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Biocompatible 5-Aminolevulinic Acid/Au Nanoparticle-Loaded Ethosomal Vesicles for In Vitro Transdermal Synergistic Photodynamic/Photothermal Therapy of Hypertrophic Scars

Biocompatible 5-aminolevulinic acid/Au nanoparticle-loaded ethosomal vesicle (A/A-ES) is prepared via ultrasonication for synergistic transdermal photodynamic/photothermal therapy (PDT/PTT) of hypertrophic scar (HS). Utilizing ultrasonication, Au nanoparticles (AuNPs) are synthesized and simultaneously loaded in ethosomal vesicles (ES) without any toxic agents, and 5...

The Epidemiology of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in China

Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN) are life-threatening disease. However, there are only few epidemiologic studies of SJS/TEN from China. To analyze the clinical characteristics, causality, and outcome of treatment for SJS/TEN in China, we reviewed case reports of patients with SJS/TEN from the China National Knowledge Infrastructure (CNKI) and...

Aberrant Expression of miR-362 Promotes Lung Cancer Metastasis through Downregulation of Sema3A

’ Contributions Dan Luo, Zheng Zhang, and Zhi-Nan Chen conceived and designed the experiments. Dan Luo and Zhao Zhang performed the experiments. Dan Luo and Jian Cui analyzed the data. Jia-Yue Li, Lin Yuan, and ... . Wen-Pu Shi and Xi-Wen Dong revised the manuscript. Dan Luo, Zheng Zhang, and Zhao Zhang contributed equally to this work. Funding This study was supported by the Natural Science Foundation of China

Aberrant Expression of miR-362 Promotes Lung Cancer Metastasis through Downregulation of Sema3A

’ Contributions Dan Luo, Zheng Zhang, and Zhi-Nan Chen conceived and designed the experiments. Dan Luo and Zhao Zhang performed the experiments. Dan Luo and Jian Cui analyzed the data. Jia-Yue Li, Lin Yuan, and ... . Wen-Pu Shi and Xi-Wen Dong revised the manuscript. Dan Luo, Zheng Zhang, and Zhao Zhang contributed equally to this work. Funding This study was supported by the Natural Science Foundation of China

Aberrant Expression of miR-362 Promotes Lung Cancer Metastasis through Downregulation of Sema3A

’ Contributions Dan Luo, Zheng Zhang, and Zhi-Nan Chen conceived and designed the experiments. Dan Luo and Zhao Zhang performed the experiments. Dan Luo and Jian Cui analyzed the data. Jia-Yue Li, Lin Yuan, and ... . Wen-Pu Shi and Xi-Wen Dong revised the manuscript. Dan Luo, Zheng Zhang, and Zhao Zhang contributed equally to this work. Funding This study was supported by the Natural Science Foundation of China

Effect of omega-3 long-chain polyunsaturated fatty acid supplementation on heart rate: a meta-analysis of randomized controlled trials

, Suzhou, 215123, ChinaKhemayanto Hidayat, Jing Yang, Zheng Zhang, Guo-Chong Chen & Li-Qiang QinDSM Nutritional Products, Human Nutrition and Health, 4303, Kaiseraugst, SwitzerlandManfred EggersdorferDSM ... Research journals • PubMed • Google Scholar Search for Zheng Zhang in:Nature Research journals • PubMed • Google Scholar Search for Guo-Chong Chen in:Nature Research journals • PubMed • Google Scholar

Quantitative characterization of the auxin-inducible degron: a guide for dynamic protein depletion in single yeast cells

Perturbations are essential for the interrogation of biological systems. The auxin-inducible degron harbors great potential for dynamic protein depletion in yeast. Here, we thoroughly and quantitatively characterize the auxin-inducible degron in single yeast cells. We show that an auxin concentration of 0.25 mM is necessary for fast and uniform protein depletion between single...

Optically-controlled bacterial metabolite for cancer therapy

Zhang 0 0 Key Laboratory of Biomedical Polymers of Ministry of Education, Department of Chemistry, Wuhan University , Wuhan, 430072 , China. These authors Bacteria preferentially accumulating in tumor

Anisotropic Elastoplastic Damage Mechanics Method to Predict Fatigue Life of the Structure

New damage mechanics method is proposed to predict the low-cycle fatigue life of metallic structures under multiaxial loading. The microstructure mechanical model is proposed to simulate anisotropic elastoplastic damage evolution. As the micromodel depends on few material parameters, the present method is very concise and suitable for engineering application. The material...

