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PRAK Interacts with DJ-1 and Prevents Oxidative Stress-Induced Cell Death

; Accepted 27 August 2014; Published 14 October 2014 Academic Editor: Ozcan Erel Copyright © 2014 Jing Tang et al. This is an open access article distributed under the Creative Commons Attribution License

PRAK Interacts with DJ-1 and Prevents Oxidative Stress-Induced Cell Death

; Accepted 27 August 2014; Published 14 October 2014 Academic Editor: Ozcan Erel Copyright © 2014 Jing Tang et al. This is an open access article distributed under the Creative Commons Attribution License

?-Well-Posedness for Mixed Quasi Variational-Like Inequality Problems

January 2011; Revised 18 March 2011; Accepted 14 April 2011 Academic Editor: V. Zeidan Copyright © 2011 Jian-Wen Peng and Jing Tang. This is an open access article distributed under the Creative ... Inequality Problems Jian-Wen Peng and Jing Tang School of Mathematics, Chongqing Normal University, Chongqing 400047, China Received 15 January 2011; Revised 18 March 2011; Accepted 14 April 2011 Academic

Effect of the Herbal Drug Guilu Erxian Jiao on Muscle Strength, Articular Pain, and Disability in Elderly Men with Knee Osteoarthritis

the publication of this paper. Authors’ Contribution Chen-Chen Tsai, Yin-Yi Chou, Yi-Ming Chen, Yih-Jing Tang, and Hui-Ching Ho contributed equally to this work. Acknowledgment The authors thank the ... Tang,6,7 Hui-Ching Ho,8 and Der-Yuan Chen4,5,9 1Department of Traditional Chinese Medicine, Taichung Veterans General Hospital, 1650 Taiwan Boulevard, Section 4, Taichung, 40705, Taiwan 2College of

Target Inhibition Networks: Predicting Selective Combinations of Druggable Targets to Block Cancer Survival Pathways

A recent trend in drug development is to identify drug combinations or multi-target agents that effectively modify multiple nodes of disease-associated networks. Such polypharmacological effects may reduce the risk of emerging drug resistance by means of attacking the disease networks through synergistic and synthetic lethal interactions. However, due to the exponentially...

Proteomic profiling of the phosphoproteins in the rat thalamus, hippocampus and frontal lobe after propofol anesthesia

Background Propofol is a safe and effective intravenous anesthetic that is widely used for the induction and maintenance of anesthesia during surgery. However, the mechanism by which propofol exerts its anesthetic effect remains unknown. The rapid onset of phosphorylation modifications coincides with that of propofol anesthesia. Methods Propofol-anesthetized rat models were built...

Recurrently deregulated lncRNAs in hepatocellular carcinoma

ScholarSearch for Yang Liu in:Nature Research journals • PubMed • Google ScholarSearch for Jing Tang in:Nature Research journals • PubMed • Google ScholarSearch for Guijuan Luo in:Nature Research journals

Mesenchymal stem cells-regulated Treg cells suppress colitis-associated colorectal cancer

Introduction Previous studies have produced controversial results regarding whether mesenchymal stem cells (MSCs) promote or inhibit tumor development. Given the dual role of MSCs in inflammation and cancer, in this study the colitis-associated colorectal cancer (CAC) model was used to examine whether umbilical cord tissue-derived MSCs could prevent neoplasm by inhibiting chronic...

A Small Peptide with Therapeutic Potential for Inflammatory Acne Vulgaris

A designed peptide named LZ1 with 15 amino acid residues containing strong antimicrobial activity against bacteria pathogens of acne vulgaris including Propionibacterium acnes, Staphylococcus epidermidis and S. aureus. Especially, it exerted strong anti-P. acnes ability. The minimal inhibitory concentration against three strains of P. acnes was only 0.6 µg/ml, which is 4 times...

Plasma levels of microRNA-24, microRNA-320a, and microRNA-423-5p are potential biomarkers for colorectal carcinoma

Background MicroRNAs are stable and easy to detect in plasma. The plasma levels of microRNAs are often changed in disease conditions, including cancer. This makes circulating microRNAs a novel class of biomarkers for cancer diagnosis. Analyses of online microRNA data base revealed that expression level of three microRNAs, microRNA-24 (miR-24), microRNA-320a (miR-320a), and...

