease.
The study used a descriptive cross-sectional study design to assess the knowledge, attitudes
and practices of public secondary school teachers on Zika Virus Disease.
The study was done in selected public secondary schools in Quezon City (QC), which is
composed of 143 villages. The study site was purposively selected because seven of its villages were
listed among the dengue hotspot areas National Capital Region in 2015, i.e. with yellow alert
level. Clustering of at least three cases in the past four consecutive weeks placed a village into
yellow alert level [
]. Among the seven villages, villages 1, 2, 4, 5, and 6 were considered
during the first selection of study sites due to their accessibility and lower security concerns.
The schools situated in these villages were identified using the official list of public secondary
schools in QC as the sampling frame. Invitation to participate in the survey was sent to the
school heads. However, the school heads from villages 4 and 6 declined to participate for
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unknown reasons which necessitated replacement with another hotspot village. Affirmative
responses were obtained from the head of two new schools from village 3. In addition, a school
from the village 8, which was considered as a potential study site by virtue of its vicinity with
the other hotspot villages, was included upon the approval of the school head. In total, eight
schools from five villages were included in the final selection of study sites; i.e. one school each
from villages 1, 5, and 8; two from village 3; and three from village 2.
Two out of the ten schools which were invited refused to participate but these were replaced
with two new schools from the same study area.
The target participants of the study were all the teaching staffs who hold the position of a
Teacher, Master Teacher, or Head teacher in the participating schools. Through coordination
with the office of the school principal, those who are regular employees were identified and
invited to participate. There were a total of 1,184 teachers from the eight participating schools
and 625 participated which gave a response rate of 53%. Of the 625 who agreed to participate,
609 provided a complete set of data for analysis.
The study adapted and used with permission the Knowledge, Attitudes and Practices Survey
Tool on Zika Virus Disease that was developed by the World Health Organization?Pan
American Health Organization (WHO/PAHO) [
]. A group of experts reviewed the tool in
terms of content validity, clarity, and cultural sensitivity. They include a health promotion and
education expert (ERG), a medical doctor with global health expertise (JK), an expert on global
health and disaster medicine (MK), and another medical doctor with a background on
A Self-Administered Questionnaire (SAQ) was developed with four domains. The first
domain included 17 socio-demographic information of the respondents. The second domain
is composed of items gauging the respondents? knowledge on ZIKV Disease, its cause, modes
of transmission, signs and symptoms, treatment, prevention, and control. The domain is
composed of one open-ended question and 30 pre-coded questions, of which 12 can have
multiple answers. The third domain has 19 items that measures the attitudes of the
respondents towards ZIKV Disease in terms of treatment, testing, prevention and control and
stigma. A four-point Likert scale was used to determine the degree of agreement or
disagreement of the participants with the statements. Consisting of one open-ended and 19 pre-coded
questions, the last domain focused on the respondents? practices related to the prevention of
The tool was originally written in English and translated to Filipino by two, independent,
native, bilingual Filipino speakers. Then, backward translation was done independently by two
native, bilingual Filipino speakers. The research team reviewed the back-translated SAQ and
revised as deemed necessary. The final version was pre-tested among 12 teachers in a
secondary public school in Manila. A focus group discussion was conducted among the same set of
teachers for feedback regarding the clarity and cultural sensitivity of the tool.
Reliability testing was done by including all of the items collectively in the analysis. The
overall Cronbach?s ? score was 0.755. For knowledge and attitude items, the computed alpha
were 0.845 and 0.876, respectively, which are indicative of high internal consistency. The
Cronbach?s ? remains stable within the range of 0.740?0.750 during the sequential deletion of
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Data collection, management, and analysis
Proper coordination was done during data collection. An endorsement for the study was first
obtained from the Schools Division Superintendent of the Department of Education Quezon
City Division Office. Permission to conduct the survey in their respective schools was sought
from the school principals. In each school, the SAQs were delivered and distributed among the
teachers. The respondents were given one to seven days to accomplish the SAQs prior to
Gathered data were encoded using Microsoft Excel 2013 and were analysed using IBM SPSS
version 24. Only descriptive statistics was employed in describing the socio-demographic
profile of the respondents, as well as their knowledge, attitude, and practices related to ZIKV
disease. Mean and proportions were estimated for continuous and categorical variables,
respectively. For the attitude domain, the frequency of respondents who exclusively reported strongly
agree and agree were collapsed into ?Agree?. Similarly, those who responded strongly disagree
and disagree were aggregated into ?Disagree?. A score of 4 was given to a response that strongly
agrees with a positively-phrased statement and a score of 1 to a response that strongly disagrees
with such statement. The score was reversed for negatively-phrased statements.
To determine the association between the respondents? knowledge on ZIKV transmission
and the socio-demographic characteristics, two responses to the question ?How does a person
get Zika?? were purposively selected. These are the mosquito bites and sexual transmission.
