Recently added

A mass sacrifice of children and camelids at the Huanchaquito-Las Llamas site, Moche Valley, Peru

Here we report the results of excavation and interdisciplinary study of the largest child and camelid sacrifice known from the New World. Stratigraphy, associated artifacts, and radiocarbon dating indicate that it was a single mass killing of more than 140 children and over 200 camelids directed by the Chimú state, c. AD 1450. Preliminary DNA analysis indicates that both boys and...

The Trichopterygini (Lepidoptera, Geometridae) of Austral South America: description of new species from Chile

Four new species belonging to the genera Hoplosauris Butler, Butleriana Parra, Warrenaria Parra, and Fueguina Parra from south-central Chile are described. The species are H. morenoi Ramos-González & Parra, sp. n., B. phoenix Ramos-González & Parra, sp. n., W. onca Ramos-González & Parra, sp. n., and F. araucana Ramos-González & Parra, sp. n. The genus Aloba Warren is reassigned...

“She’s gone now.” A mixed methods analysis of the experiences and perceptions around the deaths of children who died unexpectedly in health care facilities in Cape Town, South Africa

Purpose The sudden death of a child is a catastrophic event for both the family and the healthcare workers involved. Confidential enquiries provide a biomedical depiction of the processes and quality of care delivered and drive improvements in care. However, these rarely include an assessment of the patient/caregiver experience which is increasingly regarded as a key measure of...

Genetics of Bone and Muscle Interactions in Humans

Purpose of ReviewTo summarize the evidence from recent studies on the shared genetics between bone and muscle in humans.Recent FindingsGenome-wide association studies (GWAS) have successfully identified a multitude of loci influencing the variability of different bone or muscle parameters, with multiple loci overlapping between the traits. In addition, joint analyses of multiple...

CP symmetries as guiding posts: revamping tri-bi-maximal mixing. Part I

Abstract We analyze the possible generalized CP symmetries admitted by the Tri-Bi-Maximal (TBM) neutrino mixing. Taking advantage of these symmetries we construct in a systematic way other variants of the standard TBM Ansatz. Depending on the type and number of generalized CP symmetries imposed, we get new mixing matrices, all of which related to the original TBM matrix. One of...

Effects of larval density on dispersal and fecundity of western corn rootworm, Diabrotica virgifera virgifera LeConte (Coleoptera: Chrysomelidae)

The western corn rootworm, Diabrotica virgifera virgifera (LeConte) (Coleoptera: Chrysomelidae), is an economically important pest of corn in the northern United States. Some populations have developed resistance to management strategies including transgenic corn that produces insecticidal toxins derived from the bacterium Bacillus thuringiensis (Bt). Knowledge of insect...

The organizational implications of Brexit

This point-of-view article examines the organizational implications of the UK’s exit from the European Union (Brexit). We identify the effects of Brexit on firms’ transaction costs in cross-border trade within Europe and highlight the importance of EU residency to secure licenses to operate. We also address how access to skilled labor may be affected by rising restrictions to...

Control of grey rot of apple fruits by biologically active natural products

Biorend SC (chitosan), BC-1000 EC (grapefruit extract plus bioflavonoids) and ECO-100 SC (bioflavonoids plus organic acids, citric phytoalexins, fatty acids, glycerides and sugars), respectively, suppressed grey rot of apple caused by B. cinerea by 80.1%, 79.0% and 76.5% when used as post-harvest treatments under controlled conditions. When applied as combined pre- and post...

A five-gene signature predicts overall survival of patients with papillary renal cell carcinoma

Background The present study aims to investigate the gene expression changes in papillary renal cell carcinoma(pRCC) and screen several genes and associated pathways of papillary renal cell carcinoma progression. Methods The papillary renal cell carcinoma RNA sequencing (RNA-seq) data set was downloaded from TCGA (The Cancer Genome Atlas). We identified the differentially...

Pt embedded Ni3Se2@NiOOH core-shell dendrite-like nanoarrays on nickel as bifunctional electrocatalysts for overall water splitting

Developing high-performance bifunctional catalysts toward hydrogen evolution reaction (HER) and oxygen evolution reaction (OER) is essential to enhance water splitting efficiency for large-scale hydrogen production. Neither noble metal Pt nor transition metal compounds show satisfactory performances for both HER and OER simultaneously. Here, we prepared a three-dimensional Pt...

Draft genome sequence of Enterococcus faecium SP15, a potential probiotic strain isolated from spring water

ObjectivesEnterococci are Gram-positive lactic acid bacteria and common inhabitants of the gastrointestinal tract of mammals, including humans. They are also widely distributed in diverse environments such as soil, water, vegetables and food. Enterococcus faecium is able to produce antimicrobial compounds (enterocins) and thus can act as a probiotic. E. faecium SP15 is a newly...

Clinical protein science in translational medicine targeting malignant melanoma

Melanoma of the skin is the sixth most common type of cancer in Europe and accounts for 3.4% of all diagnosed cancers. More alarming is the degree of recurrence that occurs with approximately 20% of patients lethally relapsing following treatment. Malignant melanoma is a highly aggressive skin cancer and metastases rapidly extend to the regional lymph nodes (stage 3) and to...

Real-time adaptive planning method for radiotherapy treatment delivery for prostate cancer patients, based on a library of plans accounting for possible anatomy configuration changes

Background and purpose In prostate cancer treatment with external beam radiation therapy (EBRT), prostate motion and internal changes in tissue distribution can lead to a decrease in plan quality. In most currently used planning methods, the uncertainties due to prostate motion are compensated by irradiating a larger treatment volume. However, this could cause underdosage of the...

Bleaching impacts on carbonate production in the Chagos Archipelago: influence of functional coral groups on carbonate budget trajectories

Reefs in the remote Chagos Archipelago (central Indian Ocean) were severely affected by sea surface temperature warming and coral bleaching in 2015–2016. Here we assess the impacts of this event on community composition and reef carbonate production at twelve fore reefs sites across three atolls. Bleaching caused a 69% decline in coral cover, mostly driven by mortality of tabular...

Canadian Nursing Students’ Experiences with Medical Assistance in Dying / Les expériences d’étudiantes en sciences infirmières au regard de l’aide médicale à mourir

The recent introduction of medical assistance in dying (MAiD) has significant implications for healthcare workers, nurse educators, and society at large. Nursing students are being asked to participate directly or indirectly with a medically assisted death. Little is known about nursing students’ experiences with or attitudes toward MAiD in Canada.The purpose of this study was to...

Influence of Crohn’s disease related polymorphisms in innate immune function on ileal microbiome

We have previously identified NOD2 genotype and inflammatory bowel diseases (IBD) phenotype, as associated with shifts in the ileal microbiome (“dysbiosis”) in a patient cohort. Here we report an integrative analysis of an expanded number of Crohn's disease (CD) related genetic defects in innate immune function (NOD2, ATG16L1, IRGM, CARD9, XBP1, ORMDL3) and composition of the...

Early Initiation and Exclusivity of Breastfeeding in Rural Zimbabwe: Impact of a Breastfeeding Intervention Delivered by Village Health Workers

Suboptimal breastfeeding contributes to >800,000 global child deaths annually. Optimal breastfeeding includes early initiation (EI) and exclusive breastfeeding (EBF) for the first 6 mo.