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The Relationship between Post-Traumatic Symptoms, Parenting Style, and Resilience among Adolescents in Liaoning, China: A Cross-Sectional Study

Background In China, a growing number of adolescents have experienced traumatic events that have resulted in PTSD (post-traumatic stress disorder). Post-traumatic symptoms are common psychological problems in adolescents who have experienced traumatic events. However, existing studies tend to focus on the factors influencing PTSD, such as the response styles and social support...

Effects of a Randomized Intervention to Improve Workplace Social Capital in Community Health Centers in China

Objective To examine whether workplace social capital improved after implementing a workplace social capital intervention in community health centers in China. Methods This study was conducted in 20 community health centers of similar size in Jinan of China during 2012–2013. Using the stratified site randomization, 10 centers were randomized into the intervention group; one...

Benzothiazinethione is a potent preclinical candidate for the treatment of drug-resistant tuberculosis

New chemotherapeutic compounds are needed to combat multidrug-resistant Mycobacterium tuberculosis (Mtb), which remains a serious public-health challenge. Decaprenylphosphoryl-β-D-ribose 2′-epimerase (DprE1 enzyme) has been characterized as an attractive therapeutic target to address this urgent demand. Herein, we have identified a new class of DprE1 inhibitors...

Amotl2a interacts with the Hippo effector Yap1 and the Wnt/β-catenin effector Lef1 to control tissue size in zebrafish

Sobhika Agarwala Sandra Duquesne Kun Liu Anton Boehm Lin Grimm Sandra Link Sabine König Stefan Eimer Olaf Ronneberger Virginie Lecaudey This PDF is the version of the article that was accepted for

iBrick: A New Standard for Iterative Assembly of Biological Parts with Homing Endonucleases

DNA in vitro (application no. in State Intellectual Property Office of the P.R.C: 01410235720.6) has been filed by CAS Key Laboratory of Synthetic Biology with Jin Wang, Guo-Ping Zhao, Jia-Kun Liu and

ERRATUM: Synthesis of Large and Few Atomic Layers of Hexagonal Boron Nitride on Melted Copper

. Molino Hua Kun Liu There is also a typographical error in the Results section. ''The SAED patterns show several sets of hexagonal patterns, indicating the polycrystalline nature of the sheets within the

Selection for chloroquine-sensitive Plasmodium falciparum by wild Anopheles arabiensis in Southern Zambia

Background The emergence of parasite drug resistance, especially Plasmodium falciparum, persists as a major obstacle for malaria control and elimination. To develop effective public health containment strategies, a clear understanding of factors that govern the emergence and spread of resistant parasites in the field is important. The current study documents selection for...

Rapid increase of scrub typhus incidence in Guangzhou, southern China, 2006―2014

Background In the last decade, scrub typhus (ST) has been emerging or re-emerging in some areas of Asia, including Guangzhou, one of the most affected endemic areas of ST in China. Methods Based on the data on all cases reported in Guangzhou from 2006 to 2014, we characterized the epidemiological features, and identified environmental determinants for the spatial distribution of...

The siRNA cocktail targeting VEGF and HER2 inhibition on the proliferation and induced apoptosis of gastric cancer cell

The aim of this study was to investigate the inhibitory effect of a siRNA cocktail targeting Vascular endothelial growth factor (VEGF) and Human epidermal growth factor receptor 2 (HER2) on cell proliferation, induced apoptosis and the expression of VEGF and HER2 in human gastric carcinoma cell. The silencing rate of pre-designed siRNAs that targeted VEGF and HER2 was detected by...

Influence of Copper Nanoparticles on the Physical-Chemical Properties of Activated Sludge

The physical-chemical properties of activated sludge, such as flocculating ability, hydrophobicity, surface charge, settleability, dewaterability and bacteria extracellular polymer substances (EPS), play vital roles in the normal operation of wastewater treatment plants (WWTPs). The nanoparticles released from commercial products will enter WWTPs and can induce potential adverse...