Teachers can better relate with these modes of transmission and these represent the more
likely infection routes during an epidemic as compared to mother to child and through blood
transfusion. Participants who were able to correctly identify ?mosquito bite? and ?sexual
intercourse? received one unit point for each response. Hence, the maximum score is two unit
points. Percentage score was calculated by multiplying the quotient of the sum of unit score
in each item and the maximum score with 100. Upon obtaining the percentage score, each
participant was dichotomized into having adequate and inadequate knowledge. The following
statements: ?A pharmacy or local drug vendor can effectively treat a person with Zika? and ?If
somebody in my family were to get Zika, I would want it to remain private or a secret? were
purposively selected to represent negative attitudinal traits of Filipinos which contribute to poor
health-seeking behaviors e.g., self-medication and low medical and health facility consults [
]. These negative attitudes, if not addressed, could contribute to disease transmission and
potential outbreaks. Those who disagree received 2 unit point for each statement, hence the
maximum score is 4. Percentage score was calculated by multiplying the quotient of the sum of
unit score in each item and the maximum score with 100. Upon obtaining the percentage
score, each participant was classified into having favorable and unfavorable attitude. Favorable
attitude towards Zika is operationally defined as having a percentage score of greater than
50%. Socio-demographic data such as age, sex, education, religion, position in the school,
monthly household income, location of the household, distance to the nearest health center
were dichotomized and served as the exposure variables. To determine if association exists
between the socio-demographic variables and knowledge and attitude towards Zika disease, a
Pearson Chi-Square Test was done. Fisher?s Exact Test was likewise used for a variable that has
at least one cell with less than five expected counts. The level of statistical significance (?) was
set at 0.05 with 95% level of confidence.
This study has received both technical and ethics approval from the University of the
Philippines Manila, College of Public Health Technical Review Committee (UPM-CPH-TRC) and
the University of the Philippines Manila Research Ethics Board (UPMREB), respectively.
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There were a total of 609 teachers who agreed to participate in the study. The highest
proportion of respondents (25.8%) came from School E. Table 1 shows the number and proportion of
respondents per school are distributed is as follows:
Table 2 shows that the age of the respondents range from 20 to 64 years old with a mean of
38.6 years old. The highest proportion (39.6%) belongs to the 30 to 39 age group. There were
more female respondents (68.5%) than males.
The highest proportion (31.2%) had been serving as a teacher for less than a year to 5 years,
this was followed by 23% who had been working as a teacher from 5 to 9 years.
A majority (66.7%) of the respondents professed to be Catholics while the rest are
non-Catholics. Two-thirds (65.6%) had a college degree while the rest had completed
either a master?s or a doctorate degree. More than a fifth of the respondents (22.3% to
25.6%) taught Grades 7 to 9 pupils. Around 14% to 15% taught Math, Science and MAPEH
(Music, Arts, Physical Education and Health). Much smaller proportions taught other
subjects like TLE (Technology and Livelihood Education), English, Social Studies, and Values
A little more than 60% of the respondents said they have at least a woman of reproductive
age group living in their households, but only 5% had a pregnant woman in the same
household at the time of interview. A little over a third (34%) had a monthly family income that
ranged from PhP 20, 000 to 29, 000 (400 to 580 USD).
Knowledge on the sources of information
Almost everybody claimed to have heard of Zika Virus Disease and a quarter of the
respondents said that they heard about Zika as early as 2014.
Table 3 shows that tri-media/triple media which includes TV, radio, and print (87.3%), was
the most frequent source of information about Zika Virus. This was followed by social media
(28.1%) and to a lesser extent by interpersonal communication channels like family, friends,
and health workers.
Knowledge on the modes of transmission of ZIKV Disease
A very high proportion (80.3%) mentioned that Zika Virus Disease is transmitted through a
mosquito bite. This was followed by, to a lesser extent, mother to child transmission, through
blood transfusion, and from a dirty environment. It is noteworthy that 12.3% did not know
how the disease is transmitted and 8% who mentioned coughing and sneezing as a mode of
transmission (Table 4).
Knowledge on signs and symptoms of ZIKV Disease
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identified other signs and symptoms of the said disease. It is noteworthy that 28% admitted
not knowing the signs and symptoms of Zika Virus Disease.
Knowledge on preventive measures against ZIKV Disease
The respondents were asked about their knowledge on the preventive measures against Zika
Virus Disease. The responses were logically grouped into three generic categories: 1)
environmental management and/or vector control measures; 2) use of self-protection; and 3) other
beliefs or misconceptions. Table 6 reveals that 55.7% and 54.5% of the respondents identified
cleaning/scrubbing of storage containers and house environment as preventive measures,
respectively. Also, 50.4% identified use of mosquito repellants or sprays as another preventive
measure. Self- protection measures were also mentioned to a much lesser extent. It is worth to
note that there were some who had misconceptions about Zika Virus Disease preventive
In terms of their knowledge on the possible complications of ZVD, the respondents were
asked about their understanding of microcephaly (Table 7). Thirty percent (30%) said that it is
a condition where the brain becomes smaller in size. A majority of the respondents (62%)
admitted that they did not know what microcephaly was.
