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Tespa1 regulates T cell receptor-induced calcium signals by recruiting inositol 1,4,5-trisphosphate receptors

, Hangzhou 310058, ChinaLinrong Lu AuthorsSearch for Jingjing Liang in:Nature Research journals • PubMed • Google ScholarSearch for Jun Lyu in:Nature Research journals • PubMed • Google ScholarSearch for Meng ... Zhao in:Nature Research journals • PubMed • Google ScholarSearch for Dan Li in:Nature Research journals • PubMed • Google ScholarSearch for Mingzhu Zheng in:Nature Research journals • PubMed • Google

ATP Binding Cassette Transporter ABCA7 Regulates NKT Cell Development and Function by Controlling CD1d Expression and Lipid Raft Content

Marcovecchio Farah Andary Meng Zhao Michael L. Fitzgerald Mitchell Kronenberg Catherine C. Hedrick1 OPEN ABCA7 is an ABC transporter expressed on the plasma membrane, and actively exports phospholipid complexes

Glycine increases preimplantation development of mouse oocytes following vitrification at the germinal vesicle stage

Ice-free cryopreservation, referred to as vitrification, is receiving increased attention in the human and animal assisted reproduction. However, it introduces the detrimental osmotic stress by adding and removing high contents of cryoprotectants. In this study, we evaluated the effects of normalizing cell volume regulation by adding glycine, an organic osmolyte, during...

Effects of Herb-Partitioned Moxibustion on the miRNA Expression Profiles in Colon from Rats with DSS-Induced Ulcerative Colitis

, Yan Huang, Hong-sheng Dong, Ji-meng Zhao, and Chuan-zi Dou established the animal model and performed the molecular experiments. Yan Huang, Zhe Ma, Yun-hua Cui, and Hui-rong Liu analyzed the data. Yan

Effects of Herb-Partitioned Moxibustion on the miRNA Expression Profiles in Colon from Rats with DSS-Induced Ulcerative Colitis

, Yan Huang, Hong-sheng Dong, Ji-meng Zhao, and Chuan-zi Dou established the animal model and performed the molecular experiments. Yan Huang, Zhe Ma, Yun-hua Cui, and Hui-rong Liu analyzed the data. Yan

Robust Tube-Based MPC with Piecewise Affine Control Laws

2014 Academic Editor: Józef Banaś Copyright © 2014 Meng Zhao and Xiaoming Tang. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted

A Generalized Minimum Cost Flow Model for Multiple Emergency Flow Routing

During real-life disasters, that is, earthquakes, floods, terrorist attacks, and other unexpected events, emergency evacuation and rescue are two primary operations that can save the lives and property of the affected population. It is unavoidable that evacuation flow and rescue flow will conflict with each other on the same spatial road network and within the same time window...

Cold sensitivity of TRPA1 is unveiled by the prolyl hydroxylation blockade-induced sensitization to ROS

Sciences, Kyoto University, 46-29 Yoshida-Shimoadachi-cho, Sakyo-ku 606-8501, JapanTakahito Miyake, Saki Nakamura, Meng Zhao, Kanako So, Hisashi Shirakawa, Takayuki Nakagawa & Shuji KanekoDepartment of ... journals • PubMed • Google ScholarSearch for Meng Zhao in:Nature Research journals • PubMed • Google ScholarSearch for Kanako So in:Nature Research journals • PubMed • Google ScholarSearch for Keisuke Inoue

Dyslipidemia in rural areas of North China: prevalence, characteristics, and predictive value

Background The prevalence of cardiovascular disease has been increasing worldwide. As a common pathogenic risk factor, dyslipidemia played a great role in the incidence and progress of these diseases. We investigated to achieve accurate and up-to-date information on the prevalence of dyslipidemia and its associations with other lipid-related diseases in rural North China. Methods...