A Small Peptide with Potential Ability to Promote Wound Healing

, Lixian Mu , Jing Tang , Zilei Duan , Ren Lai et al. ( 2013 ) A Small Peptide with Therapeutic Potential for Inflammatory Acne Vulgaris . PloS One 8 : e72923 . 9. Geoffrey CG , Sabine W , Yann B , Michael

A passerine spreads its tail to facilitate a rapid recovery of its body posture during hovering

We demonstrate experimentally that a passerine exploits tail spreading to intercept the downward flow induced by its wings to facilitate the recovery of its posture. The periodic spreading of its tail by the White-eye bird exhibits a phase correlation with both wingstroke motion and body oscillation during hovering flight. During a downstroke, a White-eye's body undergoes a...

Propofol Inhibits Lipopolysaccharide-Induced Tumor Necrosis Factor-Alpha Expression and Myocardial Depression through Decreasing the Generation of Superoxide Anion in Cardiomyocytes

Shenzhen Hospital, Shenzhen, Guangdong 518053, China Received 18 April 2014; Accepted 16 July 2014; Published 11 August 2014 Academic Editor: Neelam Khaper Copyright © 2014 Jing Tang et al. This is an ... this study. Authors’ Contribution Jing Tang and Ji-Jie Hu contributed equally to this work. Acknowledgments This work was supported by the National Natural Science Foundation of China (81301664 and

Propofol Inhibits Lipopolysaccharide-Induced Tumor Necrosis Factor-Alpha Expression and Myocardial Depression through Decreasing the Generation of Superoxide Anion in Cardiomyocytes

Shenzhen Hospital, Shenzhen, Guangdong 518053, China Received 18 April 2014; Accepted 16 July 2014; Published 11 August 2014 Academic Editor: Neelam Khaper Copyright © 2014 Jing Tang et al. This is an ... this study. Authors’ Contribution Jing Tang and Ji-Jie Hu contributed equally to this work. Acknowledgments This work was supported by the National Natural Science Foundation of China (81301664 and

Is Zolpidem Associated with Increased Risk of Fractures in the Elderly with Sleep Disorders? A Nationwide Case Cross-Over Study in Taiwan

Background We conducted a study using a case-crossover design to clarify the risk of acute effects of zolpidem and benzodiazepine on all-sites of fractures in the elderly. Design of study Case-crossover design. Methods and Materials Elderly enrollees (n = 6010) in Taiwan’s National Health Insurance Research Database with zolpidem or benzodiazepine use were analyzed for the risk...

Longitudinal wave function control in single quantum dots with an applied magnetic field

, Institute of Physics, Chinese Academy of Sciences, Beijing, 100190, ChinaShuo Cao, Jing Tang, Yunan Gao, Yue Sun, Kangsheng Qiu, Yanhui Zhao, Min He, Jin-An Shi, Lin Gu, Kuijuan Jin & Xiulai XuInstitute of ... • PubMed • Google ScholarSearch for Jing Tang in:Nature Research journals • PubMed • Google ScholarSearch for Yunan Gao in:Nature Research journals • PubMed • Google ScholarSearch for Yue Sun in:Nature

Late-life depression and quality of life in a geriatric evaluation and management unit: an exploratory study

Background Late-life depression is common among elderly patients. Ignorance of the health problem, either because of under-diagnosis or under-treatment, causes additional medical cost and comorbidity. For a better health and quality of life (QoL), evaluation, prevention and treatment of late-life depression in elderly patients is essential. Methods This study examined (1) the...

Overexpression of GOLPH3 is associated with poor prognosis and clinical progression in pancreatic ductal adenocarcinoma

Background Golgi phosphoprotein 3 (GOLPH3) has been identified as an oncoprotein in various human cancers; however, its role in pancreatic ductal adenocarcinoma (PDAC) is unknown. We examined GOLPH3 expression levels and relationship with survival in patients with PDAC to establish the significance of GOLPH3 in the development and progression of PDAC. Methods Real-time qPCR and...