Respondents? perceptions of their susceptibility and severity of Zika Virus
The respondents were likewise asked about their perceptions related to their susceptibility to
and the severity of Zika Virus Disease in their community. Table 8 shows that 61% said that it
is possible for them to acquire the disease, and that the virus is deadly or can cause death
(55%). Nearly half (43.3%) of the respondents claimed that their risks of getting Zika Virus
Disease in the next six months ranges from moderate to high. Only 49.8% mentioned that the
virus can cause disability to newborns.
Respondents? attitudes towards ZIKV Disease
The respondents? attitudes towards Zika Virus Disease were also assessed using a four-point
Likert Scale. Table 9 reveals that more than 88% agreed that a private and a public doctor can
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9 / 19
effectively treat a person infected with Zika virus. Also, more than two-thirds disagreed with
statements that a pharmacy or local drug vendor, and local healers can effectively treat Zika. A
high 80.1% agreed with the belief that all pregnant women should be tested for Zika. Even a
higher proportion (89.6%) agreed that they would consider vaccination against Zika, if it is
available and 89.5% believe that a vaccine can prevent the spread of Zika. However, there was
an ambivalence among the respondents about their attitudes towards the use of artificial
contraceptive methods to prevent pregnancy and Zika Virus Disease. Majority (72%) of the
respondents disagreed with the use of abstinence and non-use of modern family planning
methods to prevent pregnancy and Zika. Only half agreed with the statement that women
should use condom or have her partner use a condom in all sexual encounters to avoid Zika.
The respondents were also divided as far as statements related to stigma and discrimination
related to Zika were concerned.
Respondents? practices related to cleaning/scrubbing water sources/
The respondents were asked as to when was the last time they cleaned or scrubbed their water
source which could serve as a breeding for mosquito vectors (Table 10). Half of them (54%)
said within the last week, followed by those who cleaned their water source more than a week
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11 / 19
a Positive attitude?disagreed with 2 negatively-phrased attitude statement toward Zika
b Fisher?s exact test; for analysis of small numbers (at least one cell containing < 5 counts)
Zika virus by mosquito and sex. However, statistical association using Pearson?s Chi-square
test did not reach statistical significance.
Table 12 shows that females, those with bachelor?s degree only, non-Catholics, with above P
30,000 monthly family income, residing in urban areas, living in close proximity to a health
center, and teaching health-related subjects appear to have a more positive attitude toward
Zika. However, only income and location of residence were found to be significantly
associated with a positive attitude toward Zika as indicated with p?value which is equal to 0.05 or
Since 2012, the Philippines has reported only a few cases of Zika Virus Disease but this
situation should not lead to complacency among the local health authorities. With the increase in
tourist arrivals and returning Overseas Filipino Workers (OFWs) who may come from
endemic areas, and the changing ecology that favors mosquito breeding, the probability of
ZIKV outbreaks is always present. Considering the unavailability of vaccine against ZIKV
disease, health promotion remains to be the most cost-effective strategy in reducing mosquito
vector population density and human-vector contact, thereby reducing the risk of ZIKV
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transmission. This study was the first in the Philippines that aimed at determining the
knowledge, attitudes, and practices of public secondary school teachers related to Zika Virus Disease.
The findings can serve as a basis for the development and evaluation of health education
interventions in the future. Through this, the role of teachers as the primary and credible source of
information of students on health topics can be optimized.
A high level of awareness on ZIKV was found among secondary school teachers as
indicated by their self-report that almost everyone has heard about the disease. This can be
attributed to the attention given to Zika by local news networks following the reports of outbreaks
in South America. The finding is consistent with other studies which found a similarly high
level of awareness (77% to 91%) on Zika among different population groups [
13, 14, 18, 19
The reported high level of awareness is corroborated by the findings that tri-media?TV,
radio, and print, (87%) was the most frequent source of information about Zika [
13, 18, 19
This level of awareness was more or less consistent across various population groups (medical
residents, women, pregnant women and immigrants) who participated in previous studies.
Despite the high level of awareness, several participants in this study still had some
misconceptions about ZIKV disease such as transmission through coughing and sneezing, drinking of
dirty water, and bathing in polluted waters. Despite its widespread popularity and use vis-?-vis
the relatively young mean age of the study respondents, only 28% of the participants identified
social media as their source of information on ZIKV. This is lower compared to the 43.7%
among the study respondents in Qatar  but higher among pregnant women respondents
in Brunei Darussalam [
]. This may imply that information related to ZIKV was either not
adequately circulated in the social media or the respondents was not able to access this
information. A systematic review in 2013 showed that social media increases accessibility and
widens access to health information. Social media can be an important platform for disseminating
health information if properly used and monitored [
A high proportion (80%) of respondents knew that Zika can be transmitted through
mosquito bites, which may a indicate good knowledge on this particular mode of transmission.
