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Shrubs indirectly increase desert seedbanks through facilitation of the plant community

The mechanisms supporting positive ecological interactions are important. Foundation species can structure desert biodiversity by facilitating seedbanks of annual plants, but the direct and indirect mechanisms of shrub effects on seedbank have not been experimentally decoupled. We conducted the first test of shrubs increasing seedbank densities through direct effects on the...

Casp8 hypomethylation and neural tube defects in association with polycyclic aromatic hydrocarbon exposure

BackgroundEpidemiological studies have found that prenatal exposure to polycyclic aromatic hydrocarbons (PAHs) is associated with increased risk for neural tube defects (NTDs). Aberrant DNA methylation, excessive apoptosis, and oxidative stress have been implied as the mechanism underlying the association between PAH exposure and NTDs, respectively. However, the role of DNA...

Influenza Vaccine Effectiveness and Statin Use Among Adults in the United States, 2011–2017

Statin medications have immunomodulatory effects. Several recent studies suggest that statins may reduce influenza vaccine response and reduce influenza vaccine effectiveness (VE).

Curious George's 5-Minute Stories

Ill-mannered Lulu wants a brontosaurus for a pet. It is her birthday and she always gets what she wants! After her parents say no, Lulu sets off into the forest alone, hoping to find a brontosaurus herself. She sings a ridiculous and loud song as she skips through the woods. Her singing attracts a big bear, a hungry tiger, and a seething snake. Lulu puts each of these predators...

An Evaluation of the National Greening Program Implementation in Simala, Cebu Philippines Utilizing ABCD Model

This descriptive-evaluative study is an evaluation of the effectiveness of the implementation of the National Greening Program in Simala National High School, a secondary public school in Cebu, Philippines utilizing the ABCD model. It identified the congruences and discrepancies of the intents and actualities of the following components: A - the participants, B - programs and...

Functions of mountain pine beetle cytochromes P450 CYP6DJ1, CYP6BW1 and CYP6BW3 in the oxidation of pine monoterpenes and diterpene resin acids

The mountain pine beetle (MPB; Dendroctonus ponderosae) is a forest insect pest that attacks several different pine (Pinus) species in its native range of distribution in western North America. MPB are exposed for most of their life cycle to the chemical defenses of their hosts. These defenses are dominated by oleoresin secretions containing mostly various monoterpenes and...

Lifestyle and psychosocial factors and a decline in competence in daily living among Japanese early elderly people: from an age-specified community-based cohort study (NISSIN project)

BackgroundTo let the early elderly live well, understanding how lifestyle and psychosocial factors related to a decline in competence in daily living is important.MethodsWe investigated the associations between lifestyle and psychosocial factors at age 64 years and a decline in the Tokyo Metropolitan Institute of Gerontology Index of Competence score of ≥ 2 points at age 70 years...

Relationship between neuropsychological and clinical aspects and suicide attempts in euthymic bipolar patients

Some studies have investigated the possible relationship between suicide attempts and impulsivity in patients with bipolar disorder. The objective of this study was to assess the relationship between neuro-psychological and clinical aspects and suicide behavior in euthymic bipolar patients. The Iowa Gambling Task and the Conner's Continuous Performance Test evaluated impulsivity...

Is Burnout Infectious? Understanding Drivers of Burnout and Job Satisfaction Among Academic Infectious Diseases Physicians

Burnout is pervasive in academic medicine. We administered the Maslach Burnout Inventory and an Infectious Diseases (ID) job description survey to our ID faculty. Respondents’ burnout (>50%) and job satisfaction (>90%) were each high. Although burnout may be balanced by job satisfaction, the relationship between the 2 deserves further study.

Design and implementation of AD9361-based software radio receiver

Existing software radio platforms constructed by discrete devices have many disadvantages, such as high power consumption, high cost, and poor portability. In this study, an AD9361-based software radio communication system was designed on the basis of the zero-IF bandpass sampling software radio structure to solve the poor universality and expansibility problem of traditional...

Out-of-pocket payments, vertical equity and unmet medical needs in France: A national multicenter prospective study on lymphedema

Out-of-pocket payments might threaten the vertical equity of financing and generate unmet medical needs. The main objective was to assess the vertical equity of outpatient out-of-pocket payments for lymphedema patients in France. Twenty-seven centres, among which 11 secondary care hospitals and 16 primary care practices participated in this prospective national multicenter study...

Propidium iodide staining underestimates viability of adherent bacterial cells

Combining membrane impermeable DNA-binding stain propidium iodide (PI) with membrane-permeable DNA-binding counterstains is a widely used approach for bacterial viability staining. In this paper we show that PI staining of adherent cells in biofilms may significantly underestimate bacterial viability due to the presence of extracellular nucleic acids (eNA). We demonstrate that...