MYCN contributes to the malignant characteristics of erythroleukemia through EZH2-mediated epigenetic repression of p21

Wu Zheng Zhang Xiao Li MYC proto-oncogene family including c-myc and n-myc (MYCN) are critical for normal cell development and tumorigenesis. Overexpression of c-myc causes acute erythroleukemia in

Genetic dissection of main and epistatic effects of QTL based on augmented triple test cross design

. Formal analysis: Xueli Zhang, Congwei Sun, Xiong Yuan. Investigation: Xueli Zhang, Congwei Sun, Zheng Zhang, Zhijun Dai, Yuan Chen, Xiong Yuan. Methodology: Congwei Sun, Zheng Zhang, Zhijun Dai, Yuan

Paneth cells: the hub for sensing and regulating intestinal flora

The complex interplay between symbiotic bacteria and host immunity plays a key role in shaping intestinal homeostasis and maintaining host health. Paneth cells, as one of the major producers of antimicrobial peptides in the intestine under steady-state conditions, play a vital role in regulating intestinal flora. Many studies on inflammatory bowel disease (IBD)-associated genes...

Reconfigurable metasurfaces that enable light polarization control by light

-Zheng Zhang & Jing-Jun XuThe 2011 Project Collaborative Innovation Center for Biological Therapy, Nankai University, Tianjin 300071, ChinaMeng-Xin Ren AuthorsSearch for Meng-Xin Ren in:Nature Research ... Research journals • PubMed • Google ScholarSearch for Xin-Zheng Zhang in:Nature Research journals • PubMed • Google ScholarSearch for Jing-Jun Xu in:Nature Research journals • PubMed • Google Scholar

Faceted interfaces: a key feature to quantitative understanding of transformation morphology

Laboratory, Aerospace Research Institute of Materials and Processing Technology, Beijing, ChinaFu-Zhi Dai AuthorsSearch for Wen-Zheng Zhang in:Nature Research journals • PubMed • Google ScholarSearch for Xin ... . Corresponding author Correspondence to Wen-Zheng Zhang. Rights and permissions This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material

Simulating Study on Drive System Performance for Hybrid Electric Bus Based on ADVISOR

Hybrid electric bus has a number of advantages when compared with ordinary passenger cars, but in the dynamic matching and the vehicle performance are difficult to detect, thus limits its development process. In this paper, combined with the actual models, the hybrid electric bus module parameters were modified in the software of ADVISOR (Advanced Vehicle Simulator), main...

A novel injectable calcium phosphate-based nanocomposite for the augmentation of cannulated pedicle-screw fixation

A novel injectable calcium phosphate-based nanocomposite for the augmentation of cannulated pedicle-screw fixation Haolin Sun,1,* Chun Liu,2,* Huiling Liu,2,* Yanjie Bai,3 Zheng Zhang,1 Xuwen Li,1

Quantitative proteomics in A30P*A53T α-synuclein transgenic mice reveals upregulation of Sel1l

He, Zheng Zhang, Zexi Lv, Hongwei Cai, Bo Tian. Validation: Fengjuan Jiao, Zheng Zhang, Zexi Lv. Visualization: Qingzhi Wang. Writing ± original draft: Jianguo Yan. Writing ± review & editing: Bo

ACRIN 6684: Multicenter, phase II assessment of tumor hypoxia in newly diagnosed glioblastoma using magnetic resonance spectroscopy

, PhD (University of Pennsylvania, Email: David.Mankoff@uphs. upenn.edu) and Study Statistician Zheng Zhang, PhD (Brown University, Email: zzhang@stat. brown.edu). This study was coordinated by the ECOG ... . Andronesi, Akiva Mintz, Lale Kostakoglu, Benjamin Ellingson, Kathleen Schmainda, Gregory Sorensen, Daniel Barboriak, David Mankoff, Elizabeth R. Gerstner. Formal analysis: Zheng Zhang, James Fink, Mark Muzi