This can be attributed to high level of awareness of the respondents on Zika Virus Disease
mode of transmission as influenced by the tri-media (TV, radio and print). Other studies
corroborated such finding [
15, 19, 28
]. One study showed that only around 58% of their
participants mentioned that Zika was transmitted by any mosquito bite, however, the same study
also mentioned that nearly 20% said that the virus is transmitted through Aedes aegypti bite
]. This study was not able to combine all the responses related to transmission by
mosquitoes which, when combined, could have reached 78%. A related study in China used two
methods of data collection, one was through internet survey which had a very high proportion of
respondents (95.2%) who knew about ZIKV transmission via mosquitoes while those recruited
through paper-based interview only had 67.3% [
]. Those who responded through the online
survey had a much higher level of health literacy because they were much younger and had a
higher level of education. It is also possible that respondents could have checked on-line
references during the survey.
Only 8% of the respondents identified sexual intercourse as a mode of transmission of
ZIKV compared to 34.6% to 59% of respondents in other studies [
15, 16, 19, 30
] but consistent
with a study finding among Ecuadorian adults . This is supported by the findings where
only 10% of the respondents said that condom use and abstinence were measures which could
prevent ZIKV transmission. Moreover, less than half of the respondents agreed with attitude
statements such us women should use condoms or have her partner use a condom in all sexual
encounters to avoid Zika (44.3%) and that, in times where there is active viral transmission,
women should avoid getting pregnant because of Zika (49%) [
]. These findings are
worrisome because this poor knowledge reinforced by a negative attitude could lead to an
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undesirable practice which might put women and their future children at risk for ZIKV disease
and its complications. These findings may be explained by the fact that ZIKV shares the same
mosquito vector as that of dengue. Since the media reports almost always reported the two
vector-borne diseases together, there is the possibility that the teachers recalled the transmission
through mosquito bite more often than through sexual intercourse. This poor knowledge
which may increase the respondents? susceptibility to ZIKV can be compounded by the
number of returning Filipino overseas workers, e.g. seafarers, who might come from areas where
there is local transmission of the virus [
While dengue has already been integrated in the curriculum, topics on ZIKV is not yet
part of secondary school subjects due to lack of teachers? training, low confidence in teaching
the topic, and the unavailability of teaching-learning resources which they can use in the
Only 23% of the respondents knew that the Zika virus is transmitted from mother to child.
Such finding is very low considering the respondents? high level of awareness and knowledge
that Zika Virus is transmissible through mosquito bite. The possible explanation is that Zika
became more commonly known as a vector-borne disease rather a disease transmitted through
the perinatal route. It was only recently that people learned about the possibility of mother to
child transmission. In other studies, only 35.0% to 56.8% of the respondents knew that Zika
Virus can be transmitted from mother to child [
13, 15, 18
]. Nevertheless, the low proportion
of response in the present study is still higher compared with the 14% found by
Aidoo-Frimpong, et. al., among the general Ecuadorian population [
]. This may be attributed to the
higher educational attainment of teachers, i.e. at least college graduate, who participated in this
There were studies which found a much higher proportion of respondents who knew the
possibility of a mother to child transmission. In the study of Borges, et. al., they found out that
almost every respondent who had ever heard about Zika was aware of the relationship of the
virus with congenital syndrome. This study was related to Zika outbreaks in Brazil which had
infected more than 200,000 people and generated 2,753 cases of confirmed congenital
syndrome. The magnitude of the problem in Brazil could have contributed to this high level of
knowledge on mother to child transmission. Moreover, Borges? respondents were recruited
from pregnant and non- pregnant women who had scheduled medical and nursing
consultations at the health facilities and would have probably received more information about Zika
compared to other population groups [
]. Arief et. al observed that more than 80% of their
survey respondents said that pregnant women are at high risk for Zika Virus attesting to their
high level of knowledge of the relationship between Zika and pregnancy [
]. Mouchtouri et.
al found that only 38% and 47% of their respondents said that women who are pregnant are at
risk of miscarriage and having a child with microcephaly should they be infected by Zika
Virus, respectively [
Knowledge on signs and symptoms is important in the early recognition and prompt
referral of cases of Zika to the health facilities. A majority of the participants had mentioned fever
(65%), followed by headache (38.6%), joint pain (29%), rashes (14.4%) and conjunctivitis
(8.2%). A quarter (28%) of the respondents did not know about the signs and symptoms Zika,
which is alarming because this could delay diagnosis and prompt treatment, and could
contribute to the spread of the virus. Poor knowledge on the recognition of signs and symptoms
maybe be due to the content of some health communication materials that focuses on the
modes of transmission, prevention, and control but less on clinical signs and symptoms of
ZIKV Disease. These findings did not vary much with those found by Samuel in their study
among immigrants in New York City [
]. It was difficult to compare the signs and symptoms
reported in other studies because of varying ways of measuring and reporting knowledge of
14 / 19
the signs and symptoms of ZVD. Arief et. al reported that 73.8% of their respondents knew
that joint pain, fever, conjunctivitis, and skin rash as signs and symptoms of ZIKV [
et. al reported 71% and 46% of their respondents mentioned fever and skin rash as signs of
ZIKV disease respectively [
A very high proportion of respondents knew that the virus is transmitted through mosquito
bites. However, only half of the participants identified vector control as a preventive measure.
