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Genome-wide analysis reveals adaptation to high altitudes in Tibetan sheep

Wei, Huihua Wang, Fuping Zhao, Li Zhang, Jiaxue Cao, Mingming Wu, Guangkai Wang, Ruizao Liu, Zhen Liu, Shuzhen Zhang & Lixin DuNational Animal Husbandry Service, National Center of Preservation ... for Youji Ma in:Nature Research journals • PubMed • Google ScholarSearch for Jian Lu in:Nature Research journals • PubMed • Google ScholarSearch for Li Zhang in:Nature Research journals • PubMed

Synergistic anti-tumor therapy by a comb-like multifunctional antibody nanoarray with exceptionally potent activity

200433, ChinaHuafei Li, Yun Sun, Di Chen, He Zhao, Mengxin Zhao, Xiandi Zhu, Changhong Ke, Ge Zhang, Cheng Jiang, Li Zhang, Fulei Zhang, Huafeng Wei & Wei LiState Key Laboratory of Antibody Medicine and ... • PubMed • Google ScholarSearch for Li Zhang in:Nature Research journals • PubMed • Google ScholarSearch for Fulei Zhang in:Nature Research journals • PubMed • Google ScholarSearch for Huafeng Wei in:Nature

Ginkgolide B protects human umbilical vein endothelial cells against xenobiotic injuries via PXR activation

the experiments, analyzed the data and drafted the manuscript; Zengchun MA, Qian-de LIANG, Xiang-lin TANG, Hong-ling TAN and Cheng-rong XIAO assisted with in the experiments; Bo-li ZHANG and Yue GAO

Hypertension associated with venous thromboembolism in patients with newly diagnosed lung cancer

The aim of this study was to evaluate associations between cardiovascular disease (CVD) risk factors and the occurrence of venous thromboembolism (VTE) in patients with lung cancer that might help estimate an individual’s risk for VTE. A total of 632 unselected patients with newly diagnosed lung cancer were investigated for VTE within the three months prior to recruitment, and...

Distribution of Axial Length before Cataract Surgery in Chinese Pediatric Patients

, Jingjing Chen, Lixia Luo, Zhuoling Lin, Xiaohang Wu, Erping Long, Li Zhang, Hui Chen, Wan Chen, Bo Zhang, Jinchao Liu, Xiaoyan Li, Weirong Chen & Yizhi Liu AuthorsSearch for Haotian Lin in:Nature Research ... ScholarSearch for Erping Long in:Nature Research journals • PubMed • Google ScholarSearch for Li Zhang in:Nature Research journals • PubMed • Google ScholarSearch for Hui Chen in:Nature Research journals • PubMed

Identification of a hybrid myocardial zone in the mammalian heart after birth

Scholar Search for Ying Yu in:Nature Research journals • PubMed • Google Scholar Search for Li Zhang in:Nature Research journals • PubMed • Google Scholar Search for Yan Yan in:Nature Research journals

Vascular Normalization Induced by Sinomenine Hydrochloride Results in Suppressed Mammary Tumor Growth and Metastasis

, Xiaojiang Tang, Ke Wang, Yang Liu, Li Zhang, Xiao Li & Jianjun HeTranslational Medical center, The First Affiliated Hospital of Xi'an Jiaotong University, 277 West Yanta Road, Xi'an 710061, P.R. ChinaPeijun ... in:Nature Research journals • PubMed • Google ScholarSearch for Yang Liu in:Nature Research journals • PubMed • Google ScholarSearch for Li Zhang in:Nature Research journals • PubMed • Google ScholarSearch

Targeted next-generation sequencing reveals multiple deleterious variants in OPLL-associated genes

Ossification of the posterior longitudinal ligament of the spine (OPLL), which is characterized by ectopic bone formation in the spinal ligaments, can cause spinal-cord compression. To date, at least 11 susceptibility genes have been genetically linked to OPLL. In order to identify potential deleterious alleles in these OPLL-associated genes, we designed a capture array...

