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Human Umbilical Cord MSC-Derived Exosomes Suppress the Development of CCl4-Induced Liver Injury through Antioxidant Effect

Mesenchymal stem cells (MSCs) have been increasingly applied into clinical therapy. Exosomes are small (30–100 nm in diameter) membrane vesicles released by different cell types and possess the similar functions with their derived cells. Human umbilical cord MSC-derived exosomes (hucMSC-Ex) play important roles in liver repair. However, the effects and mechanisms of hucMSC-Ex on...

Hierarchical Porous Interlocked Polymeric Microcapsules: Sulfonic Acid Functionalization as Acid Catalysts

Owing to their unique structural and surface properties, mesoporous microspheres are widely applied in the catalytic field. Generally, increasing the surface area of the specific active phase of the catalyst is a good method, which can achieve a higher catalytic activity through the fabrication of the corresponding catalytic microspheres with the smaller size and hollow structure...

Pre-culture Sudan Black B treatment suppresses autofluorescence signals emitted from polymer tissue scaffolds

In tissue engineering, autofluorescence of polymer scaffolds often lowers the image contrast, making it difficult to examine cells and subcellular structures. Treating the scaffold materials with Sudan Black B (SBB) after cell fixation can effectively suppress autofluorescence, but this approach is not conducive to live cell imaging. Post-culture SBB treatment also disrupts...

Neuroprotective Effect of Modified Xijiao Dihuang Decoction against Oxygen-Glucose Deprivation and Reoxygenation-Induced Injury in PC12 Cells: Involvement of TLR4-MyD88/NF-κB Signaling Pathway

2017 Academic Editor: Nunziatina De Tommasi Copyright © 2017 Xu Zhang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use ... . Conflicts of Interest The authors declare no conflicts of interest with the content of the paper. Authors’ Contributions Xu Zhang and Xiaojun Fei performed the majority of the experiments and designed the

Developing novel methods to image and visualize 3D genomes

To investigate three-dimensional (3D) genome organization in prokaryotic and eukaryotic cells, three main strategies are employed, namely nuclear proximity ligation-based methods, imaging tools (such as fluorescence in situ hybridization (FISH) and its derivatives), and computational/visualization methods. Proximity ligation-based methods are based on digestion and re-ligation of...

Androgen receptor increases hematogenous metastasis yet decreases lymphatic metastasis of renal cell carcinoma

for Xintao Li in:Nature Research journals • PubMed • Google Scholar Search for Yuanjie Niu in:Nature Research journals • PubMed • Google Scholar Search for Xu Zhang in:Nature Research journals ... . Corresponding authors Correspondence to Xu Zhang or Chawnshang Chang. Electronic supplementary material Supplementary Information Rights and permissions Open Access This article is licensed under a

Intracellular pH Regulates TRAIL-Induced Apoptosis and Necroptosis in Endothelial Cells

, Western University, London, ON, Canada Correspondence should be addressed to Zhu-Xu Zhang; ac.no.cshl@gnahz.uxuhz and Anthony M. Jevnikar; ac.owu@rakinvej Received 15 March 2017; Revised 26 May 2017 ... ; Accepted 5 July 2017; Published 13 August 2017 Academic Editor: Hai Huang Copyright © 2017 Zhu-Xu Zhang et al. This is an open access article distributed under the Creative Commons Attribution License

Intracellular pH Regulates TRAIL-Induced Apoptosis and Necroptosis in Endothelial Cells

, Western University, London, ON, Canada Correspondence should be addressed to Zhu-Xu Zhang; ac.no.cshl@gnahz.uxuhz and Anthony M. Jevnikar; ac.owu@rakinvej Received 15 March 2017; Revised 26 May 2017 ... ; Accepted 5 July 2017; Published 13 August 2017 Academic Editor: Hai Huang Copyright © 2017 Zhu-Xu Zhang et al. This is an open access article distributed under the Creative Commons Attribution License