This is an area that needs to be strengthened to prevent ZIKV disease outbreaks. With the
absence of an effective cure and vaccine against ZIKV, health education, as well as
environmental control measures, remains to be the main strategy as far as prevention and control
program is concerned. This result was better compared to the findings of a study done among
Colombian respondents, in which only 30% identified elimination of breeding sites and the
use of mosquito repellants as important preventive measures [
Only 30% of the respondents in this study were able to describe microcephaly. A high
proportion (62%) did not know what microcephaly is. The same was noted in another study, in
which only half of their respondents said that ZIKV can cause disability to newborns, which
could be referring to microcephaly. The high proportion of respondents who admitted not
knowing what microcephaly is or that Zika Virus is not associated with microcephaly can lead
people to practice risky behaviors because they did not know that having a small brain is a
complication of ZIKV infection. This finding is similar with what Plaster et. al found out in
their study among university students in the USA [
]. On the other hand, another study
found out a very high proportion (95%) of community members in the USA knew the clear
link between Zika Virus and microcephaly [
Among the respondents, 60% and 55% agreed with the statements such as ?they can acquire
the Zika Virus Disease? and ?ZIKV is deadly and can cause death, respectively. Half (49.8%) of
the respondents felt that there is a possibility to acquire the ZIKV in their community. This
finding is an indication of a moderate level of perceived susceptibility and severity of ZIKV
among the teachers probably because: 1) they have not encountered a case of ZIKV infection
in person, and 2) they know that the number of ZIKV cases in the Philippines is still low.
Hence, their perceived level of susceptibility to ZIKV disease is at a moderate level. This is
supported by a study done among residents of Selangor, Malaysia where only half felt that their
country is at high risk for spread of ZIKV and 33% who had ever thought they could get the
]. Nearly half (47.0%) of respondents in a study in China and 47.5% in Ecuador were
worried about contracting Zika and half of the adult respondents in an Ecuadorian study felt
at risk to contracting ZIKV [
]. This level of perceived susceptibility is much higher
compared to those found by other studies in the US , Ecuador [
], and Malaysia [
A very high proportion of participants (92%) believed that Zika is an important issue in
their community and 90% perceived that a private doctor and a public hospital can effectively
treat a person with Zika. This finding reveals that the participants recognize the importance
and threat caused by ZIKV and positive health beliefs related to Zika treatment which can
influence their positive health seeking behaviors.
The respondents? low level of perceived susceptibility to ZIKV aligns well with their poor
preventive behaviors. Only half admitted to have cleaned their water containers or water
sources within the last week and that 16% of the respondents did not know or provided no
response to this important practice of removing potential mosquito breeding sites [
]. In the
absence of effective drugs and vaccine against Zika, regular cleaning of water containers to
prevent breeding of mosquito vector is critical in preventing disease outbreaks. This practice of
cleaning water containers is much lower compared to a community in Washington, USA
whose residents are more aware and have a better Zika-preventive practice [
]. This finding
15 / 19
is worrisome since open water containers and stagnant water sources are potential mosquito
breeding sites which can give rise to vector-borne epidemics such as ZVD.
This study found that respondents who are 39 years old and older, males, with bachelor?s
degree only, non-Catholics, with above P 30,000 monthly family income, residing in urban
areas, living in close proximity to a health center, teaching health-related subjects seem to be a
little more knowledgeable about transmission of Zika virus through mosquito and sex.
However, statistical association using Pearson?s Chi-square test did not reach statistical significance.
Other studies found that knowledge on Zika transmission was not associated with social
] but was associated with residence (urban/rural) . Others have reported
statistically significant association of general knowledge on Zika with older respondents [
]. The present study shows that respondents who had attained a bachelor?s degree were
found to have a better knowledge on Zika compared to those who had at least postgraduate
units . While this appears to be counter-intuitive, however, it could be due to the fact that
those with bachelor?s degree belong to a younger subset of population whose access to social
media with health-related information is greater [
]. Other studies confirmed the
significant association of education and knowledge [
19, 26, 27, 33, 34
]. Mixed results have been
found between knowledge on Zika and sex [
]. Residing in urban areas and proximity to
health centers could be associated with knowledge about Zika as these imply better access to
health-related information. However, due to the low number of participants with sufficient
knowledge on Zika transmission, the association did not reach statistical significance.
This study also found that family income and location of residence were statistically
associated with having a positive attitude towards the disease. Association of monthly family income
with attitude towards ZVD mean that people with higher socioeconomic status have better
access to health services and information sources about Zika, and therefore have a higher
health literacy [
]. The association between urban residence and having a positive attitude
toward Zika could be still be related to a greater exposure to health messages and access to
health services in urban areas. This finding is consistent with a study in Selangor, Malaysia
where residents living in rural areas had a favorable attitude towards Zika . Some studies
did not include location of residence as part of the sociodemographic profile [
14, 15, 26, 28
while others use a different measure for attitude [
The lack of statistically significant association between the socio-demographic
characteristics and knowledge on Zika transmission as well as attitude towards Zika (except for income
and type of residence) should be viewed with reference the low number of participants with
sufficient knowledge and attitude on Zika transmission that reduced the power of the test to
detect statistically significant associations.