Lapatinib-incorporated lipoprotein-like nanoparticles: preparation and a proposed breast cancer-targeting mechanism

HE designed the study; Li ZHANG performed the experiments and wrote the paper with the assistance of Shuang ZHANG, Shao-bo RUAN and Qian-yu ZHANG. References 1. Moreira C, Kaklamani V. Lapatinib ... Delivery, Ministry of Education, Shanghai 201203, ChinaShuang Zhang AuthorsSearch for Li Zhang in:Nature Research journals • PubMed • Google ScholarSearch for Shuang Zhang in:Nature Research journals

Prevalence of Corneal Astigmatism and Anterior Segmental Biometry Characteristics Before Surgery in Chinese Congenital Cataract Patients

Lin, Xiaoyan Li, Li Zhang, Hui Chen, Jinchao Liu, Weirong Chen, Haotian Lin & Yizhi Liu AuthorsSearch for Duoru Lin in:Nature Research journals • PubMed • Google ScholarSearch for Jingjing Chen ... • PubMed • Google ScholarSearch for Xiaoyan Li in:Nature Research journals • PubMed • Google ScholarSearch for Li Zhang in:Nature Research journals • PubMed • Google ScholarSearch for Hui Chen in:Nature

Understanding complete oxidation of methane on spinel oxides at a molecular level

It is crucial to develop a catalyst made of earth-abundant elements highly active for a complete oxidation of methane at a relatively low temperature. NiCo2O4 consisting of earth-abundant elements which can completely oxidize methane in the temperature range of 350–550 °C. Being a cost-effective catalyst, NiCo2O4 exhibits activity higher than precious-metal-based catalysts. Here...

A High-Throughput, Multi-Cell Phenotype Assay for the Identification of Novel Inhibitors of Chemotaxis/Migration

Chemotaxis and cell migration are fundamental, universal eukaryotic processes essential for biological functions such as embryogenesis, immunity, cell renewal, and wound healing, as well as for pathogenesis of many diseases including cancer metastasis and chronic inflammation. To identify novel chemotaxis inhibitors as probes for mechanistic studies and leads for development of...

Establishment of a rat model of lumbar facet joint osteoarthritis using intraarticular injection of urinary plasminogen activator

Lumbar facet joint (LFJ) osteoarthritis (OA) is an important etiology of low back pain. Several animal models of LFJ OA have been established using intraarticular injection of various chemicals. This study aimed to establish a rat model of LFJ OA using urinary plasminogen activator (uPA). Sprague-Dawley rats were treated with intraarticular injection in the L5-L6 facet joints...

Indian Hedgehog signaling pathway members are associated with magnetic resonance imaging manifestations and pathological scores in lumbar facet joint osteoarthritis

Jia-Liang Zhu Yan Liu Chun-Li Zhang Jia-Guang Tang Scientific RepoRts OPEN Indian Hedgehog (HH) has been shown to be involved in osteoarthritis (OA) in articular joints, where there is evidence that

Microarray Profiling and Co-Expression Network Analysis of LncRNAs and mRNAs in Neonatal Rats Following Hypoxic-ischemic Brain Damage

Science Foundation of China (No. 81330016 and 31171020 to Dezhi Mu; No. 81172174 and 81270724 to Yi Qu; No. 81300526 to Fengyan Zhao; No. 81200462 to Li Zhang), the Major State Basic Research Development

Progress and challenges in the use of latent HIV-1 reactivating agents

ScholarSearch for Tao Wu in:Nature Research journals • PubMed • Google ScholarSearch for Qiu-li Zhang in:Nature Research journals • PubMed • Google ScholarSearch for Fu-jun Liang in:Nature Research journals

The Knockout of Secretin in Cerebellar Purkinje Cells Impairs Mouse Motor Coordination and Motor Learning

, University of Hong Kong, Hong Kong SAR, ChinaSookja Kim Chung AuthorsSearch for Li Zhang in:Nature Research journals • PubMed • Google ScholarSearch for Sookja Kim Chung in:Nature Research journals • PubMed

Automatic Three-dimensional Detection of Photoreceptor Ellipsoid Zone Disruption Caused by Trauma in the OCT

Enting Gao Li Zhang YilongYin Xinjian Chen OPEN Detection and assessment of the integrity of the photoreceptor ellipsoid zone (EZ) are important because it is critical for visual acuity in retina trauma

Chitosan/siCkip-1 biofunctionalized titanium implant for improved osseointegration in the osteoporotic condition

Medical University, No. 145 West Changle Road, Xi’an 710032, ChinaHaiyan Xu, Ran An & Bin Liu AuthorsSearch for Li Zhang in:Nature Research journals • PubMed • Google ScholarSearch for Kaimin Wu in:Nature