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Braincase simplification and the origin of lissamphibians

Dissorophoidea, a group of temnospondyl tetrapods that first appear in the Late Carboniferous, is made up of two clades ⎼ Olsoniformes and Amphibamiformes (Branchiosauridae and Amphibamidae) ⎼ the latter of which is widely thought to have given rise to living amphibians (i.e., Lissamphibia). The lissamphibian braincase has a highly derived morphology with several secondarily lost...

Review of The Archaeology of Andean Pastoralism edited by José M. Capriles and Nicholas Tripcevich

Book detailsCapriles J M and Tripcevich N (eds.) The Archaeology of Andean Pastoralism Albuquerque: University of New Mexico Press; 2016.280 pages, 87 figures, 25 tablesISBN 978-0-8263-5702-1

Interaction with hyaluronan matrix and miRNA cargo as contributors for in vitro potential of mesenchymal stem cell-derived extracellular vesicles in a model of human osteoarthritic synoviocytes

BackgroundOsteoarthritis (OA) is the most prevalent joint disease, and to date, no options for effective tissue repair and restoration are available. With the aim of developing new therapies, the impact of mesenchymal stem cells (MSCs) has been explored, and the efficacy of MSCs started to be deciphered. A strong paracrine capacity relying on both secreted and vesicle-embedded...

Legacy habitat contamination as a limiting factor for Chinook salmon recovery in the Willamette Basin, Oregon, USA

In the western United States, the long-term recovery of many Pacific salmon populations is inextricably linked to freshwater habitat quality. Industrial activities from the past century have left a legacy of pollutants that persist, particularly near working waterfronts. The adverse impacts of these contaminants on salmon health have been studied for decades, but the population...

The increasing incidence of surgically treated quadriceps tendon ruptures

PurposeDue to increased life expectancy and a more active life style of the older people, we hypothesised that the incidence of quadriceps tendon rupture (QTR) is higher than previously reported. The objective of this nationwide population-based study was to investigate the annual incidence of QTR in patients who underwent operative treatment in Finland between 1997 and 2014...

Memories and prevalence of posttraumatic stress disorder in intensive care units

The present study evaluated the prevalence of PTSD indicators in patients who had to be hospitalized in ICU six months after being discharged and examined the relationship between PTSD and mnemonic memories. Participants were 41 adult patients with different diseases who answered questionnaires about PTSD, memory and clinical information. It was identified that 24.4% of the...

A86 EXPLORING GENE-ENVIRONMENT INTERACTIONS IN CROHN’S DISEASE: THE EFFECT OF VITAMIN D DEFICIENCY ON INTESTINAL HOMEOSTASIS IN THE CONTEXT OF SUSCEPTIBILITY GENE NOD2L1007FS

Recent studies have implicated vitamin D deficiency in IBD susceptibility and outcomes. Although the mechanisms through which vitamin D affects IBD are not yet understood, emerging evidence from our lab and others demonstrate a role of vitamin D deficient signaling in dysregulating autophagy. In addition, vitamin D can modulate host immune responses and may play a role in...

Hidden expectations: scaffolding subject specialists’ genre knowledge of the assignments they set

Subject specialists’ knowledge of academic and disciplinary literacy is often tacit. We tackle the issue of how to elicit subject specialists’ tacit knowledge in order to develop their pedagogical practices and enable them to communicate this knowledge to students. Drawing on theories of genre and metacognition, a professional development activity was designed and delivered. Our...

Survey design for broad-scale, territory-based occupancy monitoring of a raptor: Ferruginous hawk (Buteo regalis) as a case study

Given the uncertain population status of low-density, widely-occurring raptors, monitoring changes in abundance and distribution is critical to conserving populations. Nest-based monitoring is a common, useful approach, but the difficulty and expense of monitoring raptor nests and importance of reliable trend data to conservation requires that limited resources are allocated...

Lewy Body Dementia Association’s Research Centers of Excellence Program: Inaugural Meeting Proceedings

The first Lewy Body Dementia Association (LBDA) Research Centers of Excellence (RCOE) Investigator’s meeting was held on December 14, 2017, in New Orleans. The program was established to increase patient access to clinical experts on Lewy body dementia (LBD), which includes dementia with Lewy bodies (DLB) and Parkinson’s disease dementia (PDD), and to create a clinical trials...

The management of social problems talk in a support group

The comprehension of the health-disease process from a multifactorial perspective has allowed important transformations in the healthcare practices. In this article, we discuss the use of the support group as a resource for mental health care, analyzing how conversations about social issues are managed in this context. Based on contributions from the social constructionist...