Teachers who participated in this study had a good level of knowledge on the transmission of
ZIKV through mosquito bite but poor knowledge about mother to child transmission,
transmissions through sexual intercourse and breastfeeding, complications of the infection, and
preventive practices. Their perception towards susceptibility to and severity of ZIKV is low
which could probably be due to the absence of an actual encounter with a Zika patient and the
low number of reported cases in the Philippines. Attitudes towards the effectiveness of doctors
in treating Zika is high but some still believe that local healers can effectively treat Zika.
Respondents? knowledge and attitudes toward prevention of sexual transmission is low. There
was ambivalence in terms of attitude towards social stigma related to ZIKV. Given that the
ingredients of a possible Zika epidemic is present in the Philippines, the education materials
that can be developed for teachers should include topics that will improve their perceptions
16 / 19
towards their susceptibility and severity of ZIKV, their knowledge on sexual mode of
transmission, how to prevent the virus from being transmitted through sexual intercourse or mother to
child, and the practice of regularly cleaning open water containers which can serve as potential
mosquito breeding sites. Correcting misconceptions such as transmission through coughing
and sneezing, drinking of dirty water and bathing in polluted water should also be included in
the educational materials to prevent spreading these misconceptions to learners. Learners look
at their teachers as their role models and a reliable source of knowledge, hence, the latter?s
competency on Zika should be no less than satisfactory. Social media can also be used as a
supplementary channel for in-service training for teachers since the results imply that those who
only had bachelor?s degree appear to be younger respondents access this type of media for
health-related information. This study provided baseline data from which the effects of future
curricular interventions on teachers? knowledge, attitudes and practices related to Zika virus
can be compared against.
Income and location of residence were found to be significantly associated with attitude
towards Zika virus and ZVD. These highlight the role of a social determinant, i.e. income, in
influencing health-related attitudes and overall health.
The above results and conclusion should be taken in the light of the study?s limitations.
Despite the explanation of the potential contribution of the study to teachers, the teachers?
response rate was reported at 53%. Self-selection bias might have affected the results of the study
since it was possible that study participants might have a different set of characteristics than
nonstudy participants. The use of self-administered questionnaire might also have introduced some
information bias but this was minimized by anonymizing the tool and adding response options.
The authors would like to thank the administrators and the teachers of the schools who
participated in this study. Also to Dr. Daisuke Nonaka and Prof. Maylin C. Palatino for their advice
on the statistical analysis of data on association.
Conceptualization: Ernesto R. Gregorio, Jr., John Robert C. Medina, Jun Kobayashi.
Data curation: Ernesto R. Gregorio, Jr., John Robert C. Medina, Marian Fe Theresa C.
Lomboy, Andre Dominic P. Talaga, Paul Michael R. Hernandez.
Formal analysis: Ernesto R. Gregorio, Jr., John Robert C. Medina, Marian Fe Theresa C.
Lomboy, Paul Michael R. Hernandez, Mitsuya Kodama.
Funding acquisition: Jun Kobayashi.
Investigation: Ernesto R. Gregorio, Jr., Andre Dominic P. Talaga, Mitsuya Kodama, Jun
Methodology: Ernesto R. Gregorio, Jr., Marian Fe Theresa C. Lomboy, Jun Kobayashi.
Project administration: Ernesto R. Gregorio, Jr., Andre Dominic P. Talaga, Mitsuya Kodama,
17 / 19
Resources: Mitsuya Kodama, Jun Kobayashi.
Software: Mitsuya Kodama, Jun Kobayashi.
Supervision: Ernesto R. Gregorio, Jr., Mitsuya Kodama.
Validation: Ernesto R. Gregorio, Jr., Marian Fe Theresa C. Lomboy, Paul Michael R.
Hernandez, Mitsuya Kodama, Jun Kobayashi.
Writing ? original draft: Ernesto R. Gregorio, Jr., John Robert C. Medina, Jun Kobayashi.
Writing ? review & editing: Ernesto R. Gregorio, Jr., John Robert C. Medina, Marian Fe
Theresa C. Lomboy, Andre Dominic P. Talaga, Paul Michael R. Hernandez, Mitsuya Kodama,
18 / 19
1. World Health Organization [WHO]/PAHO. Zika strategic response plan quarterly update . 2016 . http:// www.who.int/iris/handle/10665/250626.