Complementary Observables in Quantum Mechanics

We review the notion of complementarity of observables in quantum mechanics, as formulated and studied by Paul Busch and his colleagues over the years. In addition, we provide further clarification on the operational meaning of the concept, and present several characterisations of complementarity—some of which new—in a unified manner, as a consequence of a basic factorisation...

Love Sucks

By Emily Lane, Published on 04/08/19

Construction with opposition: cardinal invariants and games

We consider several game versions of the cardinal invariants \({\mathfrak {t}}\), \({\mathfrak {u}}\) and \({\mathfrak {a}}\). We show that the standard proof that parametrized diamond principles prove that the cardinal invariants are small actually shows that their game counterparts are small. On the other hand we show that \({\mathfrak {t}}<{\mathfrak {t}}_{Builder}\) and...

Properties of face localizer activations and their application in functional magnetic resonance imaging (fMRI) fingerprinting

Functional localizers are particularly prevalent in functional magnetic resonance imaging (fMRI) studies concerning face processing. In this study, we extend the knowledge on face localizers regarding four important aspects: First, activation differences in occipital and fusiform face areas (OFA/FFA) and amygdala are characterized by increased activation while precuneus and...

Best practices for identifying men who have sex with men for corrections-based pre-exposure prophylaxis provision

PurposeMen who have sex with men (MSM) who are incarcerated are at increased risk for HIV acquisition, yet there are challenges associated with disclosing sexual identity/orientation among people who are incarcerated.MethodsThe current study used semi-structured, qualitative interviews to explore attitudes and awareness of pre-exposure prophylaxis (PrEP) among 26 MSM who were...

Pricing Chinese Convertible Bonds with Default Intensity by Monte Carlo Method

This article proposes a new way to price Chinese convertible bonds by the Longstaff-Schwartz Least Squares Monte Carlo simulation. The default intensity and the volatility are the two important parameters, which are difficultly obtained in the emerging market, in pricing convertible bonds. By developing the Merton theory, we find a new effective method to get the theoretical...

Ophthalmic Surgery in Patients with Left Ventricular Assist Devices

The newer generation of left ventricular assist devices (LVADs) are commonly used as destination therapy; these devices have demonstrated improved outcomes and increased survival. Given the longer lifespan, it is not surprising that patients with LVADS are increasingly presenting with noncardiac, chronic diseases and interventions for their treatment. This includes ophthalmic...

Long-term Pooled Safety Analysis of Palbociclib in Combination With Endocrine Therapy for HR+/HER2- Advanced Breast Cancer

Palbociclib administered with endocrine therapy was tolerable when the overall incidence of toxicities was assessed separately for three PALOMA studies. This study analyzed pooled, longer-term PALOMA safety data longitudinally.

Single nucleotide polymorphism assay to distinguish barley (Hordeum vulgare L.) varieties in support of seed certification

Seed certification of barley (Hordeum vulgare L.) involves scoring morphological characteristics to determine the variety in field plots which is expensive and time consuming. In order to establish whether molecular tests can identify the barley variety we have developed a molecular test to be used on seed. The molecular test genotypes the seed samples using 38 Single Nucleotide...

Stepwise Fabrication of Co-Embedded Porous Multichannel Carbon Nanofibers for High-Efficiency Oxygen Reduction

A novel nonprecious metal material consisting of Co-embedded porous interconnected multichannel carbon nanofibers (Co/IMCCNFs) was rationally designed for oxygen reduction reaction (ORR) electrocatalysis. In the synthesis, ZnCo2O4 was employed to form interconnected mesoporous channels and provide highly active Co3O4/Co core–shell nanoparticle-based sites for the ORR. The IMC...

‘Animals Are Their Best Advocates’: Interspecies Relations, Embodied Actions, and Entangled Activism

Since 1986, the Coalition Against Duck Shooting (CADS) has sought to ban the practice of recreational duck hunting across Australia. Campaigners have developed techniques to disrupt shooters, rescue injured water birds, and gain media coverage. The campaign is underpinned by embodied processes that engage empathy, emotion, affect, and cognition. Seeking to understand human-animal...

Full Bayesian Comparative Phylogeography from Genomic Data

A challenge to understanding biological diversification is accounting for community-scale processes that cause multiple, co-distributed lineages to co-speciate. Such processes predict non-independent, temporally clustered divergences across taxa. Approximate-likelihood Bayesian computation (ABC) approaches to inferring such patterns from comparative genetic data are very...