The Likelihood Ranking Methods for Interval Type-2 Fuzzy Sets Considering Risk Preferences

Editor: Dan Simon Copyright © 2015 Meng Zhao et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and

The Likelihood Ranking Methods for Interval Type-2 Fuzzy Sets Considering Risk Preferences

Editor: Dan Simon Copyright © 2015 Meng Zhao et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and

NERF encodes a RING E3 ligase important for drought resistance and enhances the expression of its antisense gene NFYA5 in Arabidopsis

NFYA5 is an important drought-stress inducible transcription factor gene that is targeted by miR169 in Arabidopsis. We show here that the cis-natural antisense transcript gene of NFYA5, NFYA5 Enhancing RING FINGER (NERF), can produce siRNAs from their overlapping region (OR) and affect NFYA5 transcripts by functioning together with miR169. The NERF protein functions as an E3...

Oscillating primary transcripts harbor miRNAs with circadian functions

. Author information AffiliationsCAS-MPG Partner Institute for Computational Biology, Shanghai 200031, ChinaHaifang Wang, Zenghua Fan, Meng Zhao, Juan Li & Jun YanInstitute of Neuroscience, CAS Center for ... Excellence in Brain Science and Intelligence Technology, Shanghai 200031, ChinaHaifang Wang, Meng Zhao & Jun YanInstitute for Biochemistry and Cell Biology, Shanghai 200031, ChinaMinghua Lu & Mofang

Hiwi Promotes the Proliferation of Colorectal Cancer Cells via Upregulating Global DNA Methylation

Hiwi is well known for its role in stem cell renewal, maintaining the resting stage, and downregulating cell cycle of stem cells via RNA silencing. And Hiwi overexpression has been recognized in several types of cancers. In the present study, we examined the Hiwi expression in colorectal cancer (CRC) specimens in both mRNA and protein levels via real-time quantitative PCR...

Hiwi Promotes the Proliferation of Colorectal Cancer Cells via Upregulating Global DNA Methylation

Hiwi is well known for its role in stem cell renewal, maintaining the resting stage, and downregulating cell cycle of stem cells via RNA silencing. And Hiwi overexpression has been recognized in several types of cancers. In the present study, we examined the Hiwi expression in colorectal cancer (CRC) specimens in both mRNA and protein levels via real-time quantitative PCR...

Rubipodanin A, the First Natural N-Desmonomethyl Rubiaceae-Type Cyclopeptide from Rubia podantha, Indicating an Important Role of the N9-Methyl Group in the Conformation and Bioactivity

One new cyclic hexapeptide named rubipodanin A (1), which is the first identified natural N-desmonomethyl Rubiaceae-type cyclopeptide, together with six known Rubiaceae-type cyclopeptides (2–7) were obtained using the TLC cyclopeptide protosite detection method with ninhydrin from the roots and rhizomes of Rubia podantha. The cyclopeptide structures were elucidated by extensive...

A Study of Network Violator Interception Based on a Reliable Game Model

This study focuses on planning interceptor locations in a general transportation network to maximize the expected benefits from catching violators mixing in public traveler flow. Two reliability-related characteristics are also integrated into the planning model to make it more practical. One is that each interceptor (e.g., a sensor or a checkpoint) has a failure probability. The...

A Study of Network Violator Interception Based on a Reliable Game Model

This study focuses on planning interceptor locations in a general transportation network to maximize the expected benefits from catching violators mixing in public traveler flow. Two reliability-related characteristics are also integrated into the planning model to make it more practical. One is that each interceptor (e.g., a sensor or a checkpoint) has a failure probability. The...

MiR-205 inhibits cell apoptosis by targeting phosphatase and tensin homolog deleted on chromosome ten in endometrial cancer ishikawa cells

Background MicroRNAs (miRNAs) are frequently dysregulated in human cancers and can act as either potent oncogenes or tumor suppressor genes. In the present study, we intend to prove that the gene PTEN (phosphatase and tensin homolog deleted on chromosome ten) is a target gene of miR-205 and to investigate the suppressive effects on PTEN transcriptional activity by enhancing miR...

Numerical Analysis of an -Galerkin Mixed Finite Element Method for Time Fractional Telegraph Equation

We discuss and analyze an -Galerkin mixed finite element (-GMFE) method to look for the numerical solution of time fractional telegraph equation. We introduce an auxiliary variable to reduce the original equation into lower-order coupled equations and then formulate an -GMFE scheme with two important variables. We discretize the Caputo time fractional derivatives using the finite...