2. Duffy MR , Chen TH , Hancock WT , Powers AM , Kool JL , Lanciotti RS , et al. Zika virus outbreak on Yap Island, federated states of Micronesia. New England Journal of Medicine . 2009 Jun 11 ; 360 ( 24 ): 2536 - 43 . https://doi.org/10.1056/NEJMoa0805715 PMID: 19516034
3. Cao-Lormeau VM , Roche C , Teissier A , Robin E , Berry AL , Mallet HP , et al. Zika virus, French Polynesia, South Pacific, 2013 . Emerging infectious diseases. 2014 Jun; 20 ( 6 ): 1085 - 86 . https://dx.doi. org/10. 3201%2Feid2006.140138 PMID: 24856001
4. World Health Organization [WHO]/PAHO. Zika strategic response plan. 2016 . http://www.who.int.
5. Tun MM , Kyaw AK , Hmone SW , Inoue S , Buerano CC , Soe AM , et al. Detection of Zika virus infection in Myanmar . The American Journal of Tropical Medicine and Hygiene . 2018 Mar; 98 ( 3 ): 868 - 71 . https:// doi.org/10.4269/ajtmh.17-0708 PMID: 29363460
6. ABS CBN News. 57 Zika cases in PH; DOH verifying microcephaly case. Febraury 3 , 2017 . [Accessed 8 October , 2017 ]. http://news.abs-cbn.com/news/02/03/17/57-zika -cases-in-ph-doh-verifyingmicrocephaly-case.
7. Massad E , Tan SH , Khan K , Wilder-Smith A. Estimated Zika virus importations to Europe by travellers from Brazil . Global Health Action. 2016 Dec 1 ; 9 ( 1 ): 31669 . https://dx.doi.org/10.3402% 2Fgha . v9 . 31669
8. Philippine Statistics Authority ( 2016 ). 2015 Full Year Official Poverty Statistics of the Philippines . https:// psa.gov. ph/sites/default/files/2015%20Full%20Year%20Official%20Poverty%20Statistics%20of% 20the%20Philippines%20Publication.pdf
9. Ayi I , Nonaka D , Adjovu JK , Hanafusa S , Jimba M , Bosompem KM , et al. School-based participatory health education for malaria control in Ghana: engaging children as health messengers . Malaria Journal . 2010 Dec; 9 ( 1 ): 98 . https://dx.doi.org/10.1186% 2F1475 - 2875 -9-98
10. Jayawardene WP , Lohrmann DK , Youssefagha AH , Nilwala DC . Prevention of dengue fever: An exploratory school-community intervention involving students empowered as change agents . Journal of School Health . 2011 Sep; 81 ( 9 ): 566 - 73 . https://doi.org/10.1111/j.1746- 1561 . 2011 . 00628 . x PMID : 21831070
11. Harapan H , Alleta A , Anwar S , Setiawan AM , Maulana R , Wahyuniati N , et al. Attitudes towards Zika virus infection among medical doctors in Aceh province, Indonesia . Journal of infection and public health . 2018 Jan 1 ; 11 ( 1 ): 99 - 104 . https://doi.org/10.1016/j.jiph. 2017 . 06 .013 PMID: 28736184
12. Borges AL , Moreau C , Burke A , dos Santos OA , Chofakian CB . Women's reproductive health knowledge, attitudes and practices in relation to the Zika virus outbreak in northeast Brazil . PloS one . 2018 Jan 3 ; 13 ( 1 ):e0190024. https://doi.org/10.1371/journal.pone. 0190024 PMID: 29298358
13. Mouchtouri VA , Papagiannis D , Katsioulis A , Rachiotis G , Dafopoulos K , Hadjichristodoulou C . Knowledge, attitudes, and practices about the prevention of mosquito bites and Zika virus disease in pregnant women in Greece . International journal of environmental research and public health . 2017 Mar 31 ; 14 ( 4 ): 367 .
14. Painter JE , Plaster AN , Tjersland DH , Jacobsen KH . Zika virus knowledge, attitudes, and vaccine interest among university students . Vaccine. 2017 Feb 7 ; 35 ( 6 ): 960 - 5 . https://doi.org/10.1016/j.vaccine. 2016 . 12 .050 PMID: 28069360
15. Plaster AN , Painter JE , Tjersland DH , Jacobsen KH . University students' knowledge, attitudes, and sources of information about Zika virus . Journal of community health . 2018 Jan 9 : 1 - 9 .
16. Katler Q , Godiwala P , Macri C , Pineles B , Simon G , Chang A , et. al. Evolution of Knowledge , Awareness, and Practices regarding Zika Virus from 2016 to 2017 . Infectious diseases in obstetrics and gynecology . 2017 Nov 20 ; 2017 : 6350602. https://doi.org/10.1155/ 2017 /6350602 PMID: 29348707
17. Casapulla SL , Aidoo-Frimpong G , Basta TB , Grijalva MJ . Zika virus knowledge and attitudes in Ecuador. AIMS public health . 2018 ; 5 ( 1 ): 49 . https://doi.org/10.3934/publichealth. 2018 . 1 .49 PMID: 30083569
18. Cheema S , Maisonneuve P , Weber I , Fernandez-Luque L , Abraham A , Alrouh H , et. al. Knowledge and perceptions about Zika virus in a Middle East country . BMC infectious diseases . 2017 Dec; 17 ( 1 ): 524 . https://doi.org/10.1186/s12879-017 -2603-6 PMID: 28747174
19. Arief M , Hassali MA , Saleem F , Khan MU , Ahmad A , Bhagavathulha AS , et al. A cross-sectional survey on the knowledge and attitudes towards Zika virus and its prevention among residents of Selangor, Malaysia . J Pharm Pract Community Med . 2017 ; 3 : 81 - 89 .
