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Engineering an inducible gene expression system for Bacillus subtilis from a strong constitutive promoter and a theophylline-activated synthetic riboswitch

Background Synthetic riboswitches have been increasingly used to control and tune gene expression in diverse organisms. Although a set of theophylline-responsive riboswitches have been developed for bacteria, fully functional expression elements mediated by synthetic riboswitches in Bacillus subtilis are rarely used because of the host-dependent compatibility between the...

Location and moment tensor inversion of small earthquakes using 3D Green’s functions in models with rugged topography: application to the Longmenshan fault zone

With dense seismic arrays and advanced imaging methods, regional three-dimensional (3D) Earth models have become more accurate. It is now increasingly feasible and advantageous to use a 3D Earth model to better locate earthquakes and invert their source mechanisms by fitting synthetics to observed waveforms. In this study, we develop an approach to determine both the earthquake...

Identification of 11(13)-dehydroivaxillin as a potent therapeutic agent against non-Hodgkin's lymphoma

Yin Tong Li Zhou Hu Lei Hanzhang Xu Weidong Zhang Wei Liu Yingli Wu Despite great advancements in the treatment of non-Hodgkin lymphoma (NHL), sensitivity of different subtypes to therapy varies

Rosuvastatin Attenuates CD40L-Induced Downregulation of Extracellular Matrix Production in Human Aortic Smooth Muscle Cells via TRAF6-JNK-NF-κB Pathway

CD40L and statins exhibit pro-inflammatory and anti-inflammatory effects, respectively. They are both pleiotropic and can regulate extracellular matrix (ECM) degeneration in an atherosclerotic plaque. Statins can decrease both the CD40 expression and the resulting inflammation. However, the effects of CD40L and stains on atherosclerotic plaque ECM production and the underlying...

A statistical analysis plan for the efficiency and safety of Chinese herbal medicine used concurrently with topical therapy for psoriasis vulgaris

Background Psoriasis vulgaris (PV) has been causing increasing concern due to its highly prevalent, harmful and therapy-resistant characteristics. The YXBCM01 (Chinese herbal medicine) for PV trial evaluates the effects of YXBCM01 on relapse rate in patients suffering from PV. As an update to the published design and method for the trial, this paper presents the statistical plan...

Associations of Different Adipose Tissue Depots with Insulin Resistance: A Systematic Review and Meta-analysis of Observational Studies

Fat distribution is strongly associated with insulin resistance, a risk factor for type 2 diabetes and cardiovascular diseases. However, associations of different adipose tissue depots or/and obesity indices with insulin resistance have not been systematically evaluated. In this study we examined associations of different adipose tissue depots/obesity indices with insulin...

Tuning of Exchange Coupling and Switchable Magnetization Dynamics by Displacing the Bridging Ligands Observed in Two Dimeric Manganese(III) Compounds

for Li-Zhou Wu in:Nature Research journals • PubMed • Google ScholarSearch for Fei-Fei Li in:Nature Research journals • PubMed • Google ScholarSearch for Wei-Ming Song in:Nature Research journals

Long intergenic non-coding RNA 271 is predictive of a poorer prognosis of papillary thyroid cancer

performed the experiments and wrote the paper; Li Zhou and Shuwen Yang collected the samples and clinicopathogical data of patients; Ben Ma and Chuanpeng Dong were responsible for all bioinformatics and

An Image Defogging Approach Based on a Constrained Energy Functional under Bayesian and Variation Theories

Engineering College, Air Force Engineering University, Xi’an 710038, China Received 31 March 2015; Accepted 12 July 2015 Academic Editor: Alessandro Gasparetto Copyright © 2015 Li Zhou et al. This is an

Genome-wide association analysis identifies resistance loci for bacterial blight in a diverse collection of indica rice germplasm

Natural Science Foundation of China 31661143009 to Yong-Li Zhou; National High-tech Program of China 2014AA10A603 to Yong-Li Zhou; the CAAS Innovative Team Award; and the Bill and Melinda Gates Foundation

The MiR-135b–BMAL1–YY1 loop disturbs pancreatic clockwork to promote tumourigenesis and chemoresistance