Enhanced di-Higgs production in the two Higgs doublet model

Abstract We show that the rate for di-Higgs production at the LHC can be enhanced by a factor as large as 25 compared to the Standard Model value in the two Higgs doublet model, while being consistent with the known properties of the observed Higgs boson h. There are correlated modifications in \( t\overline{t}h \) and resonant Zh production rates, which can serve as tests of...

Description of a new species of Surazomus (Arachnida: Schizomida), with comments on homology of male flagellum and mating march anchorage in the genus

Surazomus saturninoae sp. nov. is described from eastern Amazon. The male has a pentagonal flagellum, similar to those of three other species in the genus. These four species are herein gathered as the arboreus-group of Surazomus. We present a brief synopsis of chaetotaxy description in hubbardiines and several homology proposals for the flagellum of the species in the arboreus...

Long-term field study on stabilization of contaminated wastes by growing clonally reproduced Silene vulgaris calamine ecotype

AimsPseudo-metallophyte Silene vulgaris frequently colonizes polluted areas. We investigated whether plants obtained under in vitro conditions can be used to form long-term communities on zinc-lead tailings rich in cadmium. To this end, we checked the species stabilization capacity and biochemical properties of the area subjected to long-term cultivation of a local S vulgaris...

Scalar field as a null dust

We show that a canonical, minimally coupled scalar field which is non-self interacting and massless is equivalent to a null dust fluid (whether it is a test or a gravitating field), in a spacetime region in which its gradient is null. Under similar conditions, the gravitating and nonminimally coupled Brans-Dicke-like scalar of scalar-tensor gravity, instead, cannot be represented...

The consequences of disclosing key audit matters (KAMs): A review of the academic literature

Recent years have witnessed a change in the auditor reporting model. One of these developments is the auditor’s issuance of so-called Key Audit Matters in the auditor’s report, where they disclose “those matters that, in the auditor’s professional judgment, were of most significance in the audit of the financial statements of the current period”. In this paper, we review the...

Gene expression profiles between cystic and solid vestibular schwannoma indicate susceptible molecules and pathways in the cystic formation of vestibular schwannoma

Previous research has shown that although NF2 gene mutation is the major cause of vestibular schwannoma (VS), it may not directly participate in cystic VS (CVS). To elucidate the underlying potential genetic mechanisms in the cystic formation of VS, we compared differences in gene expression between solid VS (SVS) and CVS via a bioinformatics analysis. The cDNA microarray method...

Effects of Food on the Bioavailability of Amphetamine in Healthy Adults After Administration of SHP465 Mixed Amphetamine Salts Extended-Release Capsules

Background and objectiveSHP465 mixed amphetamine salts extended release is a once-daily, single-entity, mixed amphetamine salts capsule product for attention-deficit/hyperactivity disorder. The objective of this study was to evaluate amphetamine pharmacokinetics following SHP465 mixed amphetamine salts under three administration conditions.MethodsHealthy adults (n = 16) enrolled...

Aicardi–Goutières Syndrome associated mutations of RNase H2B impair its interaction with ZMYM3 and the CoREST histone-modifying complex

DNA-RNA hybrids arise in all cell types, and are removed by multiple enzymes, including the trimeric ribonuclease, RNase H2. Mutations in human RNase H2 result in Aicardi–Goutières syndrome (AGS), an inflammatory brain disorder notable for being a Mendelian mimic of congenital viral infection. Previous studies have shown that several AGS-associated mutations of the RNase H2B...

Correction: The PIKfyve complex regulates the early melanosome homeostasis required for physiological amyloid formation (doi:10.1242/jcs.229500)

There was an error in J. Cell Sci. (2019) 132, [jcs229500][1] ([doi:10.1242/jcs.229500][2]). The DMSO lanes in [Fig. 2][3]C and D were duplicated in [Fig. 2][3]E and F, respectively, which contravenes our image presentation guidelines. The authors supplied full blots for all these panels and

Concurrent infections of dengue virus serotypes in Bali, Indonesia

ObjectiveTo describe cases of dengue virus (DENV) concurrent infections in patients from both local and international traveler visiting Bali, Indonesia.ResultsDuring a hospital-based study, 260 patients (from 161 local and 99 international traveler patients) were recruited. Among them, 190 were positive by DENV RT-PCR in which eight patients (five local and three international...

Isolated condylar fractures diagnosed by post mortem computed tomography

Due to their anatomical location, occipital condylar fractures (OCFs) are usually not observed during traditional autopsies and are therefore considered a rare injury. The aim of this study was to determine the true frequency of OCFs using post-mortem computed tomography (PMCT) in traumatic casualties. We retrospectively analyzed 438 PMCT studies of victims of traffic accidents...