20. Hattie J . Teachers make a difference: What is the research evidence? Paper presented at the Building Teacher Quality: What does the research tell us ACER Research Conference , Melbourne, Australia. ( 2003 ) Retrieved from http://research.acer.edu.au/research_conference_2003/4/
21. Bonalos P. 80 barangays now on yellow alert vs . dengue. CNN Philippines . 2016 Aug 17. [cited 2016 Nov 10 ] http://cnnphilippines.com/news/2016/08/16/80-barangays -dengue-yellow-alert .html
22. Department of Health. Disease Surveillance: 2015 Dengue Morbidity 31 . Accessed from http://www. doh.gov.ph/statistics
23. World Health Organization. Knowledge, Attitudes, and Practices Surveys Zika Virus Disease and Potential Complications: Resource Packs . 2016 . Geneva, Switzerland: WHO Press.
24. Philippine Statistics Authority ( PSA) and ICF. 2018 . Key Findings from the Philippines National Demographic and Health Survey 2017 . Quezon City, Philippines, and Rockville , Maryland, USA: PSA and ICF . https://www.dhsprogram.com/pubs/pdf/SR253/SR253.pdf
25. Bulario JS , Cruz IP , Pilapil MC , Gutierrez MM . Factors Associated with Parental Self-medication of Antibiotics in Health Centers of Manila . 4th International Research Conference on Higher Education, KnE Social Sciences . 2018 ; 891 - 910 .
26. Chaw LL , Tuah NAA , Wong JYY , Naing L. K. Knowledge , attitudes, and practice survey on Zika virus infection among pregnant women in Brunei Darussalam . Asian Pac J Trop Med . 2018 ; 638 - 644 .
27. Moorhead SA , Hazlett DE , Harrison L , Carroll JK , Irwin A , Hoving C. A New Dimension of Health Care: Systematic Review of the Uses, Benefits, and Limitations of Social Media for Health Communication . J Med Internet Res 2013 ; 15 ( 4 ):e85 https://doi.org/10.2196/jmir.1933 PMID: 23615206
28. Jaramillo Ram??rez GI, A?lvarez LS. Knowledge, attitudes and practices regarding Dengue, Chikungunya, and Zika and their vector Aedes Aegypti in Villavicencio, Colombia . The Open Public Health Journal. 2017 Jun 21 ; 10 ( 1 ).
29. Huang Y , Xu S , Wang L , Zhao Y , Liu H , Yao D , et al. Knowledge, attitudes, and practices regarding Zika: paper-and internet-based survey in Zhejiang, China . JMIR Public Health and Surveillance . 2017 Oct; 3 ( 4 ).
30. Samuel G , DiBartolo-Cordovano R , Taj I , Merriam A , Lopez JM , Torres C , et al. A survey of the knowledge, attitudes and practices on Zika virus in new York City . BMC Public Health. 2018 Dec; 18 ( 1 ): 98 . https://doi.org/10.1186/s12889-017 -4991-3 PMID: 29291723
31. Aidoo-Frimpong G , Basta T , Gomez G , Casapulla S , Grijalva M. Zika virus knowledge and attitudes among Ecuadorian adults . Annals of Global Health. 2017 Apr 7 ; 83 ( 1 ): 59 - 60 .
32. Mwamwenda TS , Kariuki PW . University of Nairobis' Students' Level of HIV/AIDS Knowledge . Mediterranean Journal of Social Sciences . 5 ( 27 ): 500 - 505 .
33. Lohrmann C , Valimaki M , Suominen T , Muinonen U , Dassen T , Peate I ( 2000 ). German nursing students' knowledge of and attitudes to HIV and AIDS:two decades after the first AIDS case . Journal of Advanced Nursing . 31 ( 3 ): 696 - 703 . PMID: 10718890
34. Heitzinger K , Thoroughman DA , Porter KA . Knowledge, attitudes, and practices of women of childbearing age testing negative for Zika Virus in Kentucky, 2016 . Preventive Medicine Reports. 2018 ; 20 - 23 .
35. Castro M , Sanchez L , Perez D , Sebrango C. Skedy Z , Van der Stuyft P. The Relationship between Economic Status, Knowledge of Dengue, Risk Perceptions and Practices . PloS ONE . 2013 ; 8 ( 12 ).
36. Whiteman A , Mejia A , Hernandez I , Loaiza R . Socioeconomic and demographic predictors of resident knowledge, attitude, and practice regarding arthropod-borne viruses in Panama . BMC Public Health . 2018 ; 18 : 1261 . https://doi.org/10.1186/s12889-018 -6172-4 PMID: 30428861