Flavonoids of Caragana frutex

FLAVONOIDS OF Caragana frutex UDC 547.9:582.736 V. V. Boinik and V. M. Kovalev We have continued a study of the chemical study of the epigeal part of Caragana frutex C. Koch (Russian pea shrub) collected in the flowering phase in the environs of Kharkov [I]. The chromatographic separation of an ethereal fraction on a polyamide column [eluting solvents, chloroform and chloroform-ethanol (9:1), (8:2), and (7:3)] yielded five substances of flavonoid nature (I-V). Substance (I) - C16HI2Os, mp 259-261°C, Ama "C2H2OH C2HsONa" x : 269, 302 sh, 328 nm; Ima x . 276, AICIa: 259, 277, 293 sh, 302, 345, 383 nm; CHaCOONa 296 sh, 365 nm; ima x Ima x : 276, 298 sh, 359nm; CH3COONa+H3BO3 , , Ima x : 269 309 sh 332 nm; was identified as acacetin. Substance (II) - C16H1207, mp 303-305°C ' X- mC2HsOH" 253, 267 sh, 307 sh, 326 sh, 371 nm; ax IC2H~ONa CH~COONa. max : 240 sh, 271, 329, 436 nm; maxiAiCl3: 264, 304 sh, 362 sh, 432 nm', Ama x . 260 sh, CH~COONa+H3BO 3 274, 321, 394 nm; Ima x : 264, 304 sh, 362 sh, 432 nm; was identified as isorhamnetin. Substance ( I I I ) - ClsH100 ~, mp 275-277°C, was identical with kaempferol; substance (IV) - C15HIoOv, mp 314-316°C, was identical with quercetin; and substance (V) - Cl~H100 s, mp 354-356°C, was identical with myricetin. The substances isolated were identified by the chromatographic icochemical properties in comparison with an authentic sample [2]. behavior and their phys- This is the first time that flavonoids have been isolated from Caragana frutex. LITERATURE CITED 1. V. V. Boinik. V. N. Kovalev, and N. F. Komissarenko, et al., Khim. Prir. Soedin., 780 (1983). 2. L. K. Klyshev, V. A. Bandyukova, and L. S. Alyukina, Nauka KazSSR, Alma-Ata (1978), p. 220. Plant Flavonoids [in Russian], Kharkov State Pharmaceutical Institute. Translated from Khimiya Prirodnykh Soedinenii, No. 4, pp. 599, July-August, 1987. Original article submitted March 2, 1987. 504 0009-3130/87/2304-0504512.50 © 1988 Plenum Publishing Corporation  (...truncated)