Jiang, Yangyang Hu, Kai Li, Sisi Li, Li Zhou, Li Huang, Zhanjun Lu, Yun Feng, Lijuan Yang & Rong WanShanghai Key Laboratory of Pancreatic Disease, Institute of Pancreatic Disease, Shanghai Jiao Tong ... University School of Medicine, Shanghai, ChinaWeiliang Jiang, Yangyang Hu, Kai Li, Sisi Li, Li Zhou, Li Huang, Zhanjun Lu, Yun Feng, Lijuan Yang & Rong WanDepartment of General Surgery, Shanghai General

The effects of forest type on soil microbial activity in Changbai Mountain, Northeast China

Key message Forty years after clear-cutting mixed old-growth forest (broadleaf/Korean pine) in the Changbai Mountain area (Northeast China), a mixed forest with natural broadleaf regeneration and larch plantation displayed larger microbial biomass and activity in the soil than either a naturally regenerated birch forest or a monospecific spruce plantation. Context Clear-cutting...

Origin of unusual HREE-Mo-rich carbonatites in the Qinling orogen, China

Carbonatites, usually occurring within intra-continental rift-related settings, have strong light rare earth element (LREE) enrichment; they rarely contain economic heavy REE (HREE). Here, we report the identification of Late Triassic HREE-Mo-rich carbonatites in the northernmost Qinling orogen. The rocks contain abundant primary HREE minerals and molybdenite. Calcite-hosted...

Effects of reduced nitrogen inputs on crop yield and nitrogen use efficiency in a long-term maize-soybean relay strip intercropping system

. Funding acquisition: Taiwen Yong. Investigation: Ping Chen, Qing Du, Xiaoming Liu, Li Zhou, Lu Lei. Methodology: Ping Chen, Qing Du, Xiaoming Liu, Li Zhou, Lu Lei, Chun Song, Xiaochun Wang, Weiguo Liu ... , Xiaoming Liu, Taiwen Yong. Writing ± review & editing: Ping Chen, Qing Du, Xiaoming Liu, Li Zhou, Sajad Hussain, Chun Song, Xiaochun Wang, Weiguo Liu, Feng Yang, Kai Shu, Jiang Liu, Junbo Du, Wenyu Yang

Development of an efficient autoinducible expression system by promoter engineering in Bacillus subtilis

Liu 0 Zhemin Zhou 0 0 Chengran Guan, Wenjing Cui, Jintao Cheng, Li Zhou, Zhongmei Liu and School of Biotechnology, Key Laboratory of Industrial Biotechnology (Ministry of Education), Jiangnan University

Enhanced thermal conductivity of epoxy composites filled with silicon carbide nanowires

• Google Scholar Search for Li Zhou in:Nature Research journals • PubMed • Google Scholar Search for Yuanli Liu in:Nature Research journals • PubMed • Google Scholar Search for Wen Dai in:Nature Research

Porcine diazepam-binding inhibitor and bovine diazepam-binding inhibitor affect morphine antinociception via different receptors

, Xiao-Cun Li, Zhen-Quan Guo, Li Zhou, Zhuan Zhou, Song-νve no conflict of interest. This article does not contain any studies with human subjects performed by the any of the authors. All institutional and

Analysis of effects of a new environmental pollutant, bisphenol A, on antioxidant systems in soybean roots at different growth stages

University, Wuxi 214122, ChinaJiazhi Zhang, Xingyi Li, Li Zhou, Lihong Wang & Qing ZhouJiangsu Collaborative Innovation Center of Biomedical Functional Materials, Jiangsu Key Laboratory of Biomedical Materials ... University of Science and Technology, Suzhou 215009, ChinaJiazhi Zhang, Xingyi Li, Li Zhou, Lihong Wang & Qing Zhou AuthorsSearch for Jiazhi Zhang in:Nature Research journals • PubMed • Google ScholarSearch

Quantitative study on the fate of residual soil nitrate in winter wheat based on a 15N-labeling method

A considerable amount of surplus nitrogen (N), which primarily takes the form of nitrate, accumulates in the soil profile after harvesting crops from an intensive production system in the North China Plain. The residual soil nitrate (RSN) is a key factor that is included in the N recommendation algorithm. Quantifying the utilization and losses of RSN is a fundamental necessity...

New Set-Valued Integral in a Banach Space

, Beijing Institute of Technology, Beijing 100081, China Received 26 October 2014; Accepted 27 February 2015 Academic Editor: Wilfredo Urbina Copyright © 2015 Cai-Li Zhou and Fu-Gui Shi. This is an open