Gastric precancerous diseases classification using CNN with a concise model

. Author Contributions Conceptualization: Jiquan Liu. Data curation: Weiling Hu, Fei Chen, Liangjing Wang. 8 / 10 Funding acquisition: Jiquan Liu. Investigation: Xu Zhang, Weiling Hu, Fei Chen ... . Methodology: Xu Zhang, Jiquan Liu, Yuanhang Yang. Project administration: Jiquan Liu. Resources: Weiling Hu, Fei Chen. Software: Xu Zhang, Yuanhang Yang. Supervision: Weiling Hu, Jiquan Liu, Liangjing Wang

Voltage Balancing Method on Expert System for 51-Level MMC in High Voltage Direct Current Transmission

2016 Academic Editor: Tarek Ahmed-Ali Copyright © 2016 Yong Chen and Xu Zhang. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use

Guided bone regeneration with asymmetric collagen-chitosan membranes containing aspirin-loaded chitosan nanoparticles

Hongjie Li,1 Chenyuan Gao,2 Xu Zhang,1 Ping Gao1 1School of Dentistry, Hospital of Stomatology, Tianjin Medical University, Tianjin, 2Beijing Laboratory of Biomedical Materials, Beijing University of

Quantitative inheritance of volatile pheromones and darcin and their interaction in olfactory preferences of female mice

Zhang Yao-Hua Zhang OPEN Published: xx xx xxxx In this study, we examined how urine-borne volatile compounds (UVCs) and darcin of male mice are inherited from parents and interact to modulate the

Genetic Diversity and Association Analysis for Solvent Retention Capacity in the Accessions Derived from Soft Wheat Ningmai 9

Solvent retention capacity (SRC) test is an effective method for quality evaluation of soft wheat. Ningmai 9 is a founder in soft wheat breeding. The SRC and genotype of Ningmai 9 and its 117 derivatives were tested. Association mapping was employed to identify the quantitative trait loci (QTL) associated with SRCs. Ningmai 9 had the allele frequency of 75.60% and 67.81% to its...

Fluid-Elastic Instability Tests on Parallel Triangular Tube Bundles with Different Mass Ratio Values under Increasing and Decreasing Flow Velocities

Copyright © 2016 Xu Zhang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium

Fluid-Elastic Instability Tests on Parallel Triangular Tube Bundles with Different Mass Ratio Values under Increasing and Decreasing Flow Velocities

Copyright © 2016 Xu Zhang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium

Fluid-Elastic Instability Tests on Parallel Triangular Tube Bundles with Different Mass Ratio Values under Increasing and Decreasing Flow Velocities

Copyright © 2016 Xu Zhang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium

Semisolid slurry of 7A04 aluminum alloy prepared by electromagnetic stirring and Sc, Zr additions

Slurry preparation is one of the most critical steps for semisolid casting, and its primary goal is to prepare slurry with uniformly distributed fine globules. In this work, electromagnetic stirring (EMS) and the addition of Sc and Zr elements were used to prepare semisolid slurry of 7A04 aluminum alloy in a large diameter slurry maker. The effects of different treatments on the...

Progressive FastICA Peel-Off and Convolution Kernel Compensation Demonstrate High Agreement for High Density Surface EMG Decomposition

Decomposition of electromyograms (EMG) is a key approach to investigating motor unit plasticity. Various signal processing techniques have been developed for high density surface EMG decomposition, among which the convolution kernel compensation (CKC) has achieved high decomposition yield with extensive validation. Very recently, a progressive FastICA peel-off (PFP) framework has...

Progressive FastICA Peel-Off and Convolution Kernel Compensation Demonstrate High Agreement for High Density Surface EMG Decomposition

Decomposition of electromyograms (EMG) is a key approach to investigating motor unit plasticity. Various signal processing techniques have been developed for high density surface EMG decomposition, among which the convolution kernel compensation (CKC) has achieved high decomposition yield with extensive validation. Very recently, a progressive FastICA peel-off (PFP) framework has...