Correction to: High-yield production of l-serine from glycerol by engineered Escherichia coli

Journal of Industrial Microbiology & Biotechnology, Apr 2019

Xiaomei Zhang, Dong Zhang, Jiafen Zhu, Wang Liu, Guoqiang Xu, Xiaojuan Zhang, Jinsong Shi, Zhenghong Xu

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Correction to: High-yield production of l-serine from glycerol by engineered Escherichia coli

Journal of Industrial Microbiology & Biotechnology pp 1–3 | Cite as Correction to: High-yield production of l-serine from glycerol by engineered Escherichia coli AuthorsAuthors and affiliations Xiaomei ZhangDong ZhangJiafen ZhuWang LiuGuoqiang XuXiaojuan ZhangJinsong ShiZhenghong Xu Correction First Online: 26 April 2019 121 Downloads The original article can be found online at  https://doi.org/10.1007/s10295-018-2113-6. Correction to: Journal of Industrial Microbiology & Biotechnology (2019) 46:221–230  https://doi.org/10.1007/s10295-018-2113-6 Unfortunately, the order of the Figs. 1–4 has been positioned wrongly in the print published article. Following are the corrections: Fig. 1 of this article should be placed in the position of Fig. 2, Fig. 2 should be placed in the position of Fig. 3, Fig. 3 should be placed in the position of Fig. 4, and Fig. 4 should be placed in the position of Fig. 1. The correct figures (Figs. 1, 2, 3, 4) are given below. Open image in new window Fig. 1 l-serine biosynthesis pathways from glycerol in E. coli. Genes and enzymes: glycerol facilitator (glpF); glycerol kinase (glpK); glycerol 3-phosphate dehydrogenase (glpD); 3-phosphoglycerate dehydrogenase (serA); phosphoserine aminotransferase (serC); phosphoserine phosphatase (serB); cysteine/acetyl serine transporter (eamA); serine hydroxymethyltransferase (glyA); l-serine deaminases (sdaA, sdaB, and tdcG). Intermediates: dihydroxyacetone phosphate (DHAP); phosphoenolpyruvate (PEP); tricarboxylic acid cycle (TCA). Highlighted arrows indicate pathways in which genes were upregulated by overexpression eamA. Red crosses on solid lines ( Open image in new window ) indicate genes that were deleted. Crosses on dashed lines ( Open image in new window ) indicate the removal of feedback inhibition (color figure online) Open image in new window Fig. 2 Comparison of glycerol consumption, cell growth, and l-serine production of strains W3110, G, GA and GAA. a Profiles of residual glycerol and cell density with strains W3110, G, and GA. Squares represent W3110, circles represent G, triangles represent GA, open symbols represent OD600, closed symbols represent residual glycerol. b Profiles of glycerol consumption, cell growth and l-serine production in GAA. Squares represent residual glycerol, circles represent cell growth, triangles represent l-serine. Values denote the average of three independent experiments, and error bars indicate standard deviation Open image in new window Fig. 3 Time course of l-serine production in the 4W strain during batch fermentation. Squares represent residual glycerol, circles represent cell growth, triangles represent l-serine. Values denote the average of three independent experiments, and error bars indicate standard deviation Open image in new window Fig. 4 Comparison of glycerol consumption, cell growth and l-serine production in strains 4W-glpD–glpK and 4WA. a Profiles of 4W-glpD–glpK. b Profiles 4WA. Squares represent residual glycerol, circles represent cell growth, triangles represent l-serine. Values denote the average of three independent experiments, and error bars indicate standard deviation Notes Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Copyright information © Society for Industrial Microbiology and Biotechnology 2019 Authors and Affiliations Xiaomei Zhang1Dong Zhang1Jiafen Zhu1Wang Liu1Guoqiang Xu23Xiaojuan Zhang23Jinsong Shi1Zhenghong Xu23Email author1.Laboratory of Pharmaceutical Engineering, School of Pharmaceutics ScienceJiangnan UniversityWuxiPeople’s Republic of China2.National Engineering Laboratory for Cereal Fermentation TechnologyJiangnan UniversityWuxiPeople’s Republic of China3.The Key Laboratory of Industrial Biotechnology, Ministry of Education, School of BiotechnologyJiangnan UniversityWuxiPeople’s Republic of China


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Xiaomei Zhang, Dong Zhang, Jiafen Zhu, Wang Liu, Guoqiang Xu, Xiaojuan Zhang, Jinsong Shi, Zhenghong Xu. Correction to: High-yield production of l-serine from glycerol by engineered Escherichia coli, Journal of Industrial Microbiology & Biotechnology, 2019, 1-3, DOI: 10.1007/s10295-019-02163-9