Synthesis of Large and Few Atomic Layers of Hexagonal Boron Nitride on Melted Copper

in:Nature Research journals • PubMed • Google ScholarSearch for Hua Kun Liu in:Nature Research journals • PubMed • Google Scholar Contributions M.H.K. and Z.H. designed the experiment and co-wrote the paper

The role of chemotherapy and operation on lymphocytes accumulation in peripheral blood obtained from patients with oral squamous cell carcinoma

Jiafeng Zhao Lichun Wu Chunhua Li Kun Liu Guiquan Zhu Jin Chen Chuan Xu Yongcong Cai Jifeng Liu Zhaohui Wang The “Cancer Immunoediting” concept has provided critical insights suggesting dual functions of

Irregular transcriptome reprogramming probably causes thec developmental failure of embryos produced by interspecies somatic cell nuclear transfer between the Przewalski’s gazelle and the bovine

Background Interspecies somatic cell nuclear transfer (iSCNT) has been regarded as a potential alternative for rescuing highly endangered species and can be used as a model for studying nuclear–cytoplasmic interactions. However, iSCNT embryos often fail to produce viable offspring. The alterations in normal molecular mechanisms contributing to extremely poor development are for...

Seasonal Dynamics of the Plant Community and Soil Seed Bank along a Successional Gradient in a Subalpine Meadow on the Tibetan Plateau

Background Knowledge about how change the importance of soil seed bank and relationship between seed mass and abundance during vegetation succession is crucial for understanding vegetation dynamics. Many studies have been conducted, but their ecological mechanisms of community assembly are not fully understood. Methodology We examined the seasonal dynamics of the vegetation and...

Investigation of Variants in UCP2 in Chinese Type 2 Diabetes and Diabetic Retinopathy

Purpose The aim of this study was to investigate variants in UCP2 genes in type 2 diabetes mellitus (DM) and diabetic retinopathy (DR) in Chinese population. Materials and Methods We conducted a single nucleotide polymorphism-based and haplotype-based case-control study between the variants of UCP2 and DM and between the variants of UCP2 and DR in 479 Chinese patients with type 2...

Organ-Specific Splice Variants of Aquaporin Water Channel AgAQP1 in the Malaria Vector Anopheles gambiae

BackgroundAquaporin (AQP) water channels are important for water homeostasis in all organisms. Malaria transmission is dependent on Anopheles mosquitoes. Water balance is a major factor influencing mosquito survival, which may indirectly affect pathogen transmission. Methodology/Principal FindingsWe obtained full-length mRNA sequences for Anopheles gambiae aquaporin 1 (AgAQP1...

Late Eocene to early Oligocene quantitative paleotemperature record: Evidence from continental halite fluid inclusions

Climate changes within Cenozoic extreme climate events such as the Paleocene–Eocene Thermal Maximum and the First Oligocene Glacial provide good opportunities to estimate the global climate trends in our present and future life. However, quantitative paleotemperatures data for Cenozoic climatic reconstruction are still lacking, hindering a better understanding of the past and...

The Spatiotemporal Expansion of Human Rabies and Its Probable Explanation in Mainland China, 2004-2013

Background Human rabies is a significant public health concern in mainland China. However, the neglect of rabies expansion and scarce analyses of the dynamics have made the spatiotemporal spread pattern of human rabies and its determinants being poorly understood. Methods We collected geographic locations and timeline of reported human rabies cases, rabies sequences and...

A first generation BAC-based physical map of the half-smooth tongue sole (Cynoglossus semilaevis) genome

Background Half-smooth tongue sole (Cynoglossus semilaevis Günther) has been exploited as a commercially important cultured marine flatfish, and female grows 2–3 times faster than male. Genetic studies, especially on the chromosomal sex-determining system of this species, have been carried out in the last decade. Although the genome of half-smooth tongue sole was relatively small...

Foot Drop Caused by Lumbar Degenerative Disease: Clinical Features, Prognostic Factors of Surgical Outcome and Clinical Stage

ObjectiveThe purpose of this study was to analyze the clinical features and prognostic factors of surgical outcome of foot drop caused by lumbar degenerative disease and put forward the clinical stage. MethodsWe retrospectively reviewed 135 patients with foot drop due to lumbar degenerative disease. The clinical features and mechanism were analyzed. Age, sex, duration of palsy...