Advanced search    

Search: authors:"Dong Zhang"

351 papers found.
Use AND, OR, NOT, +word, -word, "long phrase", (parentheses) to fine-tune your search.

Neck Circumference Positively Related With Central Obesity, Overweight, and Metabolic Syndrome in Chinese Subjects With Type 2 Diabetes: Beijing Community Diabetes Study 4

GUANG-RAN YANG MM SHEN-YUAN YUAN MB HAN-JING FU MM GANG WAN MM LIANG-XIANG ZHU MB XIANG-LEI BU MB JIAN-DONG ZHANG MB C a r d i o v a s c u l a r a n d OBJECTIVE - To investigate the association

Mapping susceptibility loci for alcohol consumption using number of grams of alcohol consumed per day as a phenotype measure

Background There is substantial evidence for a significant genetic component to the risk for alcoholism. However, susceptibility loci or genes for alcohol dependence remain largely unknown. To identify susceptibility loci for alcohol dependence, we selected 329 extended families from the Framingham Heart Study population in which at least one family member reported alcohol...

Mapping susceptibility loci for alcohol consumption using number of grams of alcohol consumed per day as a phenotype measure

There is substantial evidence for a significant genetic component to the risk for alcoholism. However, susceptibility loci or genes for alcohol dependence remain largely unknown. To identify susceptibility loci for alcohol dependence, we selected 329 extended families from the Framingham Heart Study population in which at least one family member reported alcohol consumption...

High-Density Genetic Linkage Map Construction and QTL Mapping of Grain Shape and Size in the Wheat Population Yanda1817 × Beinong6

High-density genetic linkage maps are necessary for precisely mapping quantitative trait loci (QTLs) controlling grain shape and size in wheat. By applying the Infinium iSelect 9K SNP assay, we have constructed a high-density genetic linkage map with 269 F 8 recombinant inbred lines (RILs) developed between a Chinese cornerstone wheat breeding parental line Yanda1817 and a high...

Erratum: Camelid genomes reveal evolution and adaptation to desert environments

Mohammed H. Abutarboush Yanping Xing Zhiyuan Xie Ali S. Alshanqeeti Yanru Zhang Qiulin Yao Badr M. Al-Shomrani Dong Zhang Jiang Li Manee M. Manee Zili Yang Linfeng Yang Yiyi Liu Jilin Zhang Musaad A

A Mechanistic Paradigm for Broad-Spectrum Antivirals that Target Virus-Cell Fusion

LJ001 is a lipophilic thiazolidine derivative that inhibits the entry of numerous enveloped viruses at non-cytotoxic concentrations (IC50≤0.5 µM), and was posited to exploit the physiological difference between static viral membranes and biogenic cellular membranes. We now report on the molecular mechanism that results in LJ001's specific inhibition of virus-cell fusion. The...

SALL1, the gene mutated in Townes–Brocks syndrome, encodes a transcriptional repressor which interacts with TRF1/PIN2 and localizes to pericentromeric heterochromatin

Zhang, Department of Medicine III, University of Munich, and GSF, Clinical Cooperative Group 'Leukemia' , Marchioninistrasse 25, 81377 Munchen , Germany 1 Institute of Anthropology and Human Genetics

Expression and localization of VCX/Y proteins and their possible involvement in regulation of ribosome assembly during spermatogenesis

Union Medical College, 5 Dong Dan 3-tiao, Beijing 100005, ChinaSheng Wei ZOU, Xiao Dong ZHANG, Shi Ying MIAO, Qi SHENG & Lin Fang WANGNational Research Institute for Family Planing, WHO Collaboration ... Jian Chao ZHANG in:Nature Research journals • PubMed • Google ScholarSearch for Xiao Dong ZHANG in:Nature Research journals • PubMed • Google ScholarSearch for Shi Ying MIAO in:Nature Research journals

Identification of differentially expressed genes of primary spermatocyte against round spermatid isolated from human testis using the laser capture microdissection technique

The method of laser capture microdissection (LCM) combined with suppressive subtractive hybridization (SSH) was developed to isolate specific germ cells from human testis sections and to identify the genes expressed during differentiation and development. In the present study, over 10,000 primary spermatocytes and round spermatid cells were successfully isolated by LCM. Using the...

Exposure of Brown Norway Rats to Diesel Exhaust Particles Prior to Ovalbumin (OVA) Sensitization Elicits IgE Adjuvant Activity but Attenuates OVA-Induced Airway Inflammation

Exposure to diesel exhaust particles (DEP) during the sensitization process has been shown to increase antigen-specific IgE production and aggravate allergic airway inflammation in human and animal models. In this study, we evaluated the effect of short-term DEP exposure on ovalbumin (OVA)-mediated responses using a post-sensitization model. Brown Norway rats were first exposed...

Apoptosis and Growth Inhibition in Malignant Lymphocytes After Treatment With Arsenic Trioxide at Clinically Achievable Concentrations

BACKGROUND: Arsenic trioxide (As2O3) can induce clinical remission in patients with acute promyelocytic leukemia via induction of differentiation and programmed cell death (apoptosis). We investigated the effects of As2O3 on a panel of malignant lymphocytes to determine whether growth-inhibitory and apoptotic effects of As2O3 can be observed in